Simple reversed-phase liquid chromatographic assay for simultaneous quantification of free mycophenolic acid and its glucuronide metabolite in human plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 846, Issue 1-2, 2007, Pages 313-318

  Yau, Wai Ping ^a   Vathsala, Anantharaman ^b   Lou, Huei Xin ^b   Zhou, Shu Feng ^a   Chan, Eli ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

Free drug; Human plasma; Mycophenolic acid; Mycophenolic acid glucuronide; Reversed phase HPLC

Indexed keywords

FREE DRUG; HUMAN PLASMA; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID GLUCURONIDE;

BIOASSAY; BODY FLUIDS; CARBOXYLIC ACIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES; PLASMAS; ULTRAFILTRATION;

DRUG PRODUCTS;

ACARBOSE; ACETYLSALICYLIC ACID; ACICLOVIR; AMLODIPINE; ATENOLOL; BEZAFIBRATE; CAPTOPRIL; CYCLOSPORIN; DILTIAZEM; DIPYRIDAMOLE; ENALAPRIL; FUROSEMIDE; GANCICLOVIR; GLIPIZIDE; HYDRALAZINE; IMIDAPRIL; INDAPAMIDE; ISOSORBIDE DINITRATE; LOSARTAN; MYCOLIC ACID; MYCOLIC ACID GLUCURONIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NIFEDIPINE; PRAVASTATIN; PRAZOSIN; PREDNISOLONE; SIMVASTATIN; TACROLIMUS; UNCLASSIFIED DRUG; UNINDEXED DRUG; WARFARIN;

ACCURACY; ADULT; ARTICLE; CASE REPORT; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG GLUCURONIDATION; DRUG ISOLATION; HUMAN; MALE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY AND SPECIFICITY; ULTRAFILTRATION; VALIDATION STUDY;

CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MYCOPHENOLIC ACID; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROPHOTOMETRY, ULTRAVIOLET; ULTRAFILTRATION;

EID: 33846442061     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2006.07.062     Document Type: Article

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