Reversible glutathiolation of caspase-3 by glutaredoxin as a novel redox signaling mechanism in tumor necrosis factor-α-induced cell death

Circulation Research

Volumn 100, Issue 2, 2007, Pages 152-154

  Sykes, Michelle C ^a   Mowbray, Amy L ^a   Jo, Hanjoong ^a,b  

^a Emory University   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspase 3; Glutaredoxin; Glutathiolation; Reactive oxygen species; TNF

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; DNA FRAGMENT; GLUTAREDOXIN; GLUTATHIONE; GLUTATHIONE REDUCTASE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; MANGANESE SUPEROXIDE DISMUTASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMALL INTERFERING RNA; SUCCINATE DEHYDROGENASE (UBIQUINONE); TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2;

APOPTOSIS; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CELL DEATH; DISSOCIATION; EDITORIAL; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE OVEREXPRESSION; MECHANOTRANSDUCTION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; WILD TYPE;

ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 8; ENZYME PRECURSORS; GLUTATHIONE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; NF-KAPPA B; OXIDATION-REDUCTION; OXIDOREDUCTASES; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33846849238     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000258171.08020.72     Document Type: Editorial

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