Paraquat-induced apoptotic cell death in lung epithelial cells

Tuberculosis and Respiratory Diseases

Volumn 61, Issue 4, 2006, Pages 366-373

  Song, Tak Ho ^a   Yang, Joo Yeon ^a   Jeong, In Kook ^a   Park, Jae Seok ^a   Jee, Young Koo ^a   Kim, Youn Seup ^a   Lee, Kye Young ^b  

^a Dankook University   (South Korea)

^b Konkuk University Hospital   (South Korea)

Author keywords

Apoptosis; Bcl 2; Dexamethasone; N acetylcysteine; Paraquat

Indexed keywords

ACETYLCYSTEINE; DEXAMETHASONE; LIPOCORTIN 5; PARAQUAT; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM;

EID: 33846514026     PISSN: 17383536     EISSN: None     Source Type: Journal    
DOI: 10.4046/trd.2006.61.4.366     Document Type: Article

References (28)

1. Aldrich TK, Fisher AB, Cadenas E, Chance B. Evidence for lipid peroxidation by paraquat in the perfused rat lung. J Lab Clin Med 1983;101:66-73.
2. Skillrud DM, Martin WJ 2nd. Paraquat-induced injury of type II alveolar cells. Am Rev Respir Dis 1984;129:995-9.
3. TH Lee, SW Yang, TG LEE, SY Choi, YW Lee, KY Lee, Therapeutic effect of hemoperfusion in paraquat poisoning patients. Kor J Int Med 1997;52:114-9.
4. SI Lee, KW Ahn, CH Chung, The effect of aminotriazole on pulmonaty toxicity of paraquat poisoning. Tuber Respir Dis 1994;41:222-30.
5. Uhal BD, Joshi L, True AL, Mundle S, Raza A, Pardo A, et al. Fibroblasts isolated after fibrotic lung injury induce apoptosis of alveolar epithelial cells in vitro. Am J Physiol 1995;269:L819-28.
6. Kitamura Y, Hashimoto S, Mizuta N, Kobayashi A, Kooguchi K, Fujiwara I, et al. Fas/FasL-dependent apoptosis of alveolar cells after lipopolysaccharide- induced lung injury in mice. Am J Respir Crit Care Med 2001;163:762-9.
7. EK Mo, JH Lee, CG Yoo, YW Kim, K Han, et al. The effect of TNF-α gene trasfer on chemosensitivity in lung cancer cells. Reports of Korean Tuberculosis Research Center 1996;7:29-54.
8. Dusinska M, Kovacilova Z, Vallova B, Collins A. Responses of alveolar macrophages and epithelial type II cells to oxidative DNA damage caused by paraquat. Carcinogenesis 1998;19:809-12.
9. Mossman BT, Gee JB. Pulmonary reactions and mechanisms of toxicity of inhaled fibers. Toxicol Appl Pharmacol 1988;93:472-83.
10. Rose MS, Smith LL, Wyatt I. Evidence for energy-dependent accumulation of paraquat into rat lung. Nature 1974;252:314-5.
11. Hagimoto N, Kuwano K, Nomoto Y, Kunitake R, Hara N. Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol 1997;16:91-101.
12. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, et al. The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149:818-24.
13. Cox G, Crossley J, Xing Z. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am J Respir Cell Mol Biol 1995;12:232-7.
14. Woo D. Apoptosis and loss of renal tissue in polycystic kidney disease. N Engl J Med 1995;333:18-25.
15. Hashimoto S, Kobayashi A, Kooguchi K, Kitamura Y, Onodera H, Nakajima H. Upregulation of two death pathways of perforin/granzyme and FasL/Fas in septic acute respiratory distress syndrome. Am J Respir Crit Care Med 2000;161:237-43.
16. Matute G, Liles WC, Radella F, Steinberg KP, Ruzinski JT, Jonas M, et al. Neutrophil apoptosis in the acute respiratory distress syndrome. Am J Respir Crit Care Med 1997;156:1969-77.
17. Matthay MA, Wiener-Kronish JP. Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 1990;142:1250-7.
18. Svee K, White J, Vaillant P, Jessurun J, Roongta U, Krumwlede M, et al. Acute lung injury fibroblast migration and invasion of a fibrin matrix is medigated by CD44. J Clin Invest 1996;98:1713-27.
19. Auphan N, Didonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 1995;270:286-90.
20. KY Lee, YS Kim, MH Ko, JS Park, YK Jee, KY Kim. Dexamethasone-induced inhibition of NF-κB transactivation in lung epithelial cells. Tuber Respir Dis 2000;48:682-98.
21. Rahma I, Li XY, Donaldson K, Harrison DJ, MacNee W. Glutathione homeostasis in alveolar epithelial cells in vitro and lung in vivounder oxidative stress. Am J Physiol 1995;269:L285-92.
22. Bailly-Maitre B, Sousa G, Boulukos K, Gugenheim J, Rahmani R. Dexamethasone inhibits spontaneous apoptosis in primary cultures of human and rat hepatocytes via Bcl-2 and Bcl-xL induction. Cell Death Differ 2001;8:279-88.
23. Fassina G, Giunciuglio D, Aluigi MG, Cai T, Masiello L, Dagostino F, et al. Inhibition of angiogenesis and protection from apoptosis by N-acetylcysteine. Cancer Detect Prev 1998;22:125-6.
24. Hoffer E, Avidor I, Benjaminov O, Shenker L, Tabak A, Tamir A, et ai. N-acetylcysteine delays the infiltration of inflammatory cells into the lungs of paraquat intoxicated rats. Toxicol Appl Pharmacol 1993;120:8-12.
25. Hoffer E, Baum Y, Tabak A, Taitelman U. N-acetylcysteine increases the glutathione content and protects rat alveolar type II cells against paraquat-induced cytotoxicity. Toxicol Lett 1996;84:7-12.
26. Fabisiak JP, Kagan VE, Ritov VB, Jonhson DE, Lazo JS. Bcl-2 inhibits selective oxidation and externalization of phosphatidylserine during paraquat-induced apoptosis. Am J Physiol 1997;272:C675-84.
27. Rimpler MM, Rauen U, Schmidt T, Moray T, de Groot H. Protection against hydrogen peroxide cytotoxicity in Rat-1 fibroblasts provided by the oncoprotein Bcl-2: maintenance of calciumhomeostasis is secondary to the effect of Bcl-2 on cellular glutathione. Biochem J 1999;340:291-7.
28. Guinee D Jr, Brambilla E, Fleming M, Hayashi T, Rahn M, Koss M, et al. The potential role of Bax and Bcl-2 expression in diffuse alveolar damage. Am J Pathol 1997;151:999-1007.