Systems biology: Potential to improve decision making in pharmaceutical development

Drug News and Perspectives

Volumn 19, Issue 9, 2006, Pages 575-583

  Mujagic, Hamza ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPTERIN; CANERTINIB; CYCLIC AMP; DIMAPRIT; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; LAPATINIB; NEUTROPHIL CYTOPLASMIC ANTIBODY; PROTEIN TYROSINE KINASE;

BLOOD VESSEL INJURY; CANCER THERAPY; CONFERENCE PAPER; DECISION MAKING; DRUG INDUSTRY; DRUG RESEARCH; GENE ACTIVATION; GENE EXPRESSION; GENE INTERACTION; MEDICAL RESEARCH;

ANTINEOPLASTIC AGENTS; DECISION MAKING; DRUG DESIGN; GENE EXPRESSION PROFILING; HUMANS; MODELS, GENETIC; NEOPLASMS; PROTEIN-TYROSINE KINASES; SYSTEMS BIOLOGY; VASCULAR DISEASES;

EID: 33846478651     PISSN: 02140934     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (5)

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2. Isaacs, J.F., Hasty, J., Cantor, R.C. and Collins, J.J. Prediction and measurement of an autoregulatory genetic module. Proc Natl Acad Sci U S A 2003, 100(13): 7714-9.
3. Rush, J., Moritz, A., Lee, K.A. et al. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Nature Biotechnol 2005, 23(1): 94-101.
4. Brott, D., Jones, H., Schoefild, J. et al. Biomarkers of drug-induced vascular injury. Toxicol Appl Pharmacol 2005, 207(2 Suppl.): 441-5.
5. Butcher, C.E., Berg, L.E. and Kunkel, J.E. Systems Biology in drug discovery. Nature Biotechnol 2004, 22(10): 1253-9.