Pharmacokinetics of ciprofloxacin in the human eye: A clinical study and population pharmacokinetic analysis

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 6, 2000, Pages 1674-1679

  Morlet, Nigel ^a   Graham, Garry G ^b   Gatus, Barrie ^c   Mclachlan, Andrew J ^c   Salonikas, Chris ^a   Naidoo, Daya ^a   Goldberg, Ivan ^a   Lam, Chi Man ^a  

^a Department of Ophthalmology ^*  (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADOLESCENT; ADULT; AGED; AQUEOUS HUMOR; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG RESEARCH; EYE; FEMALE; HUMAN; MALE; MINIMUM INHIBITORY CONCENTRATION; PRIORITY JOURNAL; VITREOUS BODY;

ADULT; AGED; ANTI-INFECTIVE AGENTS; CIPROFLOXACIN; EYE; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 0034120557     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.6.1674-1679.2000     Document Type: Article

References (31)

1. Aarons, L. 1991. Population pharmacokinetics: theory and practice. Br. J. Clin. Pharmacol. 32:669-670.
2. Aarons, L. 1993. Sparse data analysis. Eur. J. Drug Metab. Pharmacokinet. 18:97-100.
3. Alfaro, D. V., S. J. Hudson, M. M. Rafanan, S. T. Moss, and S.-D. P. Levy. 1996. The effect of trauma on the ocular penetration of intravenous ciprofloxacin. Am. J. Ophthalmol. 122:678-683.
4. Behrens-Baumann, W., and J. Martell. 1987. Ciprofloxacin concentrations in human aqueous following intravenous administration. Chemotherapy (Basel) 33:328-330.
5. Bennett, J. E., and J. C. Wakefield. 1996. A comparison of a Bayesian population method with two methods as implemented in commercially available software. J. Pharmacokinet. Biopharm. 24:403-432.
6. Coburn, W. A. 1981. Simultaneous pharmacokinetic and pharmacodynamic modelling. J. Pharmacokinet. Biopharm. 9:367-388.
7. Donnenfeld, E. D., A. Schrier, T. Perry, T. Aulicino, M. E. Gombert, and R. Snyder. 1994. Penetration of topically applied ciprofloxacin, norfloxacin and ofloxacin into the aqueous. Ophthalmology 101:902-905.
8. Drusano, G. L., W. Liu, R. Perkins, A. Madhu, C. Madhu, M. Mayers, and M. H. Miller. 1995. Determination of robust ocular pharmacokinetic parameters in serum and vitreous of albino rabbits following systemic administration of ciprofloxacin from sparse data sets by using IT2, a population pharmacokinetic modeling program. Antimicrob. Agents Chemother. 39: 1683-1687.
9. Drusano, G. L., K. I. Plaisance, A. Forrest, and H. C. Standiford. 1986. Dose ranging study and constant infusion evaluation of ciprofloxacin. Antimicrob. Agents Chemother. 30:440-443.
10. El Baba, F. Z., M. D. Trousdale, J. Gauderman, D. G. Wagner, and P. E. Liggett. 1992. Intravitreal penetration of oral ciprofloxacin in humans. Ophthalmology 99:483-486.
11. Fern, A. I., G. Sweeney, M. Doig, and G. Lindsay. 1986. Penetration of ciprofloxacin into aqueous. Trans. Ophthalmol. Soc. 105:650-652.
12. Gomeni, R., G. Pineau, and F. Ment. 1994. Population kinetics and conditional assessment of the optimal dosage regimen using P-PHARM software package. Anticancer Res. 14:2321-2326.
13. Gonzalez, M. A., A. H. Moranchel, S. Duran, A. Pichardo, J. L. Magana, B. Painter, and G. L. Drusano. 1985. Multiple-dose ciprofloxacin dose ranging and kinetics. Clin. Pharmacol. Ther. 37:633-637.
14. Gonzalez, M. A., A. H. Moranchel, S. Duran, A. Pichardo, J. L. Magana, B. Painter, A. Forrest, and G. L. Drusano. 1985. Multiple dose pharmacokinetics of ciprofloxacin administered to normal volunteers. Antimicrob. Agents Chemother. 28:235-239.
15. Graham, G. 1987. Kinetics of non-steroidal anti-inflammatory drugs in synovial fluid. Agents Actions 24(Suppl.):66-75.
16. Gumbel, H., O. E. Schnaudigel, W. Heider, and P. M. Shah. 1989. Penetration von ciprofloxacin in das Kammerwasser nach parenteraler Anwendung. Fac Frotschr. Antimikroh. Antiepolast. Chemother. 8:61-64.
17. Keren, G., A. Alhalel, E. Bartov, R. Kitzes-Cohen, E. Rubinstein, S. Segev, and G. Treister. 1991. The intravitreal penetration of orally administered ciprofloxacin in humans. Investig. Ophthalmol. Vis. Sci. 32:2388-2392.
18. Kowalski, H. P., L. M. Karenchak, and A. W. Eller. 1993. The role of ciprofloxacin in endophthalmitis therapy. Am. J. Ophthalmol. 116:695-699.
19. Leeming, J. P., J. P. Diamond, R. Trigg, L. White, H. B. Hoh, and D. L. Easty. 1994. Ocular penetration of topical ciprofloxacin and norfloxacin drops and their effect upon eyelid flora. Br. J. Ophthalmol. 78:546-548.
20. Lesk, M. R., H. Ammann, G. Marcil, B. Vinet, L. Lamer, and M. Sebag. 1993. The penetration of oral ciprofloxacin into the aqueous, vitreous and subretinal fluid of humans. Am. J. Ophthalmol. 115:623-628.
21. Luthy, R., B. Joos, and F. Gassmann. 1986. The 1st International Ciprofloxacin Workshop, p. 192-196. Excerpta Medica, Amsterdam, The Netherlands.
22. Madu, A. A., M. Mayers, R. Perkins, W. Liu, G. L. Drusano, R. Aswani, C. N. Madu, and M. H. Miller. 1996. Aqueous and vitreous penetration of ciprofloxacin following different modes of systemic administration. Exp. Eye Res. 63:129-136.
23. McLachlan, A. J., and S. E. Tett. 1996. Pharmacokinetics of fluconazole in people with HIV infection: a population analysis. Br. J. Clin. Pharmacol. 41:291-298.
24. Mounier, M., J. P. Adenis, and F. Denis. 1988. Intraocular penetration of ciprofloxacin after infusion and oral administration. Pathol. Biol. 36:724-727.
25. Nix, D. E., J. M. DeVito, and J. J. Schentag. 1985. Liquid Chromatographic determination of ciprofloxacin in serum. Clin. Chem. 31:684-686.
26. Noe, D. A., and K. M. Kumor. 1983. Drug kinetics in low flux (small) anatomic compartments. J. Pharm. Sci. 72:718-719.
27. Phillips, I., A. King, and K. Shannon. 1988. In vitro properties of the quinolones, p. 83-117. In V. T. Andriole (ed.), The quinolones. Academic Press, London, United Kingdom.
28. Sweeney, G., A. I. Fern, G. Lindsay, and M. W. Doig. 1990. Penetration of ciprofloxacin into the uninflamed human eye after oral administration. J. Antimicrob. Chemother. 26:99-105.
29. Upton, R. N. 1994. An analysis of errors arising from the direct use of mass balance principles to describe regional drug uptake and elution. J. Pharmacokinet. Biopharm. 22:309-321.
30. Vance-Bryan, K., D. R. P. Guay, and J. C. Rotschafer. 1990. Clinical pharmacokinetics of ciprofloxacin. Clin. Pharmacokinet. 19:434-461.
31. Whiting, B., A. W. Kelman, and J. Grevel. 1985. Population pharmacokinetics: theory and clinical application. Clin. Pharmacokinet. 11:387-401.