Nicotinic acetylcholine receptor antagonistic property of the selective dopamine uptake inhibitor, GBR-12909 in rat hippocampal slices

Neuroscience

Volumn 145, Issue 1, 2007, Pages 344-349

  Szasz, B K ^a   Vizi, E S ^a   Kiss, J P ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

GBR 12909; monoamine uptake systems; nicotinic acetylcholine receptors; selective dopamine uptake inhibitors

Indexed keywords

NICOTINE; NICOTINIC RECEPTOR BLOCKING AGENT; NORADRENALIN; NORADRENALIN UPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SODIUM CHANNEL; SODIUM CHANNEL BLOCKING AGENT; TETRODOTOXIN; TRITIUM; VANOXERINE;

ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CHOLINERGIC RECEPTOR BLOCKING; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG SELECTIVITY; ELECTROSTIMULATION; HIPPOCAMPUS; IC 50; ISOTOPE LABELING; MALE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT;

ANESTHETICS, LOCAL; ANIMALS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; MALE; NICOTINE; NICOTINIC ANTAGONISTS; PIPERAZINES; RATS; RATS, WISTAR; TETRODOTOXIN; TRITIUM;

EID: 33846867713     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.11.032     Document Type: Article

References (36)

1. Andersen P.H. The dopamine inhibitor GBR-12909: selectivity and molecular mechanism of action. Eur J Pharmacol 166 (1989) 493-504
2. Aronstam R.S. Interactions of tricyclic antidepressants with a synaptic ion channel. Life Sci 28 (1981) 59-64
3. Bolden-Watson C., and Richelson E. Blockade by newly-developed antidepressants of biogenic amine uptake into rat brain synaptosomes. Life Sci 52 (1993) 1023-1029
4. Carvelli L., McDonald P.W., Blakely R.D., and Defelice L.J. Dopamine transporters depolarize neurons by a channel mechanism. Proc Natl Acad Sci U S A 101 (2004) 16046-16051
5. DeFelice L.J., and Blakely R.D. Pore models for transporters?. Biophys J 70 (1996) 579-580
6. Fryer J.D., and Lukas R.J. Antidepressants noncompetitively inhibit nicotinic acetylcholine receptor function. J Neurochem 72 (1999) 1117-1124
7. Fryer J.D., and Lukas R.J. Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. J Pharmacol Exp Ther 288 (1999) 88-92
8. Galli A., DeFelice L.J., Duke B.J., Moore K.R., and Blakely R.D. Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants. J Exp Biol 198 (1995) 2197-2212
9. Garcia-Colunga J., Awad J.N., and Miledi R. Blockage of muscle and neuronal nicotinic acetylcholine receptors by fluoxetine (Prozac). Proc Natl Acad Sci U S A 94 (1997) 2041-2044
10. Harley C.W. Norepinephrine and dopamine as learning signals. Neural Plast 11 (2004) 191-204
11. Hennings E.C., Kiss J.P., De Oliveira K., Toth P.T., and Vizi E.S. Nicotinic acetylcholine receptor antagonistic activity of monoamine uptake blockers in rat hippocampal slices. J Neurochem 73 (1999) 1043-1050
12. Hennings E.C., Kiss J.P., and Vizi E.S. Nicotinic acetylcholine receptor antagonist effect of fluoxetine in rat hippocampal slices. Brain Res 759 (1997) 292-294
13. Hyttel J. Citalopram-pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry 6 (1982) 277-295
14. Izaguirre V., Fernandez-Fernandez J.M., Cena V., and Gonzalez-Garcia C. Tricyclic antidepressants block cholinergic nicotinic receptors and ATP secretion in bovine chromaffin cells. FEBS Lett 418 (1997) 39-42
15. Kiss J.P., Windisch K., Balla A., Sershen H., and Lajtha A. Dual effect of DMPP on the resting release of noradrenaline from rat hippocampal slices. Brain Res Bull 43 (1997) 257-262
16. Kiss J.P., Windisch K., De Oliveira K., Hennings E.C., Mike A., and Szasz B.K. Differential effect of nicotinic agonists on the [3H]norepinephrine release from rat hippocampal slices. Neurochem Res 26 (2001) 943-950
17. Larsson H.P., Picaud S.A., Werblin F.S., and Lecar H. Noise analysis of the glutamate-activated current in photoreceptors. Biophys J 70 (1996) 733-742
18. Lee E.H., and Ma Y.L. Amphetamine enhances memory retention and facilitates norepinephrine release from the hippocampus in rats. Brain Res Bull 37 (1995) 411-416
19. Lerner-Marmarosh N., Carroll F.I., and Abood L.G. Antagonism of nicotine's action by cocaine analogs. Life Sci 56 (1995) PL67-PL70
20. Lester H.A., Cao Y., and Mager S. Listening to neurotransmitter transporters. Neuron 17 (1996) 807-810
21. Maggi L., Palma E., Miledi R., and Eusebi F. Effects of fluoxetine on wild and mutant neuronal alpha 7 nicotinic receptors. Mol Psychiatry 3 (1998) 350-355
22. Mike A., Karoly R., Vizi E.S., and Kiss J.P. Inhibitory effect of the DA uptake blocker GBR-12909 on sodium channels of hippocampal neurons. Neuroreport 14 (2003) 1945-1949
23. Mike A., Karoly R., Vizi E.S., and Kiss J.P. A novel modulatory mechanism of sodium currents: frequency-dependence without state-dependent binding. Neuroscience 125 (2004) 1019-1028
24. Miller D.K., Wong E.H., Chesnut M.D., and Dwoskin L.P. Reboxetine: functional inhibition of monoamine transporters and nicotinic acetylcholine receptors. J Pharmacol Exp Ther 302 (2002) 687-695
25. Park T.J., Shin S.Y., Suh B.C., Suh E.K., Lee I.S., Kim Y.S., and Kim K.T. Differential inhibition of catecholamine secretion by amitriptyline through blockage of nicotinic receptors, sodium channels, and calcium channels in bovine adrenal chromaffin cells. Synapse 29 (1998) 248-256
26. Sershen H., Balla A., Lajtha A., and Vizi E.S. Characterization of nicotinic receptors involved in the release of noradrenaline from the hippocampus. Neuroscience 77 (1997) 121-130
27. Slemmer J.E., Martin B.R., and Damaj M.I. Bupropion is a nicotinic antagonist. J Pharmacol Exp Ther 295 (2000) 321-327
28. Sonders M.S., and Amara S.G. Channels in transporters. Curr Opin Neurobiol 6 (1996) 294-302
29. Sonders M.S., Zhu S.J., Zahniser N.R., Kavanaugh M.P., and Amara S.G. Multiple ionic conductances of the human dopamine transporter: the actions of dopamine and psychostimulants. J Neurosci 17 (1997) 960-974
30. Srikumar B.N., Raju T.R., and Shankaranarayana Rao B.S. The involvement of cholinergic and noradrenergic systems in behavioral recovery following oxotremorine treatment to chronically stressed rats. Neuroscience 143 (2006) 679-688
31. Su C., and Bevan J.A. Blockade of the nicotine-induced norepinephrine release by cocaine, phenoxybenzamine and desipramine. J Pharmacol Exp Ther 175 (1970) 533-540
32. Sulzer D., and Galli A. Dopamine transport currents are promoted from curiosity to physiology. Trends Neurosci 26 (2003) 173-176
33. Szasz B.K., Mayer A., Zsilla G., Lendvai B., Vizi E.S., and Kiss J.P. Carrier-mediated release of monoamines induced by the nicotinic acetylcholine receptor agonist DMPP. Neuropharmacology 49 (2005) 400-409
34. Vizi E.S., Harsing Jr. L.G., Zimanvi I., and Gaal G. Release and turnover of noradrenaline in isolated median eminence: lack of negative feedback modulation. Neuroscience 16 (1985) 907-916
35. Vizi E.S., Sershen H., Balla A., Mike A., Windisch K., Juranyi Z., and Lajtha A. Neurochemical evidence of heterogeneity of presynaptic and somatodendritic nicotinic acetylcholine receptors. Ann N Y Acad Sci 757 (1995) 84-99
36. Wong D.T., Bymaster F.P., and Engleman E.A. Prozac (fluoxetine, Lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication. Life Sci 57 (1995) 411-441