PCC-ring induction in human lymphocytes exposed to gamma and neutron irradiation

Journal of Radiation Research

Volumn 48, Issue 1, 2007, Pages 1-6

  Lamadrid, Ana I ^a   García, Omar ^a   Delbos, Martine ^b   Voisin, Philippe ^b   Roy, Laurence ^b  

^a Laboratorio de Radiobiología   (Cuba)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

Author keywords

Calyculin A; Dose effect curves; High doses radiation; Human lymphocytes; PCC rings

Indexed keywords

CHROMOSOMES; LYMPHOCYTES; NEUTRON IRRADIATION; NEUTRONS;

BIOLOGICAL INDICATORS; CALYCULIN A; DOSE EFFECTS; DOSE-EFFECT CURVE; EXPOSED TO; HIGH DOSE; HIGH DOSE RADIATION; HUMAN LYMPHOCYTES; PREMATURE CHROMOSOME CONDENSATION-RING; PREMATURE CHROMOSOME CONDENSATIONS;

GAMMA RAYS;

EID: 33846874848     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.0625     Document Type: Article

References (15)

1. Kanda, R., Hayata, J., and Lloyd, D. C. (1999a) Easy biodosimetry for high-dose radiation exposures using drug-induced, prematurely condensed chromosomes. Int. J. Radiat. Biol. 75: 441-446.
2. Gotoh, E., and Asakawa, Y. (1996) Detection and evaluation of chromosomal aberrations induced by high dose gamma irradiation using inmunogold-silver painting of premature condensed chromosomes. Int. J. Radiat. Biol. 70: 517-520.
3. Gotoh, E., Tanno, Y., and Takakura, K. (2005) Simple biodosimetry method for use in cases of high dose radiation exposure that scores the chromosome number of giemsa-stained drug-induced prematurely condensed chromosomes (PCC). Int. Radiat. Biol. 81: 33-40.
4. Prouza, Z., Obraz, O., Sopko, B., et al. (1989) Dosimetric parameters of a new Czechoslovak neutron Si diode. Radiat. Prot. Dos. 28: 277-281.
5. Papworth, D. G. (1970) Appendix in: Savage J. R. K. Sites of radiation induced chromosome exchanges. Curr. Top. Radiat. Res. 6: 129-194.
6. Edwards, A. A. (1990) Dosimetric and statistical aspects of cytogenetics. Reunión internacional sobre Dosimetria Biologica. 75-85.
7. Papworth, D.G. (1975) Curve fitting by maximum likelihood. Appendix to paper by J.R.K. Savage: Radiation-induced chromosomal aberrations in plant Tradescantia: Dose response curves. Radiat. Bot. 15: 127-131.
8. Kanda, R., Eguchi-Kosai, K., and Hayata, I. (1999b) Phosphatase inhibitors and premature chromosome condensation in human peripheral lymphocytes at different cell cycle phases. Somatic Cell and Molecular Genetics 25: 1-8.
9. Darroudi, F., Natarajan, A. T., Bentvelzen, P. A., Heidt, P. J., Van Rotterdam, A., Zoetelief, J., Broerse, J. J. (1998) Detection of total and partial body irradiation in a monkey model: a comparative study of chromosomal aberration, micronucleus and premature chromosome condensation assays. Int. J. Radiat. Biol. 74: 207-215.
10. Edwards, A. A., Lloyd, D. C., and Purrot, R. J. (1979) Radiation induced chromosome aberrations and the Poisson distribution. Radiat. Envirom. Biophys. 16: 89-100.
11. IAEA Technical Reports Series No. 405 (2001) Cytogenetic Analysis for Radiation Dose Assessment A Manual. International Atomic Energy Agency, Vienna. P. 47.
12. Kanda, R., Minamihusamatsu, M., and Hayata, I. (2002) Dynamic analysis of chromosome aberrations in three victims of the Tokai-mura criticality accident. Int. J. Radiat. Biol. 9: 857-862.
13. Roy, L., Buard, V., Delbos, M., Durand, V., Paillole, N., Gregoire, E., Voisin, P. (2004) International intercomparison for criticality dosimetry: the case of biological dosimetry. Radiat. Prot. Dos. 110 (1-4): 471-476.
14. Hayata, I., Kanda, R., Minamihisamatsu, M., Furukawa, M., Sasaki, M.S. (2001) Cytogenetical Dose Estimation of 3 Severely Exposed Patients in the JCO Criticality Accident in Tokai-mura. J. Radiat. Res. 42: S149-S155.
15. Murata, H., Akashi, M. (2002) The report of the criticality accident in a uranium conversion test plant in Tokai-mura, National Institute of Radiological Sciences (NIRS), Chiba.