In vitro and in vivo activities of leukotriene B4-loaded biodegradable microspheres

Prostaglandins and Other Lipid Mediators

Volumn 83, Issue 1-2, 2007, Pages 121-129

  Nicolete, Roberto ^a   Lima, Karla de Melo ^a,b   Júnior, José M R ^b   Baruffi, Marcelo D ^a   de Medeiros, Alexandra I ^a   Bentley, Maria V L B ^a   Silva, Célio L ^a   Faccioli, Lúcia H ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Nanocore Biotecnologia Ltda   (Brazil)

Author keywords

Chemotaxis analysis; In vivo inflammatory cells recruitment; Leukotriene B4; Microspheres polylactic acid polyglycolic acid copolymer

Indexed keywords

LEUKOTRIENE B4; MICROSPHERE; POLYGLACTIN;

ANIMAL CELL; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; DRUG RELEASE; DRUG UPTAKE; MACROPHAGE ACTIVATION; MALE; MICROENCAPSULATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERITONEUM MACROPHAGE;

ANIMALS; CHEMOTAXIS, LEUKOCYTE; GLYCOLATES; HUMANS; INFLAMMATION; LEUKOTRIENE B4; MACROPHAGES, PERITONEAL; MALE; MICE; MICROSPHERES; MODELS, THEORETICAL; NEUTROPHILS; PARTICLE SIZE; PULMONARY ALVEOLI;

EID: 33846437128     PISSN: 10988823     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prostaglandins.2006.10.007     Document Type: Article

References (25)

1. Canetti C., Silva J.S., Ferreira S.H., and Cunha F.Q. Tumour necrosis factor-alpha and leukotriene B(4) mediate the neutrophil migration in immune inflammation. Br J Pharmacol 134 (2001) 1619-1628
2. 111In-eosinophils induced by inflammatory mediators, in vivo. Immunology 73 (1991) 222-227
3. 4 and BLT1 control cytotoxic effector T cell recruitment to inflamed tissues. Nat Immunol 4 (2003) 965
4. Medeiros A.I., SÁ-Nunes A., Soares E.G., Peres C.M., Silva C.L., and Faccioli L.H. Blockade of endogenous leukotrienes exacerbates pulmonary histoplasmosis. Infect Immun (2004) 1637-1644
5. Machado E.R., Ueta M.T., Lourenço E.V., et al. Leukotrienes play a role in the control of parasite burden in murine strongyloidiasis. J Immunol 175 (2005) 3892-3899
6. 4 augments neutrophil phagocytosis of Klebsiella pneumoniae. Infect Immun 69 (2001) 2011
7. Serezani C.H., Aronoff D.M., Jancar S., Mancuso P., and Peters-Golden M. Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidase. Blood 106 (2005) 1067-1075
8. Malaviya R., and Abraham S.N. Role of mast cell leukotrienes in neutrophil recruitment and bacterial clearance in infectious peritonitis. J Leuk Biol 67 (2000) 841
9. 4 to humans. J Infect Dis 189 (2004) 2001-2009
10. 4. Clin Exp Immunol 126 (2001) 494-502
11. Medeiros A.I., Silva C.L., Malheiro A., Maffei C.M., and Faccioli L.H. Leukotrienes are involved in leukocyte recruitment induced by live Histoplasma capsulatum or by the beta-glucan present in their cell wall. Br J Pharmacol 128 (1999) 1529-1537
12. Lima K.M., Santos S.A., Lima V.M., Coelho-Castelo A.A., Rodrigues J.M.J.R., and Silva C.L. Single dose of a vaccine based on DNA encoding mycobacterial hsp65 protein plus TDM-loaded PLGA microspheres protects mice against a virulent strain of Mycobacterium tuberculosis. Gene Ther 10 (2003) 678-685
13. Eldridge J.H., Staas J.K., Meulbroek J.A., Tice T.R., and Gilley R.M. Biodegradable and biocompatible poly(dl-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies. Infect Immun 59 (1991) 2978-2986
14. Lima K.M., and Rodrigues J.R.J.M. Poly-dl-lactide-co-glycolide microspheres as a controlled release antigen delivery system. Braz J Med Biol Res 32 (1999) 171-180
15. Niwa T., Takeuchi H., Hino T., Kunou N., and Kawashima Y. Preparation of biodegradable nanospheres of water-soluble and insoluble drugs with dl-lactide/glycolide copolymer by a novel emulsification solvent diffusion method, and drug release behavior. J Contr Release 25 (1993) 89-98
16. Birnbaum T.D., Kosmala D.J., Henthorn B.D., and Peppas-Brannon L. Controlled release of 17-β-estradiol from PLGA microparticles: the effect of organic phase solvent on encapsulation and release. J Contr Release 65 (2000) 375-387
17. Bignold L.P. Measurement of chemotaxis of polymorphonuclear leukocytes in vitro. The problems of the control of gradients of chemotactic factors, of the control of the cells and of the separation of chemotaxis from chemokinesis. J Immunol Meth 108 (1988) 1-18
18. Faccioli L.H., Souza G.E., Cunha F.Q., Poole S., and Ferreira S.H. Recombinant interleukin-1 and tumor necrosis factor induce neutrophil migration "in vivo" by indirect mechanisms. Agents Actions 30 (1990) 344-349
19. Geze A., Venier-Julienne M.C., Mathieu D., Filmon R., Phan-Tan-Luu R., and Benoit J.P. Development of 5-iodo-2-deoxyuridine milling process to reduce initial burst release from PLGA microparticles. Int J Pharm 178 (1999) 257-268
20. Chen D.-B., Yang T.-Z., Lu W.-L., and Zhang Q. In vitro and in vivo study of two types of long circulating solid lipid nanoparticles containing paclitaxel. Chem Pharm Bull 49 (2001) 1444-1447
21. Bazile D.V., Ropert C., Huve P., et al. Body distribution of fully biodegradable 14C-poly(lactic acid) nanoparticles coated with albumin after parenteral administration to rats. Biomaterials 13 (1992) 1093-1102
22. Yu W., and Powell W.S. Analysis of leukotrienes, lipoxins and monooxygenated metabolites of arachidonic acid by reversed-phase high-pressure liquid chromatography. Anal Biochem 226 (1995) 241-251
23. Powell W.S., Wang L., Khanapure S.P., Manna S., and Rokach J. High-pressure liquid chromatography of oxo-eicosanoids derived from arachidonic acid. Anal Biochem 247 (1997) 17-24
24. Bureau M.F., Barbosa De Castro C., Cortese C., Bachelet M., and Boris Vargaftig B. 5-Lipoxygenase and endotoxin-induced microvascular albumin exchanges and leukocyte recruitment in guinea-pigs lungs. Eur J Pharm 324 (1997) 89-98
25. Levy B.D., Clish C.B., Schmidt B., Gronert K., and Serhan C.N. Lipid mediator class switching during acute inflammation: signals in resolution. Nat Immunol 2 (2001) 612-619