Two related thrombin-like enzymes present in Bothrops atrox venom

Brazilian Journal of Medical and Biological Research

Volumn 33, Issue 11, 2000, Pages 1293-1300

  Petretski, J H ^a   Kanashiro, M ^a   Silva, C P ^a   Alves, E W ^a   Kipnis, T L ^a  

^a UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE DARCY RIBEIRO   (Brazil)

Author keywords

Blood coagulation system; Bothrops atrox; Enzymes; Thrombin like enzymes; Venoms

Indexed keywords

BOTHROPS ATROX; BOTHROPS JARARACA; BOTHROPS LEUCURUS; BOTHROPS MOOJENI;

FIBRINOGEN; ISOENZYME; SNAKE VENOM; THROMBIN;

ANIMAL; ARTICLE; BLOOD CLOTTING; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; ISOLATION AND PURIFICATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; SERODIAGNOSIS; SNAKE; WESTERN BLOTTING;

ANIMALS; BLOOD COAGULATION; BLOTTING, WESTERN; BOTHROPS; CROTALID VENOMS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBRINOGEN; ISOENZYMES; PRECIPITIN TESTS; THROMBIN;

EID: 0034326394     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2000001100005     Document Type: Article

References (26)

1. Stocker K & Meier J (1988). Thrombin-like snake venom enzymes. In: Pirkle H & Markland FS (Editors), Hemostasis and Animal Venoms. Marcel Dekker, New York.
2. Pirkle H & Theodor I (1991). Thrombin-like enzymes from snake venoms. In: Tu AT (Editor), Handbook of Natural Toxins. Vol. 5. Reptile Venoms and Toxins. Pergamon Press, London.
3. Zhang Y, Gao R, Lee WH, Zhu SW, Xiong YL & Wang WY (1998). Characterization of a fibrinogen-clotting enzyme from Trimeresurus stejnegeri venom and comparative study with other venom proteases. Toxicon, 36: 131-142.
4. Kisiel W (1979). Molecular properties of the factor V-activating enzyme from Russell's viper venom. Journal of Biological Chemistry, 254: 12230-12234.
5. Tokunaga F, Nagasawa K, Tamura S, Miyata T, Iwanaga S & Kisiel W (1988). The factor V-activating enzyme (RVV-V) from Russell's viper venom. Identification of isoproteins RVV-Va, -Vb and -Vr and their complete amino acid sequence Journal of Biological Chemistry, 263: 17471-17481.
6. Kisiel W, Kondo S, Smith KJ, McMullen BA & Smith LF (1987). Characterization of a protein C activator from Agkistrodon contortrix contortrix venom. Journal of Biological Chemistry, 262: 12607-12613.
7. McMullen BA, Fujikawa K & Kisiel W (1989). Primary structure of a protein C activator from Agkistrodon contortrix contortrix venom. Biochemistry, 28: 674-679.
8. Rocha e Silva M, Beraldo WT & Rosenfeld G (1949). Bradykinin, a hypotensive and smooth muscle stimulating factor released from plasma globulin by snake venoms and trypsin. American Journal of Physiology, 156: 261-271.
9. Markland FS, Kettner C, Schiffman S, Shaw E, Bajwa SS, Reddy KN, Kirakossian H, Patkos GB, Theodor I & Pirkle H (1982). Kallikrein-like activity of crotalase, a snake venom enzyme that clots fibrinogen. Proceedings of the National Academy of Sciences, USA, 79: 1688-1692.
10. Tambourgi DV, dos Santos MC, Furtado NFD, Freitas NCW, Dias da Silva W & Kipnis TL (1994). Pro-inflammatory activities in Elapidae snake venoms. British Journal of Pharmacology, 112: 723-727.
11. Cavinato RA, Remold H & Kipnis TL (1998). Purification and characterization of thrombin like activity from the venom of Bothrops atrox of different geographic regions. Toxicon, 36: 257-268.
12. Itoh N, Tanaka N, Mihashi S & Yamashima I (1987). Molecular cloning and sequence analysis of cDNA for batroxobin, a thrombin-like snake venom enzyme. Journal of Biological Chemistry, 262: 3132-3135.
13. Aguiar AS, Alves CR, Melgarejo A & Giovanni-De-Simone S (1995). Purification and partial characterization of a thrombin-like gyroxin enzyme from bushmaster (Lachesis muta rhombeata) venom. Toxicon, 34: 555-565.
14. Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W & Lipman DJ (1997). Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Research, 25: 3389-3402.
15. Köhler J & Milstein C (1975). Continuous culture of fused cells secreting antibody of predefined specificity. Nature, 256: 495-497.
16. Bozzo S & Retamal C (1991). Gel-perfect Geles unidimensionales, un nuevo método densitométrico para computadores personales. Archivos de Biologia y Medicina Experimentales, 24: 181-184.
17. Shieh TC, Kawahata SI, Kihara H, Ohno M & Iwanaga S (1988). Amino acid sequence of a coagulant enzyme, flavoxobin, from Trimeresurus flavoviridis venom. Journal of Biological Chemistry, 103: 596-605.
18. Rosenfeld G (1971). Symptomatology, pathology and treatment of snake bites in South America. In: Bucherl W, Buckley E & Deulofeu V (Editors), Venomous Animals and Their Venoms. Academic Press, New York.
19. Kamiguti AS & Cardoso JLC (1989). Haemostatic changes caused by the venoms of South American snakes. Toxicon, 27: 955-963.
20. Hatton MWC (1973). Studies on the coagulant enzyme from Agkistrodon rhodostoma venom. Isolation and some properties of the enzyme. Biochemical Journal, 131: 799-807.
21. Burkhart W, Smith GF, Su JL, Parikh I & LeVine H (1992). Amino acid sequence determination of ankrod, the thrombin-like α-fibrinogenase from the venom of Agkistrodon rhodostoma. FEBS Letters, 297: 297-301.
22. Shu YY, Moran JB & Green CR (1983). A thrombin-like enzyme from rattlesnake venom. Biochimica et Biophysica Acta, 748: 236-244.
23. Silveira AMV, Magalhães A, Diniz CR & De Oliveira EB (1996). Purification and properties of the thrombin-like enzyme from the venom of Lachesis muta muta. International Journal of Biochemistry, 21: 863-871.
24. Serrano SMT, Reinhardt M, Sampaio CAM & Fink E (1995). Purification, characterization and amino acid sequence of a serine proteinase, PA-BJ, with platelet-aggregating activity from the venom of Bothrops jararaca. Biochemistry, 34: 7186-7193.
25. Zaganelli GL, Zaganelli MGM, Magalhães A, Diniz CR & De Lima EM (1996). Purification and characterization of a fibrinogen-clotting enzyme from the venom of Jaracucu (Bothrops jararacussu). Toxicon, 34: 807-819.
26. Wuster W, Thorpe RS & Porto J (1996). Systematics of the Bothrops atrox complex (Reptilia:Serpentes:Viperidae) in Brazil: a multivariate analysis. Herpetologica, 52: 263-271.