Is metformin safe in patients with mild renal insufficiency? [1]

Diabetes Care

Volumn 30, Issue 2, 2007, Pages 444-

  Kazory, Amir ^a   Walsh, Katherine ^a,b   Harman, Eloise ^a   Talor, Zvi ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPTOPRIL; CREATININE; GLIBENCLAMIDE; HYDROCHLOROTHIAZIDE; METFORMIN; NIFEDIPINE;

ADULT; CASE REPORT; CLINICAL EXAMINATION; CLINICAL FEATURE; CONGESTIVE HEART FAILURE; DRUG SAFETY; EXTUBATION; HUMAN; HYPOTENSION; KIDNEY FAILURE; LABORATORY TEST; LACTIC ACIDOSIS; LETTER; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; RESPIRATORY DISTRESS; RISK FACTOR; SYMPTOMATOLOGY;

DIABETIC NEPHROPATHIES; HUMANS; HYPOGLYCEMIC AGENTS; HYPOTENSION; LUNG DISEASES; MALE; METFORMIN; MIDDLE AGED;

EID: 33846709906     PISSN: 01495992     EISSN: 01495992     Source Type: Journal    
DOI: 10.2337/dc06-2155     Document Type: Letter

References (5)

1. Misbin RI, Green L, Stadel BV, Gueriquian JL, Gubbi A, Fleming GA: Lactic acidosis in patients with diabetes treated with metformin. N Engl J Med 338:265-266, 1998
2. Misbin RI: The phantom of lactic acidosis due to metformin in patients with diabetes. Diabetes Care 27:1791-1793, 2004
3. Salpeter S, Greyber G, Pasternak G, Salpeter E: Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus. Cochrane Database Sys Rev no. CD002967, 2006
4. Luft FC: Lactic acidosis update for critical care clinicians. J Am Soc Nephrol 12:S15-S19, 2001
5. Holstein A, Stumvoll M: Contraindications can damage your health: is metformin a case in point? Diabetologia 48:2454-2459, 2005