Role of membrane redox in aging-related diseases

Acta Biologica Szegediensis

Volumn 50, Issue 1-2, 2006, Pages 67-69

  Morré, Dorothy M ^a   Morré, D James ^b  

^a PURDUE UNIVERSITY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Aging; Alzheimer's disease; Cancer; ECTO NOX proteins; Neurodegenerative diseases

Indexed keywords

AMYLOID; OXIDOREDUCTASE; PRION PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUPEROXIDE;

AGING; CANCER CELL; CELL GROWTH; CELL MEMBRANE; CELL SURFACE; CONFERENCE PAPER; DEGENERATIVE DISEASE; ELECTRON TRANSPORT; ENZYME ACTIVITY; HUMAN; OXIDATION REDUCTION REACTION;

EID: 33846433677     PISSN: 1588385X     EISSN: 15884082     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (14)

1. Bruno M, Brightman AO, Lawrence J, Werderitsh D, Morré DM, Morré DJ (1992) Stimulationg of NADH oxidase activity from rat liver plasma membrane by growth factors and hormones is decreased or absent with hepatoma plasma membranes. Biochem J 284:625-628.
2. Cho NM, Chueh P-J, Kim C, Caldwell S, Morré DM, Morré DJ (2002) Monoclonal antibody to a cancer-specific and drug-responsive hydroquinone (NADH) oxidase from the sera of cancer patients. Can Immunol Immunotherapy 51:12l-129.
3. Chueh P-J, Wu L-Y, Morré DM, Morré DJ (2004) tNOX is both necessary and sufficient as a cellular target for the anticancer actions of capsaicin and the green tea catechin (-)-epigallocatechin-3-gallate. BioFactors 20:249-263.
4. deGrey ADNJ (1999) The mitochondrial free radical theory of aging. RG Landes, Austin, TX, pp. 104-110.
5. Kelker M, Kim C, Chueh P-J, Guimont R, Morré DM and Morré DJ (2001) Cancer isoforms of a tumor-associated cell surface NADH oxidase (tNOX) has properties of a prion. Biochemistry 40:7351-7354.
6. Kim C and Morré DJ (2004) Prion proteins and ECTO-NOX proteins exhibit similar oscillating redox activities. Biochem Biophys Res Commun 315:1140-1146.
7. Markert C, Morré DM, Morré DJ (2004) Human amyloid peptides Aβ1-40 and Aβ1-42 exhibit NADH oxidase activity with copper-induced oscillations and a period length of 24 min. BioFactors 20:221-235.
8. Morré DJ (1998) NADH oxidase: A multifunctional ectoprotein of the eukaryotic cell surface, In Asard H, Bérczi A, Caubergs R, eds. Plasma Membrane Redox Systems and their Role in Biological Stress and Disease, Kluwer Academic Publishers, Dordrecht, the Netherlands, pp. 121-156.
9. Morré DJ, Morré DM (2003) Cell surface NADH oxidases (ECTO-NOX proteins) with roles in cancer, cellular time-keeping, growth, aging and neurodegenerative disease. Free Radical Res 37:795-808.
10. Morré DJ, Reust T (1997) A circulating form of NADH oxidase activity responsive to the antitumor sulfonylurea N-(4-methylphenylsulfonyl-urea)-N′-(chlorophenyl)urea (LY181984) specific to sera from cancer patients. J Biomemb Bioenerg 29:281-289.
11. Morré DJ, Caldwell S, Mayorga A, Wu L-Y, Morré DM (1997) NADH oxidase activity from sera altered by capsaicin is widely distributed among cancer patients. Arch Biochem Biophys 342:224-230.
12. Morré DJ, Guo F, Morré DM (2003) An aging-related cell surface NADH oxidase (arNOX) generates superoxide and is inhibited by coenzyme Q. Mol Cell Biochem 254:101-109.
13. Morré D J, Pogue R, Morré, DM (1999) A multifunctional ubiquinol oxidase of the external cell surface and sera. BioFactors 9:179-187.
14. Morré DM, Lenaz G, Morré, DJ (2000) Surface oxidase and oxidative stress propagation in aging. J Exp Biol 203:1513-1521.