Antitumor activity and antioxidant status of the methanol extract of Careya arborea bark against Dalton's lymphoma ascites-induced ascitic and solid tumor in mice

Journal of Pharmacological Sciences

Volumn 103, Issue 1, 2007, Pages 12-23

  Natesan, Senthilkumar ^a   Badami, Shrishailappa ^a   Dongre, Santoshkumar H ^a   Godavarthi, Ashok ^a  

^a JSS COLLEGE OF PHARMACY   (India)

Author keywords

Antioxidant; Antitumor; Careya arborea; Hepatoprotective; Solid tumor

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BUTYLATED HYDROXYANISOLE; CAREYA ARBOREA EXTRACT; FLUOROURACIL; METHANOL; PLANT EXTRACT; RUTOSIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASCITES; BARK; BARRINGTONIA; BLOOD ANALYSIS; CANCER TRANSPLANTATION; CAREYA ARBOREA; CELL COUNT; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; HEMATOCRIT; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER PARENCHYMA; LIVER PROTECTION; LUNG PARENCHYMA; LYMPHOMA; MEDICINAL PLANT; MOUSE; NONHUMAN; SOLID TUMOR; TISSUE REPAIR; TUMOR CELL; TUMOR VOLUME; WEIGHT REDUCTION;

EID: 33846566726     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.FP0060907     Document Type: Article

References (29)

1. Gordon MC, Newman DJ. Natural product drug discovery in the next millennium. Pharm Biol. 2001;39:8-17.
2. Premalatha B, Rajgopal G. Cancer - an ayurvedic perspective. Pharmacol Res. 2005;51:19-30.
3. Spiridon KE. Terrestrial plant-derived anticancer agents and plants used in anticancer research. Crit Rev Plant Sci. 2006;25:79-113.
4. Anonymous. The wealth of India - A dictionary of Indian raw materials and industrial products. New Delhi: CSIR; 1992. p. 273-276.
5. Kirtikar KR, Basu BD, editors. Indian medicinal plants. 2nd ed. Dehradun, India: Bishen Sing Mahendra Pal Sing; 1987. p. 1061-1063.
6. Rahman MT, Khan OF, Saha S, Alimuzzaman M. Anti-diarrhoeal activity of the bark extract of Careya arborea Roxb. Fitoterapia, 2003;74:116-118.
7. Sambath Kumar R, Sivakumar T, Sivakumar P, Nethaji R, Vijayabaskar M, Perumal P, et al. Hepatoprotective and in vivo antioxidant effects of Careya arborea against carbon tetrachloride induced liver damage in rats. Int J Mol Med Adv Sci. 2005;1:418-424.
8. Row LR, Sastry CSP. Chemical examination of Careya arborea Roxb. Ind J Chem. 1964;2:510-514.
9. Badami S, Prakash O, Dongre SH, Suresh B. In vitro antioxidant properties of Solanum pseudocapsicum leaf extracts. Ind J Pharmacol. 2005;37:251-252.
10. Sudheer Kumar M, Jagadish PC, Sridhar Reddy B, Kiran Babu S, Unnikrishnan MK. In vitro evoluation of antioxidant properties of Cocus nucifera L. extracts. Nahrung/Food. 2003;47:126-131.
11. Huong NTT, Matsumato K, Kasai R, Yamasaki K, Watanabe H. In vitro antioxidant activity of Vietnamese ginseng saponin and its components. Biol Pharm Bull. 1998;21:978-981.
12. Vijayan P, Vinod Kumar S, Dhanaraj SA, Mukherjee PK, Suresh B. In vitro cytotoxicity and antitumour properties of Hypericum mysorense and Hypericum patulum. Phytother Res. 2003;17:952-956.
13. Beers RF Jr, Sizer IW. A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem. 1952;195:133-140.
14. Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and simple assay for superoxide dismutase. J Biol Chem. 1972;247:3170-3175.
15. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissue by of thiobarbituric acid reaction. Anal Biochem. 1979;95:351-358.
16. Gupta M, Mazumder UK, Sambath kumar R, Sivakumar T, Vamsi MLM. Antitumor activity and antioxidant status of Caesalpinia bonducella against Ehrlich ascites carcinoma in Swiss albino mice. J Pharmacol Sci. 2004;94:177-184.
17. Kumar KBH, Kuttan R. Chemoprotective activity of an extract of Phyllanthus amarus against cyclophosphamide induced toxicity in mice. Phytomedicine. 2005;12:494-500.
18. Kim JB, Koo HN, Joeng HJ, Lyu YS, Park SG, Won JH, et al. Induction of apoptosis by Korean medicine Gagam-whanglyunhaedoktang through activation of caspase-3 in human leukemia cell line, HL-60 cells. J Pharmacol Sci. 2005;97:138-145.
19. Aoki K, Yamakuni T, Yoshida M, Ohizumi Y. Ephedrae herba decreases lipopolysaccharide-induced cyclooxgenase-2 protein expression and NF-κB-dependent transcription in C6 rat glioma cells. J Pharmacol Sci. 2005;98:327-330.
20. Saito SY, Maruyama Y, Kamiyama S, Nakahata N, Ohizumi Y. Ephedrae herba in Mao-Bushi-Saishin-To inhibits IgE-mediated histamine release and increases cAMP content in RBL-2H3 cells. J Pharmacol Sci. 2004;95:41-46.
21. 2+ ionophores, but not to tumor necrosis factor-α. J Pharmacol Sci. 2004;96:324-332.
22. Badami S, Reddy SAM, Kumar EP, Vijayan P, Suresh B. Antitumor activity of total alkaloid fraction of solanum pseudocapsicum leaves. Phytotherapy Res. 2003;17:1001-1004.
23. Bansal AK, Bansal M, Soni G, Bhanagar D. Protective role of vitamin E pretreatment on N-nitrosodiethylamine induced oxidative stress in rat liver. Chem Biol Interact. 2005;156:101-111.
24. Lee J, Koo N, Min DB. Reactive oxygen species, aging and antioxidant nutraceuticals. Comp Rev Food Sci Food Saf. 2004;3:21-32.
25. Moss DW, Butterworth DJ. Editors. Enzymology: biochemistry biophysics and medicine. London: Pitman Medical; 1974. p. 139.
26. Navarro J, Obrador E, Pellicer JA, Asensi M, Vina J, Estrela JM. Blood glutathione as an index of radiation-induced oxidative stress in mice and humans. Free Radic Biol Med. 1997;22:1203-1209.
27. Szatrowski TP, Nathan CF. Production of large amounts of hydrogen peroxide by human tumor cells. Cancer Res. 1991;51:794-798.
28. Kavitha K, Manoharan S. Anticarcinogenic and antilipidperoxidative effects of Tephrosia purpurea (Linn) pers. in 7,12-dimethyl benz(a)anthracene (DMBA) induced hamster buccal pouch carcinoma. Ind J Pharmacol. 2006;38:185-189.
29. Valenzuela A. The biological significance of malondialdehyde determination in the assessment of tissue oxidative stress. Life Sci. 1990;48:301-309.