Chitosan application to X-ray irradiated wound in dogs

Journal of Plastic, Reconstructive and Aesthetic Surgery

Volumn 60, Issue 3, 2007, Pages 304-310

  Ueno, H ^a,b   Ohya, T ^a   Ito, H ^a   Kobayashi, Y ^a   Yamada, K ^a   Sato, M ^a  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Chitosan; Dog; Growth factor; Wound healing; X ray radiation

Indexed keywords

CHITOPACK C; CHITOSAN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR A; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; VASCULOTROPIN;

ACCELERATION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY PROLIFERATION; CELL DAMAGE; CONTROLLED STUDY; DOG; ENDOTHELIUM CELL; FIBROBLAST; GRANULATION TISSUE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION INJURY; WOUND DRESSING; WOUND HEALING; WOUND HEALING IMPAIRMENT; X IRRADIATION;

ANIMALS; CHITOSAN; DOGS; GRANULATION TISSUE; GROWTH SUBSTANCES; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; PLATELET-DERIVED GROWTH FACTOR; RADIATION INJURIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SKIN; TRANSFORMING GROWTH FACTOR BETA1; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 33846781232     PISSN: 17486815     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bjps.2006.06.024     Document Type: Article

References (30)

1. Clark R.A. Cutaneous tissue repair: basic biologic considerations. J Am Acad Dermatol 13 (1985) 701-725
2. Nathan C., and Sporn M. Cytokines in context. J Cell Biol 113 (1991) 981-986
3. Bernstein E.F., Harisiadis L., Salomon G.D., et al. Healing impairment of open wounds by skin irradiation. J Dermatol Surg Oncol 20 (1994) 757-760
4. Peat B.G., Bell R.S., Davis A., et al. Wound-healing complications after soft-tissue sarcoma surgery. Plast Reconstr Surg 93 (1994) 980-987
5. Wang Q., Dickson G.R., and Carr K.E. The effect of graft-bed irradiation on the healing of rat skin grafts. J Invest Dermatol 106 (1996) 1053-1057
6. Schultze-Mosgau S., Wehrhan F., Grabenbauer G., et al. Transforming growth factor beta1 and beta2 (TGFbeta2/TGFbeta2) profile changes in previously irradiated free flap beds. Head Neck 24 (2002) 33-41
7. Schultze-Mosgau S., Grabenbauer G.G., Radespiel-Troger M., et al. Vascularization in the transition area between free grafted soft tissues and pre-irradiated graft bed tissues following preoperative radiotherapy in the head and neck region. Head Neck 24 (2002) 42-51
8. Langberg C.W., Hauer-Jensen M., Sung C.C., et al. Expression of fibrogenic cytokines in rat small intestine after fractionated irradiation. Radiother Oncol 32 (1994) 29-36
9. Herskind C., Bamberg M., and Rodemann H.P. The role of cytokines in the development of normal-tissue reactions after radiotherapy. Strahlenther Onkol 174 (1998) 12-15
10. Wollina U., Liebold K., and Konrad H. Treatment of chronic radiation ulcers with recombinant platelet-derived growth factor and a hydrophilic copolymer membrane. J Eur Acad Dermatol Venereol 15 (2001) 455-457
11. Schultze-Mosgau S., Wehrhan F., Rodel F., et al. Improved free vascular graft survival in an irradiated surgical site following topical application of rVEGF. Int J Radiat Oncol Biol Phys 57 (2003) 803-812
12. Minami S., Okamoto Y., Hamada K., et al. Veterinary practice with chitin and chitosan. EXS 87 (1999) 265-277
13. Ueno H., Kadosawa T., Ochiai K., et al. Canine pyogranulomatous dermatitis caused by Nocardia-subspecies infection. J Jpn Vet Med Assoc 57 (2004) 113-115 [in Japanese with English abstract]
14. Ueno H., Yamada H., Tanaka I., et al. Accelerating effects of chitosan for healing at early phase of experimental open wound in dogs. Biomaterials 20 (1999) 1407-1414
15. Ueno H., Nakamura F., Murakami M., et al. Evaluation effects of chitosan for the extracellular matrix production by fibroblasts and the growth factors production by macrophages. Biomaterials 22 (2001) 2125-2130
16. Johnston D.E. Wound healing in skin. Vet Clin North Am Small Anim Pract 20 (1990) 1-25
17. Wang A.M., Doyle M.V., and Mark D.F. Quantitation of mRNA by the polymerase chain reaction. Proc Natl Acad Sci USA 86 (1989) 9717-9721
18. Grone A., Frisk A.L., and Baumgartner W. Cytokine mRNA expression in whole blood samples from dogs with natural canine distemper virus infection. Vet Immunol Immunopathol 65 (1998) 11-27
19. Matsunaga T., Warltier D.C., Weihrauch D.W., et al. Ischemia-induced coronary collateral growth is dependent on vascular endothelial growth factor and nitric oxide. Circulation 102 (2000) 3098-3103
20. Flamme I., Breier G., and Risau W. Vascular endothelial growth factor (VEGF) and VEGF receptor 2 (flk-1) are expressed during vasculogenesis and vascular differentiation in the quail embryo. Dev Biol 169 (1995) 699-712
21. Senger D.R., Claffey K.P., Benes J.E., et al. Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins. Proc Natl Acad Sci USA 94 (1997) 13612-13617
22. Hippenstiel S., Krull M., Ikemann A., et al. VEGF induces hyperpermeability by a direct action on endothelial cells. Am J Physiol 274 (1998) L678-L684
23. Howdieshell T.R., Callaway D., Webb W.L., et al. Antibody neutralization of vascular endothelial growth factor inhibits wound granulation tissue formation. J Surg Res 96 (2001) 173-182
24. Frank S., Hubner G., Breier G., et al. Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing. J Biol Chem 270 (1995) 12607-12613
25. Minami S., Suzuki H., Okamoto Y., et al. Chitin and chitosan activate complement via the alternative pathway. Carbohydr Polym 36 (1998) 151-155
26. Wang J., Zheng H., Ou X., et al. Deficiency of microvascular thrombomodulin and up-regulation of protease-activated receptor-1 in irradiated rat intestine: possible link between endothelial dysfunction and chronic radiation fibrosis. Am J Pathol 160 (2002) 2063-2072
27. Senger D.R., Ledbetter S.R., Claffey K.P., et al. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin. Am J Pathol 149 (1996) 293-305
28. Ueno H., Murakami M., Okumura M., et al. Chitosan accelerates the production of osteopontin from polymorphonuclear leukocytes. Biomaterials 22 (2001) 1667-1673
29. Denhart B.C., Guidi A.J., Tognazzi K., et al. Vascular permeability factor/vascular endothelial growth factor and its receptors in oral and laryngeal squamous cell carcinoma and dysplasia. Lab Invest 77 (1997) 659-664
30. Senger D.R., Perruzzi C.A., Streit M., et al. The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. Am J Pathol 160 (2002) 195-204