Enzymatic properties and localization of motopsin (PRSS12), a protease whose absence causes mental retardation

Brain Research

Volumn 1136, Issue 1, 2007, Pages 1-12

  Mitsui, Shinichi ^a   Yamaguchi, Nozomi ^b   Osako, Yoji ^a   Yuri, Kazunari ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Cerebral cortex; Neurotrypsin; Serine protease; Tissue plasminogen activator

Indexed keywords

(4 AMIDOPHENYL)METHANESULFONYL FLUORIDE; APROTININ; BENZYLOXYCARBONYLPHENYLALANYLARGINYL 4 METHYLCOUMARYL 7 AMIDE; COUMARIN DERIVATIVE; IMMUNOGLOBULIN G ANTIBODY; LEUPEPTIN; MESYLIC ACID DERIVATIVE; MOTOPSIN; PROTEINASE; SERINE PROTEINASE; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CINGULATE GYRUS; CONTROLLED STUDY; DENDRITE; ENZYME ACTIVITY; FETUS; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LIMBIC SYSTEM; MENTAL DEFICIENCY; MOUSE; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PYRAMIDAL NERVE CELL; PYRIFORM CORTEX;

ANIMALS; ANIMALS, NEWBORN; AXONS; BRAIN; CELLS, CULTURED; DENDRITES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MICE; MICE, INBRED C57BL; NEURONS; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; TRANSFECTION;

MUS;

EID: 33846826712     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.11.094     Document Type: Article

References (33)

1. Chen Z.-L., and Strickland S. Neuronal death in the hippocampus is promoted by plasmin-catalyzed degradation of laminin. Cell 91 (1997) 917-925
2. Gingrichi M.B., Junge C.E., Lyuboslavsky P., and Traynelis S.F. Potentiation of NMDA receptor function by the serine protease thrombin. J. Neurosci. 20 (2000) 4582-4595
3. Goslin K., Asmussen H., and Banker G. Rat Hippocampal Neurons in Low-Density Culture: From the Culturing Nerve Cells (1988), MIT Press, London 339-370
4. Gschwend T.P., Krueger S.R., Kozlov S.V., Wolfer D.P., and Sonderegger P. Neurotrypsin, a novel multidomain serine protease expressed in the nervous system. Mol. Cell. Neuosci. 9 (1997) 207-219
5. Hirata A., Yoshida S., Inoue N., Matsumoto-Miyai K., Ninomiya A., Taniguchi M., Matsuyama T., Kato K., Iizasa H., Kataoka Y., Yoshida N., and Shiosaka S. Abnormalities of synapses and neurons in the hippocampus of neuropsin-deficient mice. Mol. Cell. Neuosci. 17 (2001) 600-610
6. Huang Y.-Y., Bach M.E., Lipp H.-P., Zhuo M., Wofer D.P., Hawkins R.D., Schoonjans L., Kandel E.R., Godfraind J.-M., Mulligan R., Collen D., and Carmeliet P. Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc. Natl. Acad. Sci. U. S. A. 93 (1996) 8699-8704
7. Iijima N., Tanaka M., Mitsui S., Yamamura Y., Yamaguchi N., and Ibata Y. Expression of a serine protease (motopsin PRSS12) mRNA in the mouse brain: in situ hybridization histochemical study. Mol. Brain Res. 66 (1999) 141-149
8. Mandani R., Hulo S., Toni N., Madani H., Steimer T., Dominique M., and Vassalli J.-D. Enhanced hippocampal long-term potentiation and learning by increased neuronal expression of tissue-type plasminogen activator in transgenic mice. EMBO J. 18 (1999) 3007-3012
9. Matsumoto-Miyai K., Ninomiya A., Yamasaki H., Tamura H., Nakamura Y., and Shiosaka S. NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin. J. Neurosci. 23 (2003) 7727-7736
10. Mitsui S., Tsuruoka N., Yamashiro K., Nakazato H., and Yamaguchi N. A novel form of human neuropsin, a brain-related serine protease, is generated by alternative splicing and is expressed preferentially in human adult brain. Eur. J. Biochem. 260 (1999) 627-634
11. Mitsui S., Yamada T., Okui A., Kominami K., Uemura H., and Yamaguchi N. A novel isoform of a kallikrein-like protease, TLSP/hippostasin, (PRSS20), is expressed in the human brain and prostate. Biochem. Biophys. Res. Commun. 272 (2000) 205-211
12. Mitsui S., Okui A., Kominami K., Uemura H., and Yamaguchi N. cDNA cloning and tissue-specific splicing variants of mouse hippostasin/TLSP (PRSS20). Biochim. Biophys. Acta 1494 (2000) 206-210
13. Mitsui S., Okui A., Uemura H., Mizuno T., Yamada T., Yamamura Y., and Yamaguchi N. Decreased cerebrospinal fluid levels of neurosin (KLK6), an aging-related protease, as a possible new risk factor for Alzheimer's disease. Ann. N. Y. Acad. Sci. 977 (2002) 216-223
14. Mitsui S., Okui A., Kominami K., Konishi E., Uemura H., and Yamaguchi N. A novel serine protease highly expressed in the pancreas is expressed in various kinds of cancer cells. FEBS J. 272 (2005) 4911-4923
15. Mitsui S., Nakamura T., Okui A., Kominami K., Uemura H., and Yamaguchi N. Multiple promoters regulate tissue-specific alternative splicing of the human kallikrein gene, KLK11/hippostasin. FEBS J. 273 (2006) 3678-3686
16. Molinari F., Rio M., Meskenaite V., Férechté E.-R., Augé J., Bacq D., Briault S., Vekemans M., Munnich A., Attié-Bitach T., Sonderegger P., and Colleaus L. Truncating neurotrypsin mutation in autosomal recessive nonsyndromic mental retardation. Science 298 (2002) 1779-1781
17. Numajiri T., Mitsui S., Hisa Y., Ishida T., Nishino K., and Yamaguchi N. The expression of a motoneuron-specific serine protease, motopsin (PRSS12), after facial nerve axotomy in mice. J. Plast. Reconstr. Aesthet. Surg. 59 (2006) 393-397
18. Pittman R.N., and DiBenedetto A.J. PC12 cells overexpressing tissue plasminogen activator regenerate neurites to a greater extent and migrate faster than control cells in complex extracellular matrix. J. Neurochem. 64 (1995) 566-575
19. Sallés F.J., and Strickland S. Localization and regulation of the tissue plasminogen activator-plasmin system in the hippocampus. J. Neurosci. 22 (2002) 2125-2134
20. Sambrook J., and Russell D.W. Molecular Cloning: A Laboratory Manual. 3rd ed. (2001), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
21. Seeds N.W., Basham M.E., and Haffke S.P. Neuronal migration is retarded in mice lacking the tissue plasminogen activator gene. Proc. Natl. Acad. Sci. U. S. A. 96 (1999) 14118-14123
22. Shin C.Y., Kundel M., and Wells D.G. Rapid, activity-induced increase in tissue plasminogen activator is mediated by metabotropic glutamate receptor-dependent mRNA translation. J. Neurosci. 24 (2004) 9425-9433
23. Shiosaka S., and Yoshida S. Synaptic microenvironments-structural plasticity, adhesion molecules, proteases and their inhibitors. Neurosci. Res. 37 (2000) 85-89
24. Tomimatsu Y., Idemoto S., Moriguchi S., Watanabe S., and Nakanishi H. Proteases involved in long-term potentiation. Life Sci. 72 (2002) 355-361
25. Tsirka S.E. Tissue plasminogen activator as a modulator of neuronal survival and function. Biochem. Soc. Trans. 30 (2002) 222-225
26. Tsirka S., Gualandris A., Amaral D., and Strickland S. Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature 377 (1995) 340-344
27. Tsirka S., Rogove A., Bugge T., Degen J., and Strickland S. An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J. Neurosci. 17 (1997) 543-552
28. Watanabe Y., Okui A., Mitsui S., Kawarabuki K., Yamaguchi T., Uemura H., and Yamaguchi N. Molecular cloning and tissue-specific expression of mouse spinesin, a type II transmembrane serine protease 5. Biochem. Biophys. Res. Commun. 324 (2004) 333-340
29. Wolfer D.P., Lang R., Cinelli P., Madani R., and Sonderegger P. Multiple roles of neurotrypsin in tissue morphogenesis and nervous system development suggested by the mRNA expression pattern. Mol. Cell. Neuosci. 18 (2001) 407-433
30. Wu Y.P., Siao C.-J., Lu W., Sung T.-C., Frohman M.A., Milev P., Bugge T.H., Degen J.L., Margolis R.U., and Tsirka S.E. The tissue plasminogen activator (tPA)/plasmin extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate. J. Cell Biol. 148 (2000) 1295-1304
31. Yamaguchi N., Okui A., Yamada T., Nakazato H., and Mitsui S. Spinesin/TMPRSS5, a novel transmembrane serine protease, cloned from human spinal cord. J. Biol. Chem. 277 (2002) 6806-6812
32. Yamamura Y., Yamashiro K., Tsuruoka N., Nakazato H., Tsujimura A., and Yamaguchi N. Molecular cloning of a novel brain-specific serine protease with a kringle-like structure and three scavenger receptor cysteine-rich motifs. Biochem. Biophys. Res. Commun. 239 (1997) 386-392
33. Yamashiro K., Tsuruoka N., Kodama S., Tsujimoto M., and Yamaguchi N. Molecular cloning of a novel trypsin-like serine protease (neurosin) preferentially expressed in brain. Biochim. Biophys. Acta 1352 (1997) 11-14