Key role of the NO-pathway and matrix metalloprotease-9 in high blood flow-induced remodeling of rat resistance arteries

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 27, Issue 2, 2007, Pages 317-324

  Dumont, Odile ^a   Loufrani, Laurent ^a   Henrion, Daniel ^a,b  

^a UNIVERSITÉ D'ANGERS   (France)

^b Universite d'Angers   (France)

Author keywords

Blood flow; Endothelium; Matrix metalloproteases; Microcirculation (resistance arteries); Nitric oxide; Remodeling; Shear stress

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DOXYCYCLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE B; MATRIX METALLOPROTEINASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PERINDOPRIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY DIAMETER; ARTERY RESISTANCE; ARTERY WALL; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME MECHANISM; GENE OVEREXPRESSION; HYPERTROPHY; HYPOTHESIS; IN VIVO STUDY; KNOCKOUT GENE; MALE; MESENTERIC ARTERY OCCLUSION; MICROVASCULATURE; NONHUMAN; PRIORITY JOURNAL; RAT; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; DOXYCYCLINE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HYPERTROPHY; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MESENTERIC ARTERIES; MICE; MICE, TRANSGENIC; MICROCIRCULATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PERINDOPRIL; RATS; RATS, WISTAR; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION; VASCULAR RESISTANCE; VASOCONSTRICTION;

EID: 33846404487     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000254684.80662.44     Document Type: Article

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