Finding ligands for G protein-coupled receptors based on the protein-compound affinity matrix

Journal of Molecular Graphics and Modelling

Volumn 25, Issue 5, 2007, Pages 633-643

  Fukunishi, Yoshifumi ^a   Kubota, Satoru ^b   Nakamura, Haruki ^a,c  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b Japan Biological Information Research Center   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Database enrichment; GPCR; Principal component analysis; Protein compound interaction matrix; Receptor ligand docking

Indexed keywords

AMINES; COMPUTER SIMULATION; CONFORMATIONS; MOLECULAR STRUCTURE; PRINCIPAL COMPONENT ANALYSIS; SOLUBILITY;

DOPAMINE; HISTAMINE; LIGANDS; PROTEIN COMPOUND INTERACTION MATRIX; RECEPTOR LIGAND DOCKING; SEROTONIN;

PROTEINS;

ANTIHISTAMINIC AGENT; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; DOPAMINE RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; HISTAMINE AGONIST; HISTAMINE RECEPTOR; LIGAND; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ARTICLE; CALCULATION; LIGAND BINDING; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; RECEPTOR BINDING; SIMULATION;

BINDING SITES; COMPUTER SIMULATION; DRUG EVALUATION, PRECLINICAL; LIGANDS; MODELS, MOLECULAR; PRINCIPAL COMPONENT ANALYSIS; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED;

EID: 33846637709     PISSN: 10933263     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmgm.2006.05.001     Document Type: Article

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