Anticoagulant effects of sulphonated polpisoprenes

Biomaterials

Volumn 19, Issue 7-9, 1998, Pages 745-750

  Tamada, Yasushi ^a,d   Murata, Mitsuhiro ^a   Makino, Kenya ^a   Yoshida, Yoshinori ^a   Yoshida, Tadao ^b   Hayashi, Toshio ^c  

^a Japan Synthetic Rubber Co Ltd   (Japan)

^b Shiga Hospital   (Japan)

^c Osaka Prefecture University   (Japan)

^d NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

Author keywords

Anticoagulant; Fibrinogen; Polyisoprenes; Sulphonates

Indexed keywords

BIOASSAY; BLOOD; MOLECULAR WEIGHT; POLYISOPRENES; PROTEINS; SULFUR COMPOUNDS; SYNTHESIS (CHEMICAL);

ANTICOAGULANT ACTIVITY; FIBRINOGEN;

BIOMATERIALS;

ISOPRENE; POLYMER; SULFONIC ACID DERIVATIVE;

ANTICOAGULATION; ARTICLE; BLOOD CLOTTING TIME; MOLECULAR WEIGHT; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME;

ANIMALS; ANTICOAGULANTS; BLOOD COAGULATION; MOLECULAR WEIGHT; POLYPROPYLENES; PROTHROMBIN TIME; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONIC ACIDS; THROMBIN TIME;

EID: 0032052115     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(97)00207-X     Document Type: Article

References (20)

1. [1] Yen SPS, Rembaum P. Complexes of heparin with elastomeric positive polyelectrolytes. J Biomed Mater Res 1971; Symp. No. 1: 83-98.
2. [2] Jozefowicz M, Jozefonvicz J. Antithrombogenic polymers. Pure Appl Chem 1984;56:1335-44.
3. [3] Rhodes NP, Williams DF. Plasma recalcification as a measure of contact phase activation and heparinization efficacy after contact with biomaterials. Biomaterials 1994;15:35-37.
4. [4] Rosenberg RD. Heparin, antithrombin and abnormal clotting. Ann Rev Med 1978;29:367-78.
5. [5] Lovelock JE, Porterfield JS. Blood coagulation: its prolongation in vessels with negatively-charged surfaces. Nature Lond 1951; 167:39-40.
6. [6] Gregor HP. Anticoagulant activity of sulfonate polymers and copolymers. In: Gregor HP, editor. Biomedical applications of polymers polymer science and technology, vol. 7. New York: Plenum Press, 1975:51-56.
7. [7] Fougnot C, Jozefonvicz J, Samama M, Bara L. New heparin-like insoluble materials: Part I. Ann Biomed Eng 1979;7:429-39.
8. [8] Mauzac M, Aubert N, Jozefonvicz J. Antithrombic activity of some polysaccharide resins. Biomaterials 1982;3:221-24.
9. [9] Kanmangne FM, Labarre D, Serne H, Jozefowicz M. Heparin-like activity of insoluble sulphonated poystyrene resins. Part I: influence of the surface density, nature and binding of substituted anionic groups. Biomaterials 1985;6:297-302.
10. [10] Douzon C, Kanmangne FM, Serne H, Labarre D, Jozefowicz M. Heparin-like activity of insoluble sulphonated polystyrene resins. Part III: binding of dicarboxylic amino acids. Biomaterials 1987;8:190-94.
11. [11] Okkema AZ, Cooper SL. Effect of carboxylate and/or sulphonate ion incorporation on the physical and blood-contacting properties of a polyetherurethane. Biomaterials 1991;12:668-76.
12. [12] Okkema AZ, Visser SA, Cooper SL. Physical and blood-contacting properties of polyurethanes based on a sulfonic acid-containing diol chain extender. J Biomed Mater Res 1991; 25:1371-95.
13. [13] Grasel TG, Cooper SL. Properties and biological interactions of Polyurethane anionomers: effect of sulfonate incorporation. J Biomed Mater Res 1989;23:311-38.
14. [14] Silver JH, Hart AP, Williams EC. Anticoagulant effects of sulphonated polyurethanes. Biomaterials 1992;13:339-44.
15. [15] Csomor K, Karpati E, Nagy M, Gyorgyi-Edelenyi J, Machovich R. Blood coagulation is inhibited by sulphated copolymers of vinyl alcohol and acrylic acid under in vitro as well as in vivo conditions. Thromb Res 1994;74:389-98.
16. [16] van der Does L, Hofman J, van Utteren TEC. Reaction of n-chlorosulfonyl isocyanate with unsaturated polymers. Route to a synthesis of polyampholytes. J Polym Sci Polym Lett Edn 1973;11:169-72.
17. [17] van der Does L, van Duijl JF, Sederel LC, Bantjes A. Modified polymers from cis-1,4-polyisoprene. J Polym Sci Polym Lett Edn 1980;18:53-58.
18. [18] Beugeling T, van der Does L, Bantjes A, Sederel, WL. Antithrombin activity of a polyelectrolyte synthesized from cis-1,4-polyisoprene. J Biomed Mater Res 1974;8:375-79.
19. [19] van der Does L, Beugeling T, Froehling PE, Bantjes A. Synthetic polymers with anticoagulant activity. J Polym Sci Polym Symp 1979;66:337-48.
20. [20] Morse EE, Panek S, Menga R. Automated fibrinogen determination. Amer J Clin Path 1971;55:671-76.