Lack of aggregation of ischemic stroke subtypes within affected sibling pairs

Neurology

Volumn 68, Issue 6, 2007, Pages 427-431

  Wiklund, P G ^a   Brown, W M ^b   Brott, T G ^c   Stegmayr, B ^a   Brown Jr , R D ^d   Nilsson Ardnor, S ^a   Hardy, J A ^e   Kissela, B M ^f   Singleton, A ^e   Holmberg, D ^a   Rich, S S ^b   Meschia, J F ^c  

^a UMEÅ UNIVERSITY   (Sweden)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c MAYO CLINIC   (United States)

^d MAYO CLINIC   (United States)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANADA; CEREBROVASCULAR ACCIDENT; COMORBIDITY; CONTROLLED STUDY; FEMALE; GENETIC RISK; HUMAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; QUESTIONNAIRE; RISK ASSESSMENT; SIBLING; SUBARACHNOID HEMORRHAGE; SWEDEN; UNITED STATES;

ADULT; AGED; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CLUSTER ANALYSIS; COHORT STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; PREVALENCE; RISK ASSESSMENT; RISK FACTORS; SIBLINGS; SWEDEN; SWITZERLAND;

EID: 33846798051     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000252955.17126.6a     Document Type: Article

References (23)

1. Flossmann E, Schulz UG, Rothwell PM. Systematic review of methods and results of studies of the genetic epidemiology of ischemic stroke. Stroke 2004;35:212-227.
2. Polychronopoulos P, Gioldasis G, Ellul J, et al. Family history of stroke in stroke types and subtypes. J Neurol Sci 2002;195:117-122.
3. Jerrard-Dunne P, Cloud G, Hassan A, Markus HS. Evaluating the genetic component of ischemic stroke subtypes: a family history study. Stroke 2003;34:1364-1369.
4. Meschia JF, Brown RD Jr, Brott TG, Hardy J, Atkinson EJ, O'Brien PC. Feasibility of an affected sibling pair study in ischemic stroke: results of a 2-center family history registry. Stroke 2001;32:2939-2941.
5. Markus HS, Barley J, Lunt R, et al. Angiotensin-converting enzyme gene deletion polymorphism: a new risk factor for lacunar stroke but not carotid atheroma. Stroke 1995;26:1329-1333.
6. Kessler C, Spitzer C, Stauske D, et al. The apolipoprotein E and beta-fibrinogen G/A-455 gene polymorphisms are associated with ischemic stroke involving large-vessel disease. Arterioscler Thromb Vasc Biol 1997;17:2880-2884.
7. Meschia JF, Brown RD Jr, Brott TG, Chukwudelunzu FE, Hardy J, Rich SS. The Siblings With Ischemic Stroke Study (SWISS) protocol. BMC Med Genet 2002;3:1.
8. WHO MONICA Project Principal Investigators. The World Health Organization MONICA Project (Monitoring Trends and Determinants in Cardiovascular Disease): a major international collaboration. J Clin Epidemiol 1988;41:105-114.
9. Worrall BB, Chen DT, Meschia JF. Ethical and methodological issues in pedigree stroke research. Stroke 2001;32:1242-1249.
10. Meschia JF, Brott TG, Chukwudelunzu FE, et al. Verifying the stroke-free phenotype by structured telephone interview. Stroke 2000;31:1076-1080.
11. Meschia JF, Lojacono MA, Miller MJ, Brott TG, Atkinson EJ, O'Brien PC. Reliability of the questionnaire for verifying stroke-free status. Cerebrovasc Dis 2004;17:218-223.
12. Castillo PR, Brott TG, Alvarez S, Meschia JF. Creation of a bilingual Spanish-English version of the Questionnaire for Verifying Stroke-free status. Neuroepidemiology 2004;23:236-239.
13. Jones WJ, Williams LS, Meschia JF. Validating the Questionnaire for Verifying Stroke-Free Status (QVSFS) by neurological history and examination. Stroke 2001;32:2232-2236.
14. Adams HP Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial: TOAST: Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993;24:35-41.
15. Goldstein LB, Jones MR, Matchar DB, et al. Improving the reliability of stroke subgroup classification using the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) criteria. Stroke 2001;32:1091-1098.
16. Meschia JF, Barrett KM, Chukwudelunzu F, et al. Siblings With Ischemic Stroke Study (SWISS) Investigators. Interobserver agreement in the Trial of Org 10172 in Acute Stroke Treatment classification of stroke based on retrospective medical record review. J Stroke Cerebrovasc Dis 2006;15:266-272.
17. Stegmayr B, Asplund K. Measuring stroke in the population: quality of routine statistics in comparison with a population-based stroke registry. Neuroepidemiology 1992;11:204-213.
18. Nilsson-Ardnor S, Wiklund PG, Lindgren P, et al. Linkage of ischemic stroke to the PDE4D region on 5q in a Swedish population. Stroke 2005;36:1666-1671.
19. Agresti A. Categorical data analysis. New York: Wiley, 1990:353-354.
20. SAS release 8.2. (1999-2001). Cary, NC: SAS Institute.
21. Gretarsdottir S, Sveinbjornsdottir S, Jonsson HH, et al. Localization of a susceptibility gene for common forms of stroke to 5q12. Am J Hum Genet 2002;70:593-603.
22. Gretarsdottir S, Thorleifsson G, Reynisdottir ST, et al. The gene encoding phosphodiesterase 4D confers risk of ischemic stroke. Nat Genet. 2003;35:131-138 [erratum in Nat Genet 2005;37:555].
23. Schulz UG, Rothwell PM. Differences in vascular risk factors between etiological subtypes of ischemic stroke: importance of population-based studies. Stroke 2003;34:2050-2059.