Synthesis and evaluation of a small library of graftable thrombin inhibitors derived from (l)-arginine

European Journal of Medicinal Chemistry

Volumn 42, Issue 1, 2007, Pages 37-53

  Salvagnini, Claudio ^a   Gharbi, Sonia ^a   Boxus, Thierry ^b   Marchand Brynaert, Jacqueline ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b Mettler Toledo Schweiz GmbH   (Switzerland)

Author keywords

Arginine derivatives; Blood compatible materials; Graftable inhibitors; Thrombin inhibitors

Indexed keywords

ARGININE DERIVATIVE; POLYETHYLENE TEREPHTHALATE; THROMBIN; THROMBIN INHIBITOR; TOSYLARGININE METHYL ESTER;

ARTICLE; BIOCOMPATIBILITY; BLOOD CLOTTING; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; EVALUATION; HUMAN; HUMAN TISSUE; INFRARED SPECTROSCOPY; NORMAL HUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STRUCTURE ANALYSIS; X RAY PHOTOELECTRON SPECTROSCOPY;

AMIDES; ANTICOAGULANTS; ARGININE; BLOOD COAGULATION; HUMANS; KINETICS; MEMBRANES, ARTIFICIAL; PIPERAZINES; POLYETHYLENE TEREPHTHALATES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 33846849486     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.07.010     Document Type: Article

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