Vaccinia virus A6L encodes a virion core protein required for formation of mature virion

Journal of Virology

Volumn 81, Issue 3, 2007, Pages 1433-1443

  Meng, Xiangzhi ^a   Embry, Addie ^a   Sochia, Debbi ^a   Xiang, Yan ^a  

^a Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CORE PROTEIN; PROTEIN A6; UNCLASSIFIED DRUG;

A6L GENE; ARTICLE; DNA REPLICATION; ELECTRON MICROSCOPE; GENE EXPRESSION; GENETIC CONSERVATION; NONHUMAN; PHENOTYPE; POXVIRUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN STABILITY; TEMPERATURE SENSITIVE MUTANT; THERMOSTABILITY; VACCINIA VIRUS; VIRION; VIROGENESIS; VIRUS GENE; VIRUS MORPHOGENESIS; VIRUS RECOMBINANT; VIRUS REPLICATION;

CELL LINE; GENES, VIRAL; OPEN READING FRAMES; TRANSCRIPTION, GENETIC; VACCINIA VIRUS; VIRAL CORE PROTEINS; VIRION;

VACCINIA VIRUS; VERTEBRATA;

EID: 33846549360     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02206-06     Document Type: Article

References (26)

1. Chung, C. S., C. H. Chen, M. Y. Ho, C. Y. Huang, C. L. Liao, and W. Chang. 2006. Vaccinia virus proteome: identification of proteins in vaccinia virus intracellular mature virion particles. J. Virol. 80:2127-2140.
2. Condit, R. C., N. Moussatche, and P. Traktman. 2006. In a nutshell: structure and assembly of the vaccinia virion. Adv. Virus Res. 66:31-124.
3. da Fonseca, F. G., A. S. Weisberg, M. F. Caeiro, and B. Moss. 2004. Vaccinia virus mutants with alanine substitutions in the conserved G5R gene fail to initiate morphogenesis at the nonpermissive temperature. J. Virol. 78:10238-10248.
4. DeMasi, J., and P. Traktman. 2000. Clustered charge-to-alanine mutagenesis of the vaccinia virus H5 gene: isolation of a dominant, temperature-sensitive mutant with a profound defect in morphogenesis. J. Virol. 74:2393-2405.
5. Earl, P. L., B. Moss, L. S. Wyatt, and M. W. Carroll. 1998. Generation of recombinant vaccinia viruses, p. 16.17.1-16.17.19. In F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.), Current protocols in molecular biology. John Wiley & Sons, Inc., Hoboken, NJ.
6. Falkner, F. G., and B. Moss. 1990. Transient dominant selection of recombinant vaccinia viruses. J. Virol. 64:3108-3111.
7. Garcia, A. D., and B. Moss. 2001. Repression of vaccinia virus Holliday junction resolvase inhibits processing of viral DNA into unit-length genomes. J. Virol. 75:6460-6471.
8. Grubisha, O., and P. Traktman. 2003. Genetic analysis of the vaccinia virus 16 telomere-binding protein uncovers a key role in genome encapsidation. J. Virol. 77:10929-10942.
9. Hassett, D. E., and R. C. Condit. 1994. Targeted construction of temperature-sensitive mutations in vaccinia virus by replacing clustered charged residues with alanine. Proc. Natl. Acad. Sci. USA 91:4554-4558.
10. Ishii, K., and B. Moss. 2001. Role of vaccinia virus A20R protein in DNA replication: construction and characterization of temperature-sensitive mutants. J. Virol. 75:1656-1663.
11. Kato, S. E. M., F. A. B. Greco, C. R. A. Damaso, R. C. Condit, and N. Moussatche. 2004. An alternative genetic method to test essential vaccinia virus early genes. J. Virol. Methods 115:31-40.
12. Katz, E., and B. Moss. 1970. Formation of a vaccinia virus structural polypeptide from a higher molecular weight precursor: inhibition by rifampicin. Proc. Natl. Acad. Sci. USA 66:677-684.
13. McCraith, S., T. Holtzman, B. Moss, and S. Fields. 2000. Genome-wide analysis of vaccinia virus protein-protein interactions. Proc. Natl. Acad. Sci. USA 97:4879-4884.
14. Meng, X., M. Leman, and Y. Xiang. 15, September 2006, posting date. Variola virus IL-18 binding protein interacts with three human IL-18 residues that are part of a binding site for human IL-18 receptor alpha subunit. Virology doi:10.1016/j.virol.2006.08.019.
15. Meng, X., and Y. Xiang. 2006. Vaccinia virus K1L protein supports viral replication in human and rabbit cells through a cell-type-specific set of its ankyrin repeat residues that are distinct from its binding site for ACAP2. Virology 353:220-233.
16. Moss, B. 2001. Poxviridae: the viruses and their replication, p. 2849-2883. In D. M. Knipe and P. M. Howley (ed.), Fields virology, 4th ed., vol. 2. Lippincott Williams & Wilkins, Philadelphia, PA.
17. Niles, E. G., and J. Seto. 1988. Vaccinia virus gene D8 encodes a virion transmembrane protein. J. Virol. 62:3772-3778.
18. Punjabi, A., K. Boyle, J. DeMasi, O. Grubisha, B. Unger, M. Khanna, and P. Traktman. 2001. Clustered charge-to-alanine mutagenesis of the vaccinia virus A20 gene: temperature-sensitive mutants, have a DNA-minus phenotype and are defective in the production of processive DNA polymerase activity. J. Virol. 75:12308-12318.
19. Ravanello, M. P., C. A. Franke, and D. E. Hruby. 1993. An NH2-terminal peptide from the vaccinia virus L1R protein directs the myristylation and virion envelope localization of a heterologous fusion protein. J. Biol. Chem. 268:7585-7593.
20. Rodriguez, J. F., E. Paez, and M. Esteban. 1987. A 14,000-Mr envelope protein of vaccinia virus is involved in cell fusion and forms covalently linked trimers. J. Virol. 61:395-404.
21. Rosel, J., and B. Moss. 1985. Transcriptional and translational mapping and nucleotide sequence analysis of a vaccinia virus gene encoding the precursor of the major core polypeptide 4b. J. Virol. 56:830-838.
22. Sakhatskyy, P., S. Wang, T. H. Chou, and S. Lu. 2006. Immunogenicity and protection efficacy of monovalent and polyvalent poxvirus vaccines that include the D8 antigen. Virology 355:164-174.
23. Upton, C., S. Slack, A. L. Hunter, A. Ehlers, and R. L. Roper. 2003. Poxvirus orthologous clusters: toward defining the minimum essential poxvirus genome. J. Virol. 77:7590-7600.
24. Ward, G., C. Stover, B. Moss, and T. Fuerst. 1995. Stringent chemical and thermal regulation of recombinant gene expression by vaccinia virus vectors in mammalian cells. Proc. Natl. Acad. Sci. USA 92:6773-6777.
25. Yoder, J. D., T. S. Chen, C. R. Gagnier, S. Vemulapalli, C. S. Maier, and D. E. Hruby. 2006. Pox proteomics: mass spectrometry analysis and identification of vaccinia virion proteins. Virol. J. 3:10.
26. Zachertowska, A., D. Brewer, and D. H. Evans. 2006. Characterization of the major capsid proteins of myxoma virus particles using MALDI-TOF mass spectrometry. J. Virol. Methods 132:1-12.