Childhood-onset bipolar disorder: Evidence for increased familial loading of psychiatric illness

Journal of the American Academy of Child and Adolescent Psychiatry

Volumn 46, Issue 2, 2007, Pages 197-204

  Rende, Richard ^a,e   Birmaher, Boris ^b   Axelson, David ^b   Strober, Michael ^c   Gill, Mary Kay ^b   Valeri, Sylvia ^a   Chiappetta, Laurel ^b   Ryan, Neal ^b   Leonard, Henrietta ^a   Hunt, Jeffrey ^a   Iyengar, Satish ^d   Keller, Martin ^a  

^a BROWN UNIVERSITY   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e BUTLER HOSPITAL   (United States)

Author keywords

Age at onset; Bipolar disorder; Childhood; Family history

Indexed keywords

ADOLESCENT; AGE DISTRIBUTION; ANXIETY DISORDER; ARTICLE; ATTENTION DEFICIT DISORDER; BIPOLAR DISORDER; COMPARATIVE STUDY; CONDUCT DISORDER; CONTROLLED STUDY; DEMOGRAPHY; DEPRESSION; FAMILIAL DISEASE; FAMILY HISTORY; FEMALE; HUMAN; INTERVIEW; MAJOR CLINICAL STUDY; MALE; ONSET AGE; PRIORITY JOURNAL; RELATIVE; SCHOOL CHILD; SCREENING; SUBSTANCE ABUSE; SUICIDAL BEHAVIOR;

ADOLESCENT; AGE FACTORS; BIPOLAR DISORDER; CHILD; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; GENOTYPE; HUMANS; MALE; MENTAL DISORDERS; PHENOTYPE;

EID: 33846441253     PISSN: 08908567     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.chi.0000246069.85577.9e     Document Type: Article

References (27)

1. Althoff RR, Faraone SV, Rettew DC, Morler CP, Hudziak JJ (2005), Family, twin, adoption, and molecular genetic studies of juvenile bipolar disorder. Bipolar Disord 7:598-609
2. American Psychiatric Association (1994), Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV). Washington, DC: American Psychiatric Association
3. Axelson D, Birmaher B, Brent D et al. (2003), A preliminary study of the K-SADS Mania Rating Scale for children and adolescents. J Child Adolesc Psychiatry 36:980-988
4. Axelson D, Birmaher BStrober M et al. (2006), Phenomenology of children and adolescents with bipolar spectrum disorders. Arch Gen Psychiatry 63:1139-1148
5. Birmaher B, Axelson D, Strober M et al. (2006), Clinical course of children and adolescents with bipolar spectrumdisorders. Arch Gen Psychiatry 63:175-183
6. Bromet EJ, Finch SJ, Carlson GA et al. (2005), Time to remission and relapse after the first hospital admission in severe bipolar disorder. Soc Psychiatry Psychiatr Epidemiol 40:106-113
7. Carlson GA, Bromet EJ, Driessens C, Mojtabai R, Schwartz JE (2002), Age at onset, childhood psychopathology, and 2-year outcome in psychotic bipolar disorder. Am J Psychiatry 159:307-309
8. Chambers WJ, Puig-Antich J, Hirsch M et al. (1985), The assessment of affective disorders in children and adolescents by semi-structured interview test-retest reliability. Arch Gen Psychiatry 42:696-702
9. Craney JL, Geller B (2005), A prepubertal and early adolescent bipolar disorder-I phenotype: review of phenomenology and longitudinal course. Bipolar Disord 5:243-256
10. Faraone SV, Glatt SJ, Tsuang MT (2003), The genetics of pediatric-onset bipolar disorder. Biol Psychiatry 53:970-977
11. First MB, Spitzer RL, Williams JBW, Gibbon M (1995), Structured Clinical Interview for DSM-IV (SCID). Washington, DC: American Psychiatric Association
12. Geller B, Tillman R (2005), Prepubertal and early adolescent bipolar I disorder: review of diagnostic validation by Robins and Guze criteria. J Clin Psychiatry 66:21-28
13. Geller B, Tillman R, Craney JL, Bolhofner K (2004), Four-year prospective outcome and natural history of mania in children with a prepubertal and early adolescent bipolar disorder phenotype. Arch Gen Psychiatry 61:459-467
14. Kaufman J, Birmaher B, Brent D et al. (1997), Schedule for affective disorders and schizophrenia for school-age children: present version and lifetime version (K-SADS-PL): initial reliability and validity data. J Am Acad Child Adolesc Psychiatry 36:980-988
15. Leboyer M, Henry C, Paillere-Martinot ML, Bellvier F (2005), Age at onset in bipolar affective disorders: a review. Bipolar Dis 7:111-118
16. Lin PI, McInnis MG, Potash JB et al. (2006), Clinical correlates and familial aggregation of age at onset in bipolar disorder. Am J Psychiatry 163:240-246
17. Mick E, Biederman J, Faraone SV, Murray K, Wozniak J (2003), Defining a developmental subtype of bipolar disorder in a sample of nonreferred adults by age at onset. J Child Adolesc Psychopharmacol 13:453-462
18. Neuman RJ, Geller B, Rice JP, Todd RD (1997), Increased prevalence and earlier onset of mood disorders among relatives of prepubertal versus adult probands. J Am Acad Child Adolesc Psychiatry 36:466-473
19. Pauls DL, Morton LA, Egeland JA (1992), Risks of affective illness among first-degree relatives of bipolar I old-order Amish probands. Arch Gen Psychiatry 49:703-708
20. Pavuluri MN, Birmaher B, Naylor MW (2005), Pediatric bipolar disorder: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry 44:846-871
21. Perlis RH, Miyahara S, Marangell LB et al. (2004), Long-term implications of early onset in bipolar disorder: data from the first 1000 participants in the systematic treatment enhancement program for bipolar disorder (SEP-BP). Biol Psychiatry 55:875-881
22. Rende R, Waldman I (2006), Behavioral and molecular genetics and developmental psychopathology. In: Developmental Psychopathology, Vol. 2: Developmental Neuroscience, 2nd edition, Cicchetti D, Cohen D, eds. New York: Wiley, pp 427-464
23. Rende R, Weissman MM (1999), Assessment of family history of psychiatric disorder. In: Diagnostic Assessment in Child and Adolescent Psychopathology, Shaffer D, Lucas CP, Richters JE, eds. New York: The Guilford Press, pp 230-255
24. Rice JP, Reich T, Andreasen NC et al. (1987), The familial transmission of bipolar illness. Arch Gen Psychiatry 44:441-447
25. Strober M (1992), Relevance of early age-of-onset in genetic studies of bipolar affective disorder. J Am Acad Child Adolesc Psychiatry 31:606-610
26. Strober M, Morrell W, Burroughs J, Lampert C, Danforth H, Freeman R (1988), A family study of bipolar I disorder in adolescence: early onset of symptoms linked to increased familial loading and lithium resistance. J Affect Disord 15:255-268
27. Weissman MM, Wickramaratne P, Adams PA, Wolk S, Verdeli H, Olfson M (2000), Brief screening for family psychiatric history. Arch Gen Psychiatry 57:675-682