메뉴 건너뛰기




Volumn 16, Issue 2, 2007, Pages 233-241

Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

EID: 33846637323     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl473     Document Type: Article
Times cited : (89)

References (45)
  • 1
    • 85082596263 scopus 로고    scopus 로고
    • Urban World, Global City. Routledge, UK
    • Clark, D. (2004) Urban World, Global City. Routledge, UK.
    • (2004)
    • Clark, D.1
  • 2
    • 17644380640 scopus 로고    scopus 로고
    • Increased level of linkage disequilibrium in rural compared to urban communities: A factor to consider in association study design
    • Vitart, V., Carothers, A.D., Suffolk, R., Hayward, C., Teague, P., Hastie, N.D., Campbell, H. and Wright, A.F. (2005) Increased level of linkage disequilibrium in rural compared to urban communities: A factor to consider in association study design. Am. J. Hum. Genet., 76, 763-772.
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 763-772
    • Vitart, V.1    Carothers, A.D.2    Suffolk, R.3    Hayward, C.4    Teague, P.5    Hastie, N.D.6    Campbell, H.7    Wright, A.F.8
  • 3
    • 13944284207 scopus 로고    scopus 로고
    • The beauty of admixture
    • Darvasi, A. and Shifman, S. (2005) The beauty of admixture. Nat. Genet., 37, 118-119.
    • (2005) Nat. Genet. , vol.37 , pp. 118-119
    • Darvasi, A.1    Shifman, S.2
  • 4
    • 11244279011 scopus 로고    scopus 로고
    • An Icelandic example of the impact of population structure on association studies
    • Helgason, A., Ingvadottir, B., Hrafnkelsson, B., Gulcher, J. and Stefansson, K. (2005) An Icelandic example of the impact of population structure on association studies. Nat. Genet., 37, 90-95.
    • (2005) Nat. Genet. , vol.37 , pp. 90-95
    • Helgason, A.1    Ingvadottir, B.2    Hrafnkelsson, B.3    Gulcher, J.4    Stefansson, K.5
  • 5
    • 0024312266 scopus 로고
    • Age-dependent changes in morphometric and biochemical traits
    • Kobylianski, E. and Livshits, G. (1989) Age-dependent changes in morphometric and biochemical traits. Ann. Hum. Biol., 16, 237-247.
    • (1989) Ann. Hum. Biol. , vol.16 , pp. 237-247
    • Kobylianski, E.1    Livshits, G.2
  • 6
    • 0029994356 scopus 로고    scopus 로고
    • Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence
    • Charlesworth, B. and Hughes, K.A. (1996) Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence. Proc. Natl Acad. Sci. USA, 93, 6140-6145.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 6140-6145
    • Charlesworth, B.1    Hughes, K.A.2
  • 8
    • 0034753277 scopus 로고    scopus 로고
    • Familial studies of medical and anthropometric variables in a human isolate
    • Ober, C., Abney, M. and McPeek, M.S. (2001) Familial studies of medical and anthropometric variables in a human isolate. Am. J. Hum. Genet., 69, 1068-1079.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1068-1079
    • Ober, C.1    Abney, M.2    McPeek, M.S.3
  • 9
    • 0035023261 scopus 로고    scopus 로고
    • Broad and narrow heritabilities of quantitative traits in a founder population
    • Abney, M., McPeek, M.S. and Ober, C. (2001) Broad and narrow heritabilities of quantitative traits in a founder population. Am. J. Hum. Genet., 68, 1302-1307.
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 1302-1307
    • Abney, M.1    McPeek, M.S.2    Ober, C.3
  • 10
    • 0003731907 scopus 로고    scopus 로고
    • World Health Report 2002: Reducing risks, promoting healthy life
    • World Health Organisation WHO, Geneva
    • World Health Organisation (2002) World Health Report 2002: Reducing risks, promoting healthy life. WHO, Geneva.
    • (2002)
  • 16
    • 84872239752 scopus 로고    scopus 로고
    • Age-stratified heritability estimation in the Framingham Heart Study families
    • Framingham Heart Study
    • Brown, W.M., Beck, S.R., Lange, E.M., Dvid, C.C., Kay, C.M., Langefeld, C.D. and Rich, S.S. (2003) Framingham Heart Study. Age-stratified heritability estimation in the Framingham Heart Study families. BMC Genet., 4(Suppl. 1), S32.
    • (2003) BMC Genet. , vol.4 , Issue.SUPPL. 1
    • Brown, W.M.1    Beck, S.R.2    Lange, E.M.3    Dvid, C.C.4    Kay, C.M.5    Langefeld, C.D.6    Rich, S.S.7
  • 17
    • 0025776299 scopus 로고
    • Reproductive behaviour and health in consanguineous marriages
    • Bittles, A.H., Mason, W.M., Greene, J. and Rao, N.A. (1991) Reproductive behaviour and health in consanguineous marriages. Science, 252, 789-794.
    • (1991) Science , vol.252 , pp. 789-794
    • Bittles, A.H.1    Mason, W.M.2    Greene, J.3    Rao, N.A.4
  • 18
    • 0028025362 scopus 로고
    • The costs of human inbreeding and their implications for variations at the DNA level
    • Bittles, A.H. and Neel, J.V. (1994) The costs of human inbreeding and their implications for variations at the DNA level. Nat. Genet., 8, 117-121.
    • (1994) Nat. Genet. , vol.8 , pp. 117-121
    • Bittles, A.H.1    Neel, J.V.2
  • 19
    • 12244313454 scopus 로고    scopus 로고
    • Five reasons why inbreeding may have considerable effect on post-reproductive human health
    • Rudan, I. and Campbell, H. (2004) Five reasons why inbreeding may have considerable effect on post-reproductive human health. Coll. Antropol., 28, 943-950.
    • (2004) Coll. Antropol. , vol.28 , pp. 943-950
    • Rudan, I.1    Campbell, H.2
  • 20
    • 0028163708 scopus 로고
    • An experimental study of inbreeding depression in a natural habitat
    • Jimenez, J.A., Hughes, K.A., Alaks, G., Graham, L. and Lacy, R.C. (1994) An experimental study of inbreeding depression in a natural habitat. Science, 266, 271-273.
    • (1994) Science , vol.266 , pp. 271-273
    • Jimenez, J.A.1    Hughes, K.A.2    Alaks, G.3    Graham, L.4    Lacy, R.C.5
  • 21
    • 0037422038 scopus 로고    scopus 로고
    • Inbreeding: Disease susceptibility in Californian sea lions
    • Acevedo-Whitehouse, K., Gulland, F., Greig, D. and Amos, W. (2003) Inbreeding: Disease susceptibility in Californian sea lions. Nature, 422, 35.
    • (2003) Nature , vol.422 , pp. 35
    • Acevedo-Whitehouse, K.1    Gulland, F.2    Greig, D.3    Amos, W.4
  • 22
    • 0028116098 scopus 로고
    • Genetic and environmental effects on coronary heart disease risk factors in northern Norway. The cardiovascular disease study in Finnmark
    • Brenn, T. (1994) Genetic and environmental effects on coronary heart disease risk factors in northern Norway. The cardiovascular disease study in Finnmark. Ann. Hum. Genet., 58, 369-379.
    • (1994) Ann. Hum. Genet. , vol.58 , pp. 369-379
    • Brenn, T.1
  • 23
    • 0033942762 scopus 로고    scopus 로고
    • Estimation of variance components of quantitative traits in inbred populations
    • Abney, M., McPeek, M.S. and Ober, C. (2000) Estimation of variance components of quantitative traits in inbred populations. Am. J. Hum. Genet., 66, 629-650.
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 629-650
    • Abney, M.1    McPeek, M.S.2    Ober, C.3
  • 25
    • 13144306071 scopus 로고    scopus 로고
    • Genome-wide association studies for common diseases and complex traits
    • Hirschhorn, J.N. and Daly, M.J. (2005) Genome-wide association studies for common diseases and complex traits. Nat. Rev. Genet., 6, 95-108.
    • (2005) Nat. Rev. Genet. , vol.6 , pp. 95-108
    • Hirschhorn, J.N.1    Daly, M.J.2
  • 26
    • 0015754302 scopus 로고
    • Familial studies of medical and anthropometric variables in a human isolate
    • Martin, A.O., Kurczynskim, T.W. and Steinberg, A.G. (1973) Familial studies of medical and anthropometric variables in a human isolate. Am. J. Hum. Genet., 25, 581-593.
    • (1973) Am. J. Hum. Genet. , vol.25 , pp. 581-593
    • Martin, A.O.1    Kurczynskim, T.W.2    Steinberg, A.G.3
  • 27
    • 0014596824 scopus 로고
    • Inbreeding effects on metrical traits in Northeastern Brasil
    • Krieger, H. (1986) Inbreeding effects on metrical traits in Northeastern Brasil. Am. J. Hum. Genet., 21, 537-546.
    • (1986) Am. J. Hum. Genet. , vol.21 , pp. 537-546
    • Krieger, H.1
  • 28
    • 31744449136 scopus 로고    scopus 로고
    • The sex-specific genetic architecture of quantitative traits in humans
    • Weiss, L.A., Pan, L., Abney, M. and Ober, C. (2005) The sex-specific genetic architecture of quantitative traits in humans. Nat. Genet., 38, 218-222.
    • (2005) Nat. Genet. , vol.38 , pp. 218-222
    • Weiss, L.A.1    Pan, L.2    Abney, M.3    Ober, C.4
  • 29
    • 0037504137 scopus 로고    scopus 로고
    • Sex-dependent gene expression and evolution of the Drosophila transcriptome
    • Ranz, J.M., Castillo-Davis, D.I., Meiklejohn, C.D. and Hartl, D.L. (2003) Sex-dependent gene expression and evolution of the Drosophila transcriptome. Science, 300, 1742-1745.
    • (2003) Science , vol.300 , pp. 1742-1745
    • Ranz, J.M.1    Castillo-Davis, D.I.2    Meiklejohn, C.D.3    Hartl, D.L.4
  • 30
    • 0035230102 scopus 로고    scopus 로고
    • Quantitative trait loci in Drosophila
    • Mackay, T.F.C. (2001) Quantitative trait loci in Drosophila. Nat. Rev. Genet., 2, 11-20.
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 11-20
    • Mackay, T.F.C.1
  • 31
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • Lifton, R.P., Gharavi, A.G. and Geller, D.S. (2001) Molecular mechanisms of human hypertension. Cell, 104, 545-556.
    • (2001) Cell , vol.104 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 32
    • 0036568655 scopus 로고    scopus 로고
    • Inbreeding effects in wild populations
    • Keller, L.F. and Waller, D.M. (2002) Inbreeding effects in wild populations. Trends Ecol. Evol., 17, 230-242.
    • (2002) Trends Ecol. Evol. , vol.17 , pp. 230-242
    • Keller, L.F.1    Waller, D.M.2
  • 33
    • 18144407284 scopus 로고    scopus 로고
    • Inbreeding-lessons from animal breeding, evolutionary biology and conservation genetics
    • Kristensen, T.N. and Sorensen, A.C. (2005) Inbreeding-lessons from animal breeding, evolutionary biology and conservation genetics. Animal Sci., 80, 121-133.
    • (2005) Animal Sci. , vol.80 , pp. 121-133
    • Kristensen, T.N.1    Sorensen, A.C.2
  • 34
    • 28044462930 scopus 로고    scopus 로고
    • Genetic diversity and reproductive success in mandrills (Mandrillus sphinx)
    • Charpentier, M., Setchell, J.M. and Prugnolle, F. (2005) Genetic diversity and reproductive success in mandrills (Mandrillus sphinx). Proc. Natl Acad. Sci. USA, 102, 16723-16728.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 16723-16728
    • Charpentier, M.1    Setchell, J.M.2    Prugnolle, F.3
  • 35
    • 0037819442 scopus 로고    scopus 로고
    • Captivity masks inbreeding effects on male mating success in butterflies
    • Joron, M. and Brakefield, P.M. (2003) Captivity masks inbreeding effects on male mating success in butterflies. Nature, 424, 191-194.
    • (2003) Nature , vol.424 , pp. 191-194
    • Joron, M.1    Brakefield, P.M.2
  • 36
    • 8644278755 scopus 로고    scopus 로고
    • Inbreeding effects on metrical phenotypes among North Indian Children
    • Badaruddoza (2004) Inbreeding effects on metrical phenotypes among North Indian Children. Coll. Antropol., 28(Suppl. 2), 311-319.
    • (2004) Coll. Antropol. , vol.28 , Issue.SUPPL. 2 , pp. 311-319
    • Badaruddoza1
  • 37
    • 0346723044 scopus 로고    scopus 로고
    • The secular rise in IQ: Giving heterosis a closer look
    • Mingroni, M.A. (2004) The secular rise in IQ: Giving heterosis a closer look. Intelligence, 32, 65-83.
    • (2004) Intelligence , vol.32 , pp. 65-83
    • Mingroni, M.A.1
  • 41
    • 33747825087 scopus 로고    scopus 로고
    • Mendelian diseases and conditions in Croatian island populations: Historic records and new insights
    • Saftic, V., Rudan, D. and Zgaga, L. (2006) Mendelian diseases and conditions in Croatian island populations: Historic records and new insights. Croat. Med. J., 47, 543-552.
    • (2006) Croat. Med. J. , vol.47 , pp. 543-552
    • Saftic, V.1    Rudan, D.2    Zgaga, L.3
  • 42
    • 33747826611 scopus 로고    scopus 로고
    • Strategy for mapping quantitative trait loci (QTL) by using human metapopulations
    • Rudan, I., Biloglav, Z., Carothers, A.D., Wright, A.F. and Campbell, H. (2006) Strategy for mapping quantitative trait loci (QTL) by using human metapopulations. Croat. Med. J., 47, 532-542.
    • (2006) Croat. Med. J. , vol.47 , pp. 532-542
    • Rudan, I.1    Biloglav, Z.2    Carothers, A.D.3    Wright, A.F.4    Campbell, H.5
  • 45
    • 26444496137 scopus 로고    scopus 로고
    • Adjusting for treatment effects in studies of quantitative traits: Antihypertensive therapy and systolic blood pressure
    • Tobin, M.D., Sheehan, N.A., Scurrah, K.J. and Burton, P.R. (2005) Adjusting for treatment effects in studies of quantitative traits: antihypertensive therapy and systolic blood pressure. Stat. Med, 24, 2911-2935.
    • (2005) Stat. Med , vol.24 , pp. 2911-2935
    • Tobin, M.D.1    Sheehan, N.A.2    Scurrah, K.J.3    Burton, P.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.