Lamina propria and circulating interleukin-8 in newly and previously diagnosed pediatric inflammatory bowel disease patients

Digestive Diseases and Sciences

Volumn 52, Issue 2, 2007, Pages 365-372

  Reddy, Krishna P ^a   Markowitz, Jonathan E ^a,b   Ruchelli, Eduardo D ^a   Baldassano, Robert N ^a,b   Brown, Kurt A ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Inflammatory bowel disease; Interleukin 8; Lamina propria; Pediatric; Serum

Indexed keywords

INTERLEUKIN 8;

ADOLESCENT; ADULT; ARTICLE; CHILD; COLITIS; COLON BIOPSY; CONTROLLED STUDY; CORRELATION ANALYSIS; CROHN DISEASE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; ILEUM; LAMINA PROPRIA; MALE; ORGAN CULTURE; PRIORITY JOURNAL; SUPERNATANT; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; COLITIS, ULCERATIVE; COLON; CROHN DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; ILEUM; INFLAMMATORY BOWEL DISEASES; INTERLEUKIN-8; INTESTINAL MUCOSA; LINEAR MODELS; MALE; MUCOUS MEMBRANE; ORGAN CULTURE TECHNIQUES; PHILADELPHIA; SEVERITY OF ILLNESS INDEX;

EID: 33846805981     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-006-9322-y     Document Type: Article

References (33)

1. Seidman E (1998) Etiopathogenesis of inflammatory bowel disease: a pediatric perspective. Inflamm Bowel Dis 4:204-209
2. Gross V, Andus T, Caesar I, et al. (1992) Evidence for continuous stimulation of interleukin-6 production in Crohn's disease. Gastroenterology 102:514-519
3. Ishiguro Y (1999) Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis. J Gastroenterol 34:66-74
4. Reimund JM, Wittersheim C, Dumont S, et al. (1996) Mucosal inflammatory cytokine production by intestinal biopsies in patients with ulcerative colitis and Crohn's disease. J Clin Immunol 16:144-150
5. Radford-Smith G, Jewell DP (1996) Cytokines and inflammatory bowel disease. Baillieres Clin Gastroenterol 10:151-164
6. Raab Y, Gerdin B, Ahlstedt S, et al. (1993) Neutrophil mucosal involvement is accompanied by enhanced local production of interleukin-8 in ulcerative colitis. Gut 34:1203-1206
7. Nielsen OH, Rudiger N, Gaustadnes M, et al. (1997) Intestinal interleukin-8 concentration and gene expression in inflammatory bowel disease. Scand J Gastroenterol 32:1028-1034
8. Mazzucchelli L, Hauser C, Zgraggen K, et al. (1994) Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am J Pathol 144:997-1007
9. Daig R, Rogler G, Aschenbrenner E, et al. (2000) Human intestinal epithelial cells secrete interleukin-1 receptor antagonist and interleukin-8 but not interleukin-1 or interleukin-6. Gut 46:350-358
10. Grimm MC, Elsbury SK, Pavli P, et al. (1996) Interleukin 8: cells of origin in inflammatory bowel disease. Gut 38:90-98
11. Wolff B, Burns AR, Middleton J, et al. (1998) Endothelial cell "memory" of inflammatory stimulation: human venular endothelial cells store interleukin 8 in Weibel-Palade bodies. J Exp Med 188:1757
12. Eckmann L, Jung H, Schurer-Maly C, et al. (1993) Differential cytokine expression by human intestinal epithelial cell lines: Regulated expression of interleukin 8. Gastroenterology 105:1689-1697
13. Gross V, Andus T, Daig R, et al. (1995) Regulation of interleukin-8 production in a human colon epithelial cell line (HT-29). Gastroenterology 108:653-661
14. Schuerer-Maly CC, Eckmann L, Kagnoff MF, et al. (1994) Colonic epithelial cell lines as a source of interleukin-8: stimulation by inflammatory cytokines and bacterial lipopolysaccharide. Immunology 81:85-91
15. Daig R, Andus T, Aschenbrenner E, et al. (1996) Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease. Gut 38:216-222
16. Ina K, Kusugami K, Yamaguchi T, et al. (1997) Mucosal interleukin-8 is involved in neutrophil migration and binding to extracellular matrix in inflammatory bowel disease. Am J Gastroenterol 92:1342-1346
17. Mahida YR, Ceska M, Effenberger F, et al. (1992) Enhanced synthesis of neutrophil-activating peptide-1/interleukin-8 in active ulcerative colitis. Clin Sci (Lond) 82:273-275
18. Katsuta T, Lim C, Shimoda K, et al. (2000) Interleukin-8 and SDF1-[alpha] mRNA expression in colonic biopsies from patients with inflammatory bowel disease. Am J Gastroenterol 95:3157-3164
19. Gibson P, Rosella O (1995) Interleukin 8 secretion by colonic crypt cells in vitro: response to injury suppressed by butyrate and enhanced in inflammatory bowel disease. Gut 37:536-543
20. Imada A, Ina K, Shimada M, et al. (2001) Coordinate upregulation of interleukin-8 and growth-related gene product-alpha is present in the colonic mucosa of inflammatory bowel. Scand J Gastroenterol 36:854-864
21. Uguccioni M, Gionchetti P, Robbiani DF, et al. (1999) Increased expression of IP-10, IL-8, MCP-1, and MCP-3 in ulcerative colitis. Am J Pathol 155:331
22. Desreumaux P, Brandt E, Gambiez L, et al. (1997) Distinct cytokine patterns in early and chronic ileal lesions of Crohn's disease. Gastroenterology 113:118-126
23. Brandt E, Colombel JF, Ectors N, et al. (2000) Enhanced production of IL-8 in chronic but not in early ileal lesions of Crohn's disease (CD). Clin Exp Immunol 122:180-185
24. Baldassano RN, Piccoli DA (1999) Inflammatory bowel disease in pediatric and adolescent patients. Gastroenterol Clin North Am 28:445-458
25. Brattsand R, Linden M (1996) Cytokine modulation by glucocorticoids: mechanisms and actions in cellular studies. Aliment Pharmacol Ther 10:81-92
26. Brown KA, Kriss JA, Moser CA, et al. (2000) Circulating rotavirus-specific antibody-secreting cells (ASCs) predict the presence of rotavirus-specific ASCs in the human small intestinal lamina propria. J Infect Dis 182:1039-1043
27. Brown KA, Back SJ, Ruchelli ED, et al. (2002) Lamina propria and circulating interleukin-6 in newly diagnosed pediatric inflammatory bowel disease patients. Am J Gastroenterol 97:2603-2608
28. Cole AT, Pilkington BJ, McLaughlan J, et al. (1996) Mucosal factors inducing neutrophil movement in ulcerative colitis: the role of interleukin 8 and leukotriene B4. Gut 39:248-254
29. Mitsuyama K, Toyonaga A, Sasaki E, et al. (1994) IL-8 as an important chemoattractant for neutrophils in ulcerative colitis and Crohn's disease. Clin Exp Immunol 96:432-436
30. McLaughlan JM, Seth R, Vautier G, et al. (1997) Interleukin-8 and inducible nitric oxide synthase mRNA levels in inflammatory bowel disease at first presentation. J Pathol 181:87-92
31. Arai F, Takahashi T, Furukawa K, et al. (1998) Mucosal expression of interleukin-6 and interleukin-8 messenger RNA in ulcerative colitis and in Crohn's disease. Dig Dis Sci 43:2071-2079
32. DeFelice ML, Ruchelli ED, Markowitz JE, et al. (2003) Intestinal cytokines in children with pervasive developmental disorders. Am J Gastroenterol 98:1777-1782
33. Heikenen JB, Werlin SL, Brown CW, et al. (1999) Presenting symptoms and diagnostic lag in children with inflammatory bowel disease. Inflamm Bowel Dis 5:158-160