MCMC-based linkage analysis for complex traits on general pedigrees: Multipoint analysis with a two-locus model and a polygenic component

Genetic Epidemiology

Volumn 31, Issue 2, 2007, Pages 103-114

  Sung, Yun Ju ^a   Thompson, Elizabeth A ^a   Wijsman, Ellen M ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Large pedigree; Lod score; Markov chain Monte Carlo; Multilocus; Quantitative trait locus

Indexed keywords

ARTICLE; BIOLOGICAL MODEL; CORRELATION ANALYSIS; DATA ANALYSIS SOFTWARE; DNA DETERMINATION; GENE LOCATION; GENE LOCUS; GENE SEGREGATION; GENETIC LINKAGE; GENETIC MODEL; LINKAGE ANALYSIS; MARKER GENE; MARKOV CHAIN MONTE CARLO METHOD; MONTE CARLO METHOD; MULTIFACTORIAL INHERITANCE; PARAMETRIC TEST; PEDIGREE ANALYSIS; PROBABILITY; QUANTITATIVE TRAIT LOCUS; STATISTICAL MODEL; VARIANCE;

CHROMOSOME MAPPING; COMPUTER SIMULATION; FEMALE; FOUNDER EFFECT; GENETIC MARKERS; HUMANS; LIKELIHOOD FUNCTIONS; LINKAGE (GENETICS); LOD SCORE; MALE; MODELS, GENETIC; MONTE CARLO METHOD; MULTIFACTORIAL INHERITANCE; PEDIGREE; PHENOTYPE; QUANTITATIVE TRAIT LOCI; QUANTITATIVE TRAIT, HERITABLE;

EID: 33846415092     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20194     Document Type: Article

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