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Volumn 8, Issue 1, 2007, Pages 1-3

Role of CYP2D6 testing in selection of endocrine therapy for breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYTAMOXIFEN; ANTIDEPRESSANT AGENT; AROMATASE INHIBITOR; CYTOCHROME P450 2D6; DRUG METABOLITE; ENDOXIFEN; EXEMESTANE; FLUOXYMESTERONE; NORADRENALIN UPTAKE INHIBITOR; PAROXETINE; SEROTONIN UPTAKE INHIBITOR; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 33846552983     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/14622416.8.1.1     Document Type: Editorial
Times cited : (8)

References (27)
  • 1
    • 0038303307 scopus 로고    scopus 로고
    • What can oncologists learn from HIV?
    • Stebbing J, Bower M: What can oncologists learn from HIV? Lancet Oncol. 4, 438-445 (2003).
    • (2003) Lancet Oncol. , vol.4 , pp. 438-445
    • Stebbing, J.1    Bower, M.2
  • 2
    • 29744459471 scopus 로고    scopus 로고
    • Comparative pharmacogenomics of antiretroviral and cytotoxic, treatments
    • Stebbing J, Bower M: Comparative pharmacogenomics of antiretroviral and cytotoxic, treatments. Lancet Oncol. 7, 61-68 (2006).
    • (2006) Lancet Oncol. , vol.7 , pp. 61-68
    • Stebbing, J.1    Bower, M.2
  • 3
    • 33749013547 scopus 로고    scopus 로고
    • A review of the ethnic differences in breast cancer
    • Bowen RL, Stebbing J, Jones LJ: A review of the ethnic differences in breast cancer: Pharmacogenomics, 935-942 (2006).
    • (2006) Pharmacogenomics , pp. 935-942
    • Bowen, R.L.1    Stebbing, J.2    Jones, L.J.3
  • 4
    • 0034074170 scopus 로고    scopus 로고
    • Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or low CYP2D6 activity
    • Hamelin BA, Bouayad A, Methot J et al.: Significant interaction between the nonprescription antihistamine diphenhydramine and the CYP2D6 substrate metoprolol in healthy men with high or low CYP2D6 activity. Clin. Pharmol. Ther. 67, 466-477 (2000).
    • (2000) Clin. Pharmol. Ther. , vol.67 , pp. 466-477
    • Hamelin, B.A.1    Bouayad, A.2    Methot, J.3
  • 5
    • 0031043162 scopus 로고    scopus 로고
    • The control of breast cancer: The role of tamoxifen
    • Forbes JF: The control of breast cancer: the role of tamoxifen. Semin. Oncol. 24, S1-5-S1-19 (1997).
    • (1997) Semin. Oncol. , vol.24
    • Forbes, J.F.1
  • 6
    • 2942544830 scopus 로고    scopus 로고
    • Tamoxifen resistance by a conformational arrest of the estrogen receptor α after PKA activation in breast cancer
    • Michalides R, Griekspoor A, Balkenende A et al.: Tamoxifen resistance by a conformational arrest of the estrogen receptor α after PKA activation in breast cancer. Cancer Cell 5, 597-605 (2004).
    • (2004) Cancer Cell , vol.5 , pp. 597-605
    • Michalides, R.1    Griekspoor, A.2    Balkenende, A.3
  • 7
    • 19344364880 scopus 로고    scopus 로고
    • Effects ofthemotherapy and hormonal ffierapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG): Effects ofthemotherapy and hormonal ffierapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet 365, 1687-1717 (2005).
    • (2005) Lancet , vol.365 , pp. 1687-1717
  • 9
    • 0024584001 scopus 로고
    • Distribution of 4-hydro)-N-desmethyltamoxifen and other tamoxifen metabolites in human biological fluids during tamoxifen treatment
    • Lien EA, Solheim E, Lea OA, Lundgren S, Kvinnsland S. Ueland PM: Distribution of 4-hydro)-N-desmethyltamoxifen and other tamoxifen metabolites in human biological fluids during tamoxifen treatment. Cancer Res. 49, 2175-2183 (1989).
    • (1989) Cancer Res. , vol.49 , pp. 2175-2183
    • Lien, E.A.1    Solheim, E.2    Lea, O.A.3    Lundgren, S.4    Kvinnsland, S.5    Ueland, P.M.6
  • 11
    • 18544389188 scopus 로고    scopus 로고
    • The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver
    • Coller JK, Krebsfaenger N, Klein K et al.: The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver. & J Clin. Pharmacol. 54, 157-167 (2002).
    • (2002) Br. J. Clin. Pharmacol. , vol.54 , pp. 157-167
    • Coller, J.K.1    Krebsfaenger, N.2    Klein, K.3
  • 12
    • 3342932419 scopus 로고    scopus 로고
    • Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen
    • Johnson MD, Zuo H. Lee KH et al.: Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen. Breast Cancer Res. Treat. 85. 151-159 (2004).
    • (2004) Breast Cancer Res. Treat. , vol.85 , pp. 151-159
    • Johnson, M.D.1    Zuo, H.2    Lee, K.H.3
  • 13
    • 0346602691 scopus 로고    scopus 로고
    • Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine
    • Stearns V, Johnson MD, Rae JM et al: Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. J. Natl Cancer Inst. 95, 1758-1764 (2003).
    • (2003) J. Natl Cancer Inst. , vol.95 , pp. 1758-1764
    • Stearns, V.1    Johnson, M.D.2    Rae, J.M.3
  • 14
    • 0036124107 scopus 로고    scopus 로고
    • CYPD2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford LD: CYPD2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 3, 229-243 (2002).
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 15
    • 19944434201 scopus 로고    scopus 로고
    • CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment
    • Jin Y, Desta Z, Stearns V et al.: CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. J Natl Cancer Inst. 97, 30-39 (2005).
    • (2005) J. Natl Cancer Inst. , vol.97 , pp. 30-39
    • Jin, Y.1    Desta, Z.2    Stearns, V.3
  • 16
    • 33644639136 scopus 로고    scopus 로고
    • Pharmacogenetics of tamoxifen biotransfotmation is associated with clinical outcomes of efficacy and hot flashes
    • Goetz W, Rae JM, Suman VJ et al.: Pharmacogenetics of tamoxifen biotransfotmation is associated with clinical outcomes of efficacy and hot flashes. J. Clin. Oncol. 23, 9312-9318 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 9312-9318
    • Goetz, W.1    Rae, J.M.2    Suman, V.J.3
  • 17
    • 33745926220 scopus 로고    scopus 로고
    • Randomized trial of tamoxifen alone or combined with fluoxymesterone as adjuvant therapy in postmenopausal women with resected estrogen receptor positive breast cancer
    • North Central Cancer Treatment Group Trial 89-30-52
    • Ingle JN, Suman VJ, Maiward JA et al.: Randomized trial of tamoxifen alone or combined with fluoxymesterone as adjuvant therapy in postmenopausal women with resected estrogen receptor positive breast cancer. North Central Cancer Treatment Group Trial 89-30-52. Breast Cancer Res. Treat. 98, 217-222 (2006).
    • (2006) Breast Cancer Res. Treat. , vol.98 , pp. 217-222
    • Ingle, J.N.1    Suman, V.J.2    Maiward, J.A.3
  • 18
    • 33747045564 scopus 로고    scopus 로고
    • Polymorphism in the CYP2D6 tamoxifen-metabolizing gene influences clinical effect but not hot flashes: Data from the Italian Tamoxifen Trial
    • Bonanni B, Macis D. Maisonneuve P et al: Polymorphism in the CYP2D6 tamoxifen-metabolizing gene influences clinical effect but not hot flashes: data from the Italian Tamoxifen Trial. J. Clin. Oncol. 24, 3708-3709 (2006).
    • (2006) J. Clin. Oncol. , vol.24 , pp. 3708-3709
    • Bonanni, B.1    Macis, D.2    Maisonneuve, P.3
  • 19
    • 29144491089 scopus 로고    scopus 로고
    • Genotype of metabolic enzymes and the benefit of tamoxifen in postmenopausal breast cancer patients
    • Wegman P, Vatnikka L, Stal O et al.: Genotype of metabolic enzymes and the benefit of tamoxifen in postmenopausal breast cancer patients. Breast Cancer Res 7, R284-R290 (2005).
    • (2005) Breast Cancer Res , vol.7
    • Wegman, P.1    Vatnikka, L.2    Stal, O.3
  • 21
    • 21344467511 scopus 로고    scopus 로고
    • Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients
    • Nowell SA, Ahn J, Rae JM et al.: Association of genetic variation in tamoxifen-metabolizing enzymes with overall survival and recurrence of disease in breast cancer patients. Breast Cancer Res Treat. 91, 249-258 (2005).
    • (2005) Breast Cancer Res Treat. , vol.91 , pp. 249-258
    • Nowell, S.A.1    Ahn, J.2    Rae, J.M.3
  • 22
    • 33745347897 scopus 로고    scopus 로고
    • Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: Implication for optimization of breast cancer treatment
    • Borges S, Desta Z, Li L et al: Quantitative effect of CYP2D6 genotype and inhibitors on tamoxifen metabolism: implication for optimization of breast cancer treatment. Clin. Pharmacol Ther. 80, 61-74 (2006).
    • (2006) Clin. Pharmacol Ther. , vol.80 , pp. 61-74
    • Borges, S.1    Desta, Z.2    Li, L.3
  • 23
    • 0034676813 scopus 로고    scopus 로고
    • Venlafaxine in management of hot flashes in survivors of breast cancer: A randomised controlled trial
    • Loprinzi CL, Kugler JW, Sloan JA et al.: Venlafaxine in management of hot flashes in survivors of breast cancer: a randomised controlled trial. Lancet 356, 2059-2063 (2000).
    • (2000) Lancet , vol.356 , pp. 2059-2063
    • Loprinzi, C.L.1    Kugler, J.W.2    Sloan, J.A.3
  • 24
    • 0037087582 scopus 로고    scopus 로고
    • Phase III evaluation of fluoxetine for treatment of hot flashes
    • Loprinzi CL, Sloan JA, Perez EA et al: Phase III evaluation of fluoxetine for treatment of hot flashes. J Clin. Oncol. 20, 1578-1583 (2002).
    • (2002) J Clin. Oncol. , vol.20 , pp. 1578-1583
    • Loprinzi, C.L.1    Sloan, J.A.2    Perez, E.A.3
  • 25
    • 0037976797 scopus 로고    scopus 로고
    • Paroxetine controlled release in the treatment of menopausal hot flashes: A randomized controlled trial
    • Steams V, Beebe KL, Iyengar M, Dube E: Paroxetine controlled release in the treatment of menopausal hot flashes: a randomized controlled trial. JAMA. 289, 2827-2834 (2003).
    • (2003) JAMA , vol.289 , pp. 2827-2834
    • Steams, V.1    Beebe, K.L.2    Iyengar, M.3    Dube, E.4
  • 26
    • 33847034287 scopus 로고    scopus 로고
    • The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen
    • (Epub ahead of print)
    • Goetz MP, Knox SK, Suman VJ et al.: The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen. Breast Cancer Res. Treat. (2006) (Epub ahead of print).
    • (2006) Breast Cancer Res. Treat.
    • Goetz, M.P.1    Knox, S.K.2    Suman, V.J.3
  • 27
    • 10744223655 scopus 로고    scopus 로고
    • A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
    • Coombes RC, Hall E. Gibson LJ et al: A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N. Engl. J. Med. 350, 1081-1092 (2004).
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1081-1092
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.