Acetaldehyde production and other ADH-related characteristics of aerobic bacteria isolated from hypochlorhydric human stomach

Alcoholism: Clinical and Experimental Research

Volumn 25, Issue 3, 2001, Pages 421-426

  Väkeväinen, Satu ^a   Tillonen, Jyrki ^a   Blom, Mikko ^b   Jousimies Somer, Hannele ^b   Salaspuro, Mikko ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Acetaldehyde; Alcohol Dehydrogenase; Bacteria; Ethanol; Stomach

Indexed keywords

ACETALDEHYDE; ALCOHOL; ALCOHOL DEHYDROGENASE; CARCINOGEN; LANSOPRAZOLE;

AEROBIC BACTERIUM; ALCOHOL CONSUMPTION; ARTICLE; BACTERIAL OVERGROWTH; BACTERIUM ISOLATION; GASTROSCOPY; HUMAN; MOUTH CAVITY; NEISSERIA; NONHUMAN; PRIORITY JOURNAL; ROTHIA; STAPHYLOCOCCUS; STOMACH CANCER; STOMACH JUICE; STRAIN DIFFERENCE; STREPTOCOCCUS;

BACTERIA (MICROORGANISMS); NEISSERIA; ROTHIA; STAPHYLOCOCCUS; STREPTOCOCCUS; STREPTOCOCCUS SALIVARIUS;

EID: 0035099118     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2001.tb02230.x     Document Type: Article

References (40)

1. Alcohol and cancer
2. The effect of cimetidine treatment on ethanol formation in the human stomach
3. Laryngeal and oropharyngeal cancer, and alcohol dehydrogenase 3 and glutathione S-transferase M1 polymorphisms
4. A mutagenicity assessment of acetaldehyde
5. Expression and activities of class IV alcohol dehydrogenase and class III aldehyde dehydrogenase in human mouth
6. Studies on the intestinal flora I. The bacterial flora of the gastrointestinal tract in healthy and achlorhydric persons
7. Respiratory tract tumours in hamsters exposed to acetaldehyde vapor alone or simultaneously to benzo(a)pyrene or diethyl-nitrosamine
8. Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers
9. Increased frequency of acetaldehyde-induced sister-chromatid exchanges in human lymphocytes treated with an aldehyde dehydrogenase inhibitor
10. High acetaldehyde levels in saliva after ethanol consumption. Methodological aspects and pathogenetic implications
11. Effects of acetaldehyde on cell regeneration and differentiation of the upper gastrointestinal tract mucosa
12. Alcohol drinking
13. Acetaldehyde
14. Effect of acetaldehyde on hepatic proteins
15. High intracolonic acetaldehyde levels produced by bacteriocolonic pathway for ethanol oxidation in piglets
16. In vitro acetaldehyde formation by human colonic bacteria
17. Oxidation of ethanol to acetaldehyde by bronchopulmonary washings: Role of bacteria
18. Purification and characterization of a new alcohol dehydrogenase from human stomach
19. Genotype difference of aldehyde dehydrogenase 2 gene in alcohol drinkers influences the incidence of Japanese colorectal cancer patients
20. Acetaldehyde production by nonpathogenic Neisseria in human oral microflora: Implications for carcinogenesis in upper aerodigestive tract
21. Characteristics of aldehyde dehydrogenases of certain aerobic bacteria representing human colonic flora
22. Aldehyde dehydrogenase activity and acetate production by aerobic bacteria representing the normal flora of human large intestine
23. Metabolism of ethanol in vitro produces a compound which induces sister-chromatid exchanges in human peripheral lymphocytes in vitro: Acetaldehyde not ethanol is mutagenic
24. Contribution of oropharynx microflora and of lung microsomes to acetaldehyde in expired air after alcohol ingestion
25. Molecular characterization of microbial alcohol dehydrogenases
26. Ethanol oxidation and acetaldehyde production in vitro by human intestinal strains of Escherichia coli under aerobic, microaerobic, and anaerobic conditions
27. Binding of acetaldedehyde to rat gastric mucosa during ethanol oxidation
28. Hypothesis: Alcohol liver injury and covalent binding of acetaldehyde
29. Genetic polymorphism of alcohol dehydrogenase 2 in patients with upper aerodigestive tract cancer
30. Role of yeasts in the salivary acetaldehyde production from ethanol among risk groups for ethanol-associated oral cavity cancer
31. Formation of DNA adducts in human buccal epithelial cells exposed to acetaldehyde and methylglyoxal in vitro
32. Effect of omeprazole on intragastric bacterial counts, nitrates, nitrites, and N-nitroso compounds
33. High salivary acetaldehyde after a moderate dose of alcohol in ALDH2-deficient subjects: Strong evidence for the local carcinogenic action of acetaldehyde
34. Hypochlorhydria induced by a proton pump inhibitor leads to intragastric microbial production of acetaldehyde from ethanol
35. Alcohol and aldehyde dehydrogenases in human esophagus. Comparison with the stomach enzyme activities
36. Esophageal cancer and aldehyde dehydrogenase-2 genotypes in Japanese males
37. Multiple primary esophageal and concurrent upper aerodigestive tract cancer and aldehyde dehydrogenase-2 genotype of Japanese alcoholics
38. Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholics
39. Cancer screening of upper aerodigestive tract cancers in Japanese alcoholics with reference to drinking and smoking habits and aldehyde dehydrogenase-2 genotype