Lewis x antigen mediates adhesion of human breast carcinoma cells to activated endothelium. Possible involvement of the endothelial scavenger receptor C-type lectin

Breast Cancer Research and Treatment

Volumn 101, Issue 2, 2007, Pages 161-174

  Elola, María Teresa ^a   Capurro, Mariana Isabel ^b,c   Barrio, María Marcela ^d   Coombs, Peter J ^e   Taylor, Maureen E ^e   Drickamer, Kurt ^e   Mordoh, José ^a,d  

^a FUNDACIÓN INSTITUTO LELOIR   (Argentina)

^b SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d FUCA   (Argentina)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

1, MCF; 2.15 and MCS; 7, PMN, Scavenger receptor C; Lewis x (CD15), Monoclonal antibodies FC; Type lectin

Indexed keywords

FC 2.15 MONOCLONAL ANTIBODY; LECTIN; MCS 1 MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY; STAGE SPECIFIC EMBRYO ANTIGEN 1; UNCLASSIFIED DRUG;

ARTICLE; BLOTTING; BREAST CARCINOMA; CANCER CELL; CANCER THERAPY; CELL ADHESION; CELL AGGREGATION; CELL INTERACTION; CONTROLLED STUDY; CYTOLYSIS; ENDOTHELIUM; ENDOTHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION;

ANTIBODIES, MONOCLONAL; ANTIGENS, CD15; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; LECTINS, C-TYPE; NEUTROPHILS;

EID: 33846330127     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-006-9286-9     Document Type: Article

References (45)

1. Gooi HC, Feizi T, Kapadia A, Knowles BB, Solter D, Evans MJ (1981) Stage-specific embryonic antigen involves α1 → 3 fucosylated type 2 blood group chains. Nature 292:156-158
2. Hakomori S, Nudelman E, Levery S, Solter D, Knowles BB (1981) The hapten structure of a developmentally regulated glycolipid antigen (SSEA-1) isolated from human erytrocytes and adenocarcinoma: a preliminary note. Biochem Biophys Res Commun 100:1578-1586
3. Spooncer E, Fukuda M, Klock JC, Oates JE, Dell A (1984) Isolation and characterization of polyfucosylated lactosaminoglycan from human granulocytes. J Biol Chem 259:4792-4801
4. Mordoh J, Leis S, Bravo AI, Podhajcer OL, Ballaré C, Capurro M, Kairiyama C, Bover L (1994) Description of a new monoclonal antibody, FC-2.15, reactive with human breast cancer and other human neoplasia. Int J Biological Markers 9:125-134
5. Hittelet A, Camby I, Nagy N, Legendre H, Bronckart Y, Decaestecker C, Kaltner H, Nifant'ev NE, Bovin NV, Pector JC, Salmon I, Gabius HJ, Kiss R, Yeaton P (2003) Binding sites for Lewis antigens are expressed by human colon cancer cells and negatively affect their migration. Lab Invest 83:777-787
6. Ohana-Malka O, Benharroch D, Isakov N, Prinsloo I, Shubinsky G, Sacks M, Gopas J (2003) Selectins and anti-CD15 (Lewis x/a) antibodies transmit activation signals in Hodgkin's lymphoma-derived cell lines. Exp Hematol 31:1057-1065
7. Rizzatti EG, Portieres FL, Martins SL, Rego EM, Zago MA, Falcao RP (2004) Microgranular and t(11;17)/PLZF-RARalpha variants of acute promyelocytic leukemia also present the flow cytometric pattern of CD13, CD34 and CD15 expression characteristic of PML-RARalpha gene rearrangement. Am J Hematol 76:44-51
8. Johnston DS, Wright WW, Shaper JH, Hokke CH, Van den Eijnden DH, Joziasse DH (1998) Murine sperm-zona binding, a fucosyl residue is required for a high affinity sperm-binding ligand. A second site on sperm binds a nonfucosylated, beta-galactosyl-capped oligosaccharide. J Biol Chem 273:1888-1895
9. D'Costa S, Petitte J-N (1999) Characterization of stage-specific embryonic antigen-1 (SSEA-1) expression during early development of the turkey embryo. Int J Dev Biol 43:349-356
10. Allendoerfer KL, Durairaj A, Matthews GA, Patterson PH (1999) Morphological domains of Lewis X-FORSE 1 immunolabeling in the embryonic neural tube are due to developmental regulation of cell surface carbohydrate expression. Dev Biol 211:208-219
11. Geijtenbeek TB, Van Vliet SJ, Engering A, Ba TH, Van Kooyk Y (2004) Self- and non-self-recognition by C-type lectins on dendritic cells. Annu Rev Immunol 22:33-54
12. van Gisbergen KP, Aarnoudse CA, Meijer GA, Geijtenbeek TB, van Kooyk Y (2005) Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin. Cancer Res 65:5935-5944
13. Kannagi R, Isawa M, Koike T, Miyazaki K, Kimura N (2004) Carbohydrate-mediated cell adhesion in cancer metastasis and angiogenesis. Cancer Sci 95:377-384
14. Vestweber D, Blanks JE (1999) Mechanisms that regulate the function of the selectins and their ligands. Physiol Rev 79:181-213
15. Giavazzi R, Foppolo M, Dossi R, Remuzzi A (1993) Rolling and adhesion of human tumor cells on vascular endothelium under physiologicalflowconditions. J Clin Invest 92:3038-3044
16. Kitayama J, Tsuno N, Sunami E, Osada T, Muto T, Nagawa H (2000) E-selectin can mediate the arrest type of adhesion of colon cancer cells under physiological shear flow. Eur J Cancer 36:121-127
17. Burdick MM, McCaffery JM, Kim YS, Bochner BS, Konstantopoulos K (2003) Colon carcinoma cell glycolipids, integrins, and other glycoproteins mediate adhesion to HUVECs under flow. Am J Physiol Cell Physiol 284:C977-C987
18. Mitoma J, Petryniak B, Hiraoka N, Yeh J-C, Lowe JB, Fukuda M (2003) Extended core 1 and core 2 branched Oglycans differentially modulate sialyl Lewis x-type L-selectin ligand activity. J Biol Chem 278:9953-9961
19. Skubitz KM, Snook RW (1987) Monoclonal antibodies that recognize lacto-N-fucopentaose III (CD15) react with the adhesion-promoting glycoprotein family (LFA-1/Hmac-1/gp150,95) and CR1 on human neutrophils. J Immunol 139:1631-1639
20. Skubitz KM, Mendiola JR, Collett MS (1988) CD15 monoclonal antibodies with a phosphotyrosine-containing protein on the surface of human neutrophils. J Immunol 141:4318-4323
21. Albrechtsen M, Kerr MA (1989) Characterization of human neutrophil glycoproteins expressing the CD15 differentiation antigen (3-fucosyl-N- acetyllactosamine). British J Haematol 72:312-320
22. Lucka L, Fernando M, Grunow D, Kannicht C, Horst AK, Nollau P, Wagener C (2005) Identification of Lewis x structures of the cell adhesion molecule CEACAM1 from human granulocytes. Glycobiology 15:87-100
23. x trisaccharide and related glycan ligands. J Biol Chem 280:22993-22999
24. Ballaré C, Barrio M, Portela P, Mordoh J (1995) Functional properties of FC-2.15, a monoclonal antibody that mediates human complement cytotoxicity against breast cancer cells. Cancer Immunol Immunother 41:15-22
25. Capurro M, Bover L, Portela P, Livingston P, Mordoh J (1998) FC-2.15, a monoclonal antibody active against human breast cancer, specifically recognizes Lewis X hapten. Cancer Immunol Immunother 45:334-339
26. Mordoh J, Silva C, Albarellos M, Bravo AI, Kairiyama C (1995) Phase I clinical trial in cancer patients of a new monoclonal antibody FC-2.15 reacting with tumor proliferating cells. J Immunother 17:151-160
27. X monoclonal antibody FC-2.15 on human polymorphonuclear neutrophils and MCF-7 breast tumor cells. In vitro and in vivo study. Cancer Immunol Immunother 48:100-108
28. Robinson MK, Andrew D, Rosen H, Brown D, Stephens P, Butcher EC (1992) Antibody against the Leu-CAM betachain (CD18) promotes both LFA-1- and CR3-dependent adhesion events. J Immunol 148:1080-1085
29. Sánchez-Madrid F, Krensky AM, Ware CF, Robbins E, Strominger JL, Burakoff SJ, Springer TA (1982) Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2 and LFA-3. Proc Natl Acad Sci USA 79:7489-7493
30. Drbal K, Angelisová P, Cerný J, Pavlistova D, Cebecauer M, Novak P, Horejsi V (2000) Human leukocytes contain a large pool of free forms of CD18. Biochem Biophys Res Commun 275:295-299
31. Jaffé EA, Nachman RL, Becker CG, Minick CR (1973) Culture of human endothelial cells derived from umbilical veins: identification by morphologic and immunologic criteria. J Clin Invest 52:2745-2756
32. Soule HD, Vazguez J, Long A, Albert S, Brennan M (1973) A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 51:1409-1416
33. Kawamura N, Imanishi N, Koike H, Nakahara H, Phillips L, Morooka S (1995) Lipoteichoic acid-induced neutrophil adhesion via E-selectin to human umbilical vein endothelial cells (HUVECs). Biochem Biophys Res Commun 217:1208-1215
34. 12 myoblast cell line and the roles of calcium ion and oxidative stress on the toxic effects. Toxicology 219:73-84
35. Majuri M-L, Pinola M, Niemelä R, Tiisala S, Natunen J, Renkonen O, Renkonen R (1994) α2,3-Sialyl and α1,3-fucosyltransferase-dependent synthesis of sialyl Lewis x, an essential oligosaccharide present on L-selectin counterreceptors, in culture endothelial cells. Eur J Immunol 24:3205-3210
36. x. Science 250:1130-1132
37. Buyon JP, Abramson SB, Philips MR, Slade SG, Ross GD, Weissman G, Winchester RJ (1988) Dissociation between increased surface expression of gp165/95 and homotypic neutrophil aggregation. J Immunol 140:3156-3160
38. Bild T, Jose J, Hartmann RW (2004) Discovery of inhibitors of MCF-7 tumor cell adhesion to endothelial cells and investigation on their mode of action. Archiv der Pharmazie 337:687-694
39. Harris JF, Chin J, Jewett MA, Kennedy M, Gorczynski RM (1984) Monoclonal antibodies against SSEA-1 antigen: binding properties and inhibition of human natural killer cell activity against target cells bearing SSEA-1 antigen. J Immunol 132:2502-2509
40. Magnani JL, Ball ED, Fanger MW, Hakomori S-I, Ginsburg V (1984) Monoclonal antibodies PMN 6, PMN 29, and PM-81 bind differently to glycolipids containing a sugar sequence ocurring in lacto-N-fucopentaose III. Arch Biochem Biophys 233:501-506
41. van Roon AM, Pannu NS, de Vrind JP, van der Marel GA, van Boom JH, Hokke CH, Deelder AM, Abrahams JP (2004) Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen. Structure 7:1227-1236
42. Ball ED, Selvaggi K, Hurd D, Herzig R, Clark L, Malley V, Persichetti J, deMagelhaus-Silverman M (1995) Phase I clinical trial of serotherapy in patients with acute myeloid leukemia with an immunoglobulin M monoclonal antibody to CD15. Clin Cancer Res 1:965-972
43. x) and CD15-expressing carcinoembryonic antigen-related glycoprotein NCA-160. Biochem J 288:23-27
44. Wong IHN, Lau WY, Leung T, Yeo W, Johnson PJ (1999) Hematogenous dissemination of hepatocytes and tumor cells after surgical resection of hepatocellular carcinoma: a quantitative analysis. Clin Can Res 5:4021-4027
45. Yamashita JI, Kurusu Y, Fujino N, Saisyoji T, Ogawa M (2000) Detection of circulating tumor cells in patients with non-small cell lung cancer undergoing lobectomy by video-assisted thoracic surgery: a potential hazard for intraoperative hematogenous tumor cell dissemination. J Thorac Cardiovasc Surg 119:899-905