Penetration of levofloxacin into the anterior chamber (aqueous humour) of the human eye after intravenous administration

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 26, Issue 2, 2007, Pages 137-140

  Garcia Vazquez E ^a   Mensa, J ^b   Sarasa, M ^b   Lopez Y ^b   Couchard, P D ^b   Soy, D ^b   Fontenla, J R ^b  

^a HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

^b HOSPITAL CLÍNIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOFLOXACIN;

ADULT; AGED; ANTERIOR EYE CHAMBER; AQUEOUS HUMOR; ARTICLE; BACTERIAL INFECTION; CATARACT EXTRACTION; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; FEMALE; GRAM NEGATIVE BACTERIUM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; AQUEOUS HUMOR; CATARACT EXTRACTION; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; OFLOXACIN;

EID: 33846795861     PISSN: 09349723     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10096-006-0241-9     Document Type: Article

References (13)

1. Axelrod JL, Klein RM, Bergen RL, Sheikh MZ (1985) Human vitreous levels of selected antistaphylococcal antibiotics. Am J Ophthalmol 100:570-575
2. Smith A, Pennefather PM, Kaye SB, Hart CA (2001) Fluoroquinolones. Place in ocular therapy. Drugs 61:747-761
3. El Baba FZ, Trousdale MD, Gandermann WJ et al (1992) Intravitreal penetration of oral ciprofloxacin in humans. Ophthalmology 99:483-486
4. Lesk MR, Ammann H, Marcil G et al (1993) The penetration of oral ciprofloxacin into the aqueous humour, vitreous and subretinal fluid of humans. Am J Ophthalmol 115:623-628
5. Ozturk F, Fortunay S, Kurt E, Ilker SS, Basci NE, Bozkurt A (1999) Penetration of topical and oral ciprofloxacin into the aqueous and vitreous humour in inflamed eyes. Retina 19:218-222
6. Morlet N, Graham GG, Gatus B, McLachlan AJ, Salonikas C, Naidoo D, Goldberg I, Man Lam C (2000) Pharmacokinetics of ciprofloxacin in the human eye: a clinical study and population pharmacokinetic analysis. Antimicrob Agents Chemother 44:1674-1679
7. Fish DN, Chow AT (1997) The clinical pharmacokinetics of levofloxacin. Clin Pharmacokinet 32:101-119
8. Pea F, Pavan F, Nascimben E et al (2003) Levofloxacin disposition in cerebrospinal fluid in patients with external ventriculostomy. Antimicrob Agents Chemother 47:3104-3108
9. Liang H, Kays MB, Sowinski KM (2002) Separation of levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin, trovafloxacin and cinoxacin by high-performance liquid chromatography: application to levofloxacin determination in human plasma. J Chromatogr B 772:53-63
10. Aaberg TM Jr, Flynn HW Jr, Schiffman J, Newton J (1998) Nosocomial acute-onset postoperative endophthalmitis survey. A 10-year review of incidence and outcomes. Ophthalmology 105:1004-1010
11. Fiscella RG, Nguyen TK, Cwik MJ, Phillpotts BA, Friedlander SM, Alter DC, Shapiro MJ, Blair NP, Gieser JP (1999) Aqueous and vitreous penetration of levofloxacin after oral administration. Ophthalmology 106:2286-2290
12. Alfaro DV, Hudson SJ, Rafanan MM, Moss ST, Levy SD (1996) The effects of trauma on the ocular penetration of intravenous ciprofloxacin. Am J Ophthalmol 122:678-683
13. García Vázquez E, Mensa J, López Y et al (2004) Penetration of linezolid into the anterior chamber (aqueous humour) of the human eye after intravenous administration. Antimicrob Agents Chemother 48:670-672