Herpes simplex virus-type 2 infectivity and agents that block gap junctional intercellular communication

Virus Research

Volumn 124, Issue 1-2, 2007, Pages 212-219

  Knabb, Maureen T ^a   Danielsen, Casey A ^a   McShane Kay, Kerry ^a   Mbuy, Gustave K N ^a   Woodruff, Richard I ^a  

^a WEST CHESTER UNIVERSITY   (United States)

Author keywords

Connexin 43; Gap junctions; H7; HSV 2; Protein kinase C

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; DYE; GAP JUNCTION PROTEIN; GLYCYRRHETINIC ACID; NUCLEAR PROTEIN; OCTANOL; PROTEIN KINASE C INHIBITOR; SERINE; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; EPITHELIUM; GAP JUNCTION; HERPES SIMPLEX VIRUS 2; IMMUNOFLUORESCENCE; LIVER; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; REDUCTION KINETICS; VIRUS INFECTIVITY; WESTERN BLOTTING;

ANIMALS; ANTIVIRAL AGENTS; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE STRUCTURES; CONNEXIN 43; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCENT ANTIBODY TECHNIQUE; FLUORESCENT DYES; GAP JUNCTIONS; GLYCYRRHETINIC ACID; HEPATOCYTES; HERPESVIRUS 2, HUMAN; INTERCELLULAR JUNCTIONS; NUCLEAR PROTEINS; OCTANOLS; PHOSPHORYLATION; PLAQUE ASSAY; PROTEIN KINASE INHIBITORS; RATS; STAUROSPORINE;

HUMAN HERPESVIRUS 2; RATTUS;

EID: 33846834112     PISSN: 01681702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.virusres.2006.11.006     Document Type: Article

References (44)

1. Atkinson M.M., Menko A.S., Johnson R.G., Sheppard J.R., and Sheridan J.D. Rapid and reversible reduction of junctional permeability in cells infected with a temperature-sensitive mutant of avian sarcoma virus. J. Cell Biol. 91 (1981) 573-578
2. Brissette J.L., Kumar N.K., Gilula N.B., and Dotto G.P. The tumor promoter 12-o-tetradecanoylphorbol-13-acetate and the ras oncogene module expression and phosphorylation of gap junction proteins. Mol. Cell. Biol. 11 (1991) 5364-5371
3. Castagnino C.G., Yakisich J.S., Iacono R.F., Berria M.I., and Idoyaga-Vargas V. Growth inhibition of herpes simplex virus-type 1 in calphostin C-treated astrocytes. Intervirology 38 6 (1995) 332-338
4. Chanson M., Bruzzone R., Bosco D., and Meda P.J. Effects of n-alcohols on junctional coupling and amylase secretion of pancreatic acinar cells. J. Cell. Physiol. 139 (1989) 147-156
5. Constantinescu S.N., Cernescu C.D., and Popescu L.M. Effects of protein kinase C inhibitors on viral entry and infectivity. FEBS Lett. 292 1-2 (1991) 31-33
6. Cotrina M., Lin J.H., Alves-Rodrigues A., Liu S., Li J., Azmi-Ghadimi H., Kang J., Naus C.C.G., and Nedergaard M. Connexins regulate calcium signaling by controlling ATP release. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 15735-15740
7. Crow D.S., Beyer E.C., Paul D.L., Kobe S.S., and Lau A.F. Phosphorylation of connexin43 gap junction protein in uninfected and Rous Sarcoma Virus-transformed mammalian fibroblasts. Mol. Cell. Biol. 10 (1990) 1754-1763
8. Cruciani V., and Mikalsen S.O. Connexins, gap junctional intercellular communication and kinases. Biol. Cell 94 (2002) 433-443
9. Danave R.I., Tiffany-Castiglioni E., Zenger E., Barhoumi R., Burghardt R.C., and Collisson E.W. Feline immunodeficiency virus decreases cell-cell communication and mitochondrial membrane potential. J. Virol. 68 (1994) 6745-6750
10. Davidson J.S., Baumgarten I.M., and Harley E.H. Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid. Biochem. Biophys. Res. Commun. 134 1 (1986) 29-36
11. Davidson J.S., and Baumgarten I.M. Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. J. Pharmacol. Exp. Ther. 246 3 (1988) 1104-1107
12. De Mello W.C. Increase in junctional conductance caused by isoproterenol in heart cell pairs is suppressed by cAMP-dependent protein-kinase inhibitor. Biochem. Biophys. Res. Commun. 154 2 (1988) 509-514
13. Duthe F., Dupont E., Verrecchia F., Plaisance I., Severs N.J., Sarrouilhe D., and Herve J.C. Dephosphorylation agents depress gap junctional communication between rat cardiac cells without modifying the connexin43 phosphorylation degree. Gen. Physiol. Biophys. 19 4 (2000) 441-449
14. el-Fouly M.H., Trosko J.E., and Chang C.C. Scrape-loading and dye transfer. A rapid and simple technique to study gap junctional intercellular communication. Exp. Cell Res. 168 (1987) 422-430
15. Ennaji M.M., Schwartz J.L., Mealing G., Belbaraka L., Parker C., Parentaux M., Jouishomme H., Arella M., Whitfield J.F., and Phipps J. Alterations in cell-cell communication in human papillomavirus type 16 (HPV16) transformed rat myoblasts. Cell. Mol. Biol. 41 (1995) 481-498
16. Esinduy C.B., Chang C.C., Trosko J.E., and Ruch R.J. In vitro growth inhibition of neoplastically transformed cells by non-transformed cells: requirement for gap junctional intercellular communication. Carcinogenesis 16 4 (1995) 915-921
17. Faccini A.M., Cairney M., Ashrafi B.H., Finbow M.E., Campo M.S., and Pitts J.D. The bovine papillomavirus type E8 protein binds to ductin and causes loss of gap junctional intercellular communication in primary fibroblasts. J. Virol. 70 (1996) 9041-9045
18. Filson A.J., Azarnia R., Beyer E.C., Loewenstein W.R., and Brugge J.S. Tyrosine phosphorylation of a gap junction protein correlates with inhibition of cell-to-cell communication. Cell Growth Differ. 1 (1990) 661-668
19. Fischer N.O., Mbuy G.N.K., and Woodruff R.I. HSV-2 disrupts gap junctional intercellular communication between mammalian cells in vitro. J. Virol. Methods 91 (2001) 157-166
20. Fletcher W.H., Shiu W.W., Ishida T.A., Haviland D.L., and Ware C.F. Resistance to the cytolytic action of lymphotoxin and tumor necrosis factor coincides with the presence of gap junctions uniting target cells. J. Immunol. 139 (1987) 956-962
21. Goldstein D.J., Finbow M.E., Andersson T., McLean P., Smith K., Bubb V., and Schlegel R. Bovine papillomavirus E5 oncoprotein binds to the 16K component of vacuolar H(+)-ATPases. Nature 352 (1991) 347-349
22. Guan X., Wilson S., Schlender K.K., and Ruch R.J. Gap-junction disassembly and connexin 43 dephosphorylation induced by 18β-glycyrrhetinic acid. Mol. Carcinog. 16 (1996) 157-164
23. Guan X., Cravatt B.F., Ehring G.R., Hall J.E., Boger D.L., Lerner R.A., and Gilula N.B. The sleep-inducing lipid oleamide deconvolutes gap junction communication and calcium wave transmission in glial cells. J. Cell Biol. 139 7 (1997) 1785-1792
24. Herve J.C., Plaisance I., Loncarek J., Duthe F., and Sarrouilhe D. Is the junctional uncoupling elicited in rat ventricular myocytes by some dephosphorylation treatments due to changes in the phosphorylation status of Cx43?. Eur. Biophys. J. 33 3 (2004) 201-210
25. Hidaka H., Inagaki M., Kawamoto S., and Sasaki Y. Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23 (1984) 5036-5041
26. Jou Y.S., Layhe B., Matesic D.F., Chang C.C., de Feijter A.W., Lockwood L., Welsch C.W., Klaunig J.E., and Trosko J.E. Inhibition of gap junctional intercellular communication and malignant transformation of rat liver epithelial cells by neu oncogene. Carcinogenesis 16 (1995) 311-317
27. Lampe P.D., and Lau A.F. Regulation of gap junctions by phosphorylation of connexins. Arch. Biochem. Biophys. 384 (2000) 205-215
28. Lowenstein W.R. Regulation of cell-to-cell communication by phosphorylation. Biochem. Soc. Symp. 50 (1985) 43-58
29. Moreno A.P., Saez J.C., Fishman G.I., and Spray D.C. Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation. Circ. Res. 74 6 (1994) 1050-1057
30. Musee J., Mbuy G.N.K., and Woodruff R.I. Antiviral agents alter ability of HSV-2 to disrupt gap junctional intercellular communication between mammalian cells in vitro. Antiviral Res. 56 (2002) 143-151
31. Musil L.S., and Goodenough D.A. Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques. J. Cell Biol. 115 (1991) 1357-1374
32. Muranyi W., Haas J., Wagner M., Krohne G., and Koszinowski U.H. Cytomegalovirus recruitment of cellular kinases to dissolve the nuclear lamina. Science 297 5582 (2002) 778-779
33. Opsahl H., and Rivedal E. Quantitative determination of gap junction intercellular communication by scrape loading and image analysis. Cell Adhes. Commun. 7 (2000) 367-375
34. Park R., and Baines J.D. Herpes simplex virus type 1 infection induces activation and recruitment of protein kinase C to the nuclear membrane and increased phosphorylation of lamin B. J. Virol. 80 1 (2006) 494-504
35. Richards T.S., Dunn C.A., Carter W.G., Usui M.L., Olerud J.E., and Lampe P.D. Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368. J. Cell Biol. 167 3 (2004) 555-562
36. Saez J.C., Nairn A.C., Czernik A.J., Fishman G.I., Spray D.C., and Hertzberg E.L. Phosphorylation of connexin43 and the regulation of neonatal rat, cardiac myocyte gap junctions. J. Mol. Cell. Cardiol. 29 8 (1997) 2131-2145
37. Saez J.C., Berthoud V.M., Branes M.C., Martinez A.D., and Beyer E.C. Plasma membrane channels formed by connexins: their regulation and functions. Physiol. Rev. 83 4 (2003) 1359-1400
38. Schang L.M., Bantly A., Knockaert M., Shaheen F., Meijer L., Malim M.H., Gray N.S., and Schaffer P.A. Pharmacological cyclin-dependent kinase inhibitors inhibit replication of wild-type and drug-resistant strains of herpes simplex virus and human immunodeficiency virus type 1 by targeting cellular, not viral, proteins. J. Virol. 76 15 (2002) 7874-7882
39. Spray D.C., Chanson M., Moreno A.P., Dermietzel R., and Meda P. Distinctive gap junction channel types connect WB cells, a clonal cell line derived from rat liver. Am. J. Physiol. 260 3 Pt 1 (1991) C513-C527
40. Stuurman N. Identification of a conserved phosphorylation site modulating nuclear lamin polymerization. FEBS Lett. 401 2-3 (1997) 171-174
41. Walro D.G., and Rosenthal K.S. The antiviral xanthate compound D609 inhibits herpes simplex virus type 1 replication and protein phosphorylation. Antiviral Res. 36 (1997) 63-72
42. Warn-Cramer B.J., and Lau A.F. Regulation of gap junctions by tyrosine protein kinases. Biochim. Biophys. Acta Biomembr. 1662 (2004) 81-96
43. Yura Y., Yoshida H., and Sato M. Inhibition of herpes simplex virus replication by genistein, an inhibitor of protein-tyrosine kinase. Arch. Virol. 132 (1993) 451-461
44. Yura Y., Kusaka J., Tsujimoto H., Yoshioka Y., Yoshida H., and Sato M. Effects of protein tyrosine kinase inhibitors on the replication of herpes simplex virus and the phosphorylation of viral proteins. Intervirology 40 (1997) 7-14