Quantifying the normal range of myocardial blood flow with 13N-ammonia PET and tracer kinetic modeling

IEEE Nuclear Science Symposium Conference Record

Volumn 3, Issue , 2005, Pages 1686-1690

  Renaud, Jennifer M ^b   Lortie, Mireille ^b   Wassenaar, Richard W ^a,b   Dasilva, Jean ^b   Beanlands, Robert S ^b   DeKemp, Robert A ^a,b  

^a IEEE   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD FLOW; CORONARY ARTERY DISEASE (CAD); RETENTION RATE; TRACER KINETIC MODELING;

AMMONIA; BLOOD; CARDIOLOGY; COMPUTER SIMULATION; DATABASE SYSTEMS; DIAGNOSTIC RADIOGRAPHY; DISEASES; PATIENT MONITORING; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS;

HEMODYNAMICS;

EID: 33846645278     PISSN: 10957863     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/NSSMIC.2005.1596644     Document Type: Conference Paper

References (14)

1. Y. Choi et al., "A simplified method for quantification of myocardial blood flow using nitrogen-13-ammonia and dynamic PET", J. Nucl. Med., vol. 34, no. 3, pp. 488-497, Mar. 1993.
2. O. Muzik et al., "Assessment of diagnostic performance of quantitative flow measurements in normal subjects and patients with angiographically documented coronary artery disease by means of nitrogen-13 ammonia and positron emission tomography", J. Am. Coll. Cardiol., vol. 3, no. 3, pp. 534-540, Mar. 1998.
3. H. R. Schelbert et al., "Noninvasive assessment of coronary stenoses by myocardial imaging during pharmacologic coronary vasodilation. VI. Detection of coronary artery disease in human beings with intravenous N-13 ammonia and positron computed tomography", Am. J. Cardiol., vol. 49, no. 5, pp. 1197-1207, Apr. 1982.
4. R. Parkash et al., "Potential utility of rubidium 82 PET quantification in patients with 3-vessel coronary artery disease", J. Nucl. Cardiol., vol. 11, no. 4, pp. 440-449, Jul.-Aug. 2004.
5. G. A. Diamond, J. S. Forrester, "Analysis of probability as an aid in the clinical diagnosis of coronary-artery disease". N. Engl. J. Med., vol. 300, no. 24, pp. 1350-1358, Jun. 1979.
6. R. A. deKemp, C. Nahmias, "Automated determination of the left ventricular long axis in cardiac positron emission tomography", Physiol. Meas., vol. 17, no. 2, pp. 95-108, May 1996.
7. C. Laubenbacher et al., "An automated analysis program for the evaluation of cardiac PET studies: initial results in the detection and localization of coronary artery disease using nitrogen- 13-ammonia", J. Nucl. Med., vol. 34, no. 6, pp. 968-978, Jun. 1993.
8. G. D. Hutchins, M. Schwaiger, K. C. Rosenspire, J. Krivokapich, H. Schelbert, D. E. Kuhl, "Noninvasive quantification of regional blood flow in the human heart using N-13 ammonia and dynamic positron emission tomographic imaging", J. Am. Coll. Cardiol., vol. 15, pp. 1032-1042, Apr. 1990.
9. H. K. Thompson, F. Starmer, R. E. Whalen, H. D. McIntosh, "Indicator transit time considered as gamma variate", Circ. Res., vol. 14, pp. 502-515, June 1964.
10. R. Wassenaar, R. A. deKemp, "Extravascular Density Model for PET Partial Volume Correction", 2005 IEEE NSS/MIC Conference Record (in press).
11. H. Gewirtz, A. J. Fischman, S. Abraham, M. Gilson, H. W. Strauss, N. M. Alpert, "Positron emission tomographic measurements of absolute regional myocardial blood flow permits identification of nonviable myocardium in patients with chronic myocardial infarction", J. Am. Coll. Cardiol., vol. 23, no. 4, pp. 851-859, Mar. 1994.
12. H. R. Schelbert et al., "N-13 ammonia as an indicator of myocardial blood flow", Circulation, vol. 63, no. 6, pp. 1259-1272, June 1981.
13. C. A. Nienaber et al., "A quantitative index of regional blood flow in canine myocardium derived noninvasively with N-13 ammonia and dynamic positron emission tomography", J. Am. Coll. Cardiol., vol. 17, no. 1, pp. 260-269, Jan. 1991.
14. C. R. Bellina et al., "Simultaneous in vitro and in vivo validation of nitrogen-13-ammonia for the assessment of regional myocardial blood flow", J. Nucl. Med., vol. 31, no. 8, pp. 1335-1343, Aug. 1990.