메뉴 건너뛰기




Volumn 64, Issue 4, 2006, Pages 941-945

Alzheimer's disease in Brazilian elderly has a relation with homocysteine but not with MTHFR polymorphisms

Author keywords

Alzheimer's disease; Homocysteine; MTHFR

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; PYRIDOXINE;

EID: 33846310455     PISSN: 0004282X     EISSN: 16784227     Source Type: Journal    
DOI: 10.1590/S0004-282X2006000600010     Document Type: Article
Times cited : (34)

References (33)
  • 1
    • 0028487161 scopus 로고
    • Human methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification
    • Goyette P, Sumner JS, Milos R, et al. Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification. Nat Gen 1994;7:195-200.
    • (1994) Nat Gen , vol.7 , pp. 195-200
    • Goyette, P.1    Sumner, J.S.2    Milos, R.3
  • 2
    • 0031971515 scopus 로고    scopus 로고
    • A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
    • Van der Put NMJ, Gabreels F, Stevens EMB, et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 1998;62:1044-1051.
    • (1998) Am J Hum Genet , vol.62 , pp. 1044-1051
    • Van der Put, N.M.J.1    Gabreels, F.2    Stevens, E.M.B.3
  • 3
    • 0023696435 scopus 로고
    • Intermediate homocysteinemia: A thermolabile variant of methylenetetrahydrofolate reductase
    • Kang SS, Zhou J, Wong PWK, et al. Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. Am J Hum Genet 1988;43:414-421.
    • (1988) Am J Hum Genet , vol.43 , pp. 414-421
    • Kang, S.S.1    Zhou, J.2    Wong, P.W.K.3
  • 4
    • 0037316039 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease
    • Andreassi MG, Botto N, Battaglia FCD, et al. Methylenetetrahydrofolate reductase gene C677T polymorphism, homocysteine, vitamin B12, and DNA damage in coronary artery disease. Hum Genet 2003;112:171-177.
    • (2003) Hum Genet , vol.112 , pp. 171-177
    • Andreassi, M.G.1    Botto, N.2    Battaglia, F.C.D.3
  • 5
    • 0033954991 scopus 로고    scopus 로고
    • Oxidative stress and Alzheimer disease
    • Christen Y. Oxidative stress and Alzheimer disease. Am J Clin Nutr 2000;71(Suppl):S621-S629.
    • (2000) Am J Clin Nutr , vol.71 , Issue.SUPPL.
    • Christen, Y.1
  • 6
    • 0027420369 scopus 로고
    • Tau protein and the neurofibrillary pathology of Alzheimer's disease
    • Goedert M. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Trends Neurosci 1993;76:460-465.
    • (1993) Trends Neurosci , vol.76 , pp. 460-465
    • Goedert, M.1
  • 7
    • 0026488226 scopus 로고
    • Cytoskeletal abnormalities in Alzheimer's disease
    • Lovestone S, Anderton B. Cytoskeletal abnormalities in Alzheimer's disease. Curr Opin Neurol Neurosurg 1992;5:883-888.
    • (1992) Curr Opin Neurol Neurosurg , vol.5 , pp. 883-888
    • Lovestone, S.1    Anderton, B.2
  • 8
    • 0023105114 scopus 로고
    • The precursor of Alzheimer's disease: Amyloid A4 protein resembles a cell-surface receptor
    • Kang J, Lemaire HG, Unterbeck A, et al. The precursor of Alzheimer's disease: amyloid A4 protein resembles a cell-surface receptor. Nature 1987;325:733-736.
    • (1987) Nature , vol.325 , pp. 733-736
    • Kang, J.1    Lemaire, H.G.2    Unterbeck, A.3
  • 9
    • 0031597388 scopus 로고    scopus 로고
    • Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease
    • Clarke R, Smith AD, Phil D, et al. Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998;55:1449-1455.
    • (1998) Arch Neurol , vol.55 , pp. 1449-1455
    • Clarke, R.1    Smith, A.D.2    Phil, D.3
  • 10
    • 0038653351 scopus 로고    scopus 로고
    • Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment
    • Religa D, Stycz M, Peplonska B, et al. Homocysteine, apolipoproteine E and methylenetetrahydrofolate reductase in Alzheimer's disease and mild cognitive impairment. Dement Geriatr Cogn Disord 2003;16:64-70.
    • (2003) Dement Geriatr Cogn Disord , vol.16 , pp. 64-70
    • Religa, D.1    Stycz, M.2    Peplonska, B.3
  • 11
    • 0038446637 scopus 로고    scopus 로고
    • Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults
    • Kluijtmans LA, Young IS, Boreham CA, et al. Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults. Blood 2003;101:2483-2488.
    • (2003) Blood , vol.101 , pp. 2483-2488
    • Kluijtmans, L.A.1    Young, I.S.2    Boreham, C.A.3
  • 12
    • 11144354439 scopus 로고    scopus 로고
    • Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease
    • Anello G, Gueant-Rodriguez RM, Bosco P, et al. Homocysteine and methylenetetrahydrofolate reductase polymorphism in Alzheimer's disease. Neuroreport 2004;15:859-861.
    • (2004) Neuroreport , vol.15 , pp. 859-861
    • Anello, G.1    Gueant-Rodriguez, R.M.2    Bosco, P.3
  • 13
    • 33846269899 scopus 로고    scopus 로고
    • Folate deprivation induces neurodegeneration: Roles of oxidative stress and increased homocysteine
    • Ho PI, Ashline D, Dhitavat S, et al. Folate deprivation induces neurodegeneration: roles of oxidative stress and increased homocysteine. Am J Clin Nutr 2003;61:560-565.
    • (2003) Am J Clin Nutr , vol.61 , pp. 560-565
    • Ho, P.I.1    Ashline, D.2    Dhitavat, S.3
  • 14
    • 0035056015 scopus 로고    scopus 로고
    • Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia
    • Zuliani G, Ble A, Zanca R, et al. Genetic polymorphisms in older subjects with vascular or Alzheimer's dementia. Acta Neurol Scand 2001;103:304-308.
    • (2001) Acta Neurol Scand , vol.103 , pp. 304-308
    • Zuliani, G.1    Ble, A.2    Zanca, R.3
  • 15
    • 0035940757 scopus 로고    scopus 로고
    • The C677T methylenetetrahydrofolate reductase mutation is not associated with Alzheimer's disease
    • Brunelli T, Bagnoli S, Giusti B. The C677T methylenetetrahydrofolate reductase mutation is not associated with Alzheimer's disease. Neurosci Lett 2001;315:103-105.
    • (2001) Neurosci Lett , vol.315 , pp. 103-105
    • Brunelli, T.1    Bagnoli, S.2    Giusti, B.3
  • 16
    • 0036453105 scopus 로고    scopus 로고
    • Genetic analysis of vascular factors in Alzheimer's disease
    • Wakutani Y, Kowa H, Kusumi M, et al. Genetic analysis of vascular factors in Alzheimer's disease. Ann NY Acad Sci 2002;977:232-238.
    • (2002) Ann NY Acad Sci , vol.977 , pp. 232-238
    • Wakutani, Y.1    Kowa, H.2    Kusumi, M.3
  • 17
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
    • McKahann G, Drachmann D, Folstein M. Clinical diagnosis of Alzheimer disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease. Neurology 1984;34:939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKahann, G.1    Drachmann, D.2    Folstein, M.3
  • 18
    • 0032992889 scopus 로고    scopus 로고
    • Rapid and accurate HPLC assay dos pIAM total homocysteine and cysteine in a clinical laboratorysetting
    • Pfiffer CM, Huff DL, Gunter EW. Rapid and accurate HPLC assay dos pIAM total homocysteine and cysteine in a clinical laboratorysetting. Clin Chem 1999;454:290-292.
    • (1999) Clin Chem , vol.454 , pp. 290-292
    • Pfiffer, C.M.1    Huff, D.L.2    Gunter, E.W.3
  • 19
    • 0007505841 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation at the methylenetetrahydro folate reductase locus
    • Frosst P, Pai A, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation at the methylenetetrahydro folate reductase locus. Nat Gen 1995; 10:110-113.
    • (1995) Nat Gen , vol.10 , pp. 110-113
    • Frosst, P.1    Pai, A.2    Milos, R.3
  • 20
    • 0033607241 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults
    • Skibola CF, Smith MY, Kane E, et al. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Rev PNAS 1999;96:12810-12815.
    • (1999) Rev PNAS , vol.96 , pp. 12810-12815
    • Skibola, C.F.1    Smith, M.Y.2    Kane, E.3
  • 21
    • 0030670874 scopus 로고    scopus 로고
    • Neuropathological assessment of the lesion of significance in vascular dementia
    • Esiri MM, Wilcock GK, Morris JH. Neuropathological assessment of the lesion of significance in vascular dementia. J Neurol Neurosurg Psychiatry 1997;63:749-753.
    • (1997) J Neurol Neurosurg Psychiatry , vol.63 , pp. 749-753
    • Esiri, M.M.1    Wilcock, G.K.2    Morris, J.H.3
  • 22
    • 0026443092 scopus 로고
    • Plasma homocysteine in nonvascular dementia of depressed elderly people
    • Bell IR, Edman JS, Selhub J, et al. Plasma homocysteine in nonvascular dementia of depressed elderly people. Acta Psychiatr Scand 1992;86:386-390.
    • (1992) Acta Psychiatr Scand , vol.86 , pp. 386-390
    • Bell, I.R.1    Edman, J.S.2    Selhub, J.3
  • 23
    • 0035050096 scopus 로고    scopus 로고
    • Hyperhomocysteinemia associated with poor recallin the third National Health and Nutrition Examination Survey
    • Morris MS, Jacques PF, Rosenberg IH, et al. Hyperhomocysteinemia associated with poor recallin the third National Health and Nutrition Examination Survey. Am J Clin Nutr 2001;73:927-933.
    • (2001) Am J Clin Nutr , vol.73 , pp. 927-933
    • Morris, M.S.1    Jacques, P.F.2    Rosenberg, I.H.3
  • 24
    • 0037075257 scopus 로고    scopus 로고
    • Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
    • Seshadri S, Beiser, A, Selhub J, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002;346:476-483.
    • (2002) N Engl J Med , vol.346 , pp. 476-483
    • Seshadri, S.1    Beiser, A.2    Selhub, J.3
  • 25
    • 0035205173 scopus 로고    scopus 로고
    • Plasma folate, vitamin B12 and total homocysteine and homozygosity for the C677T mutation of the 5,10-methylenetetrahydrofolate reductase gene in patients with Alzheimer's dementia
    • Postiglione A, Milan G, Ruocco A, et al. Plasma folate, vitamin B12 and total homocysteine and homozygosity for the C677T mutation of the 5,10-methylenetetrahydrofolate reductase gene in patients with Alzheimer's dementia. Gerontology 2001;47:324-329.
    • (2001) Gerontology , vol.47 , pp. 324-329
    • Postiglione, A.1    Milan, G.2    Ruocco, A.3
  • 26
    • 0026533906 scopus 로고
    • The pathogenesis of homocysteinemia: Interru ption of the coordinate regulation by S-adenosylmethionine of the remethylation and transulfuration of homocysteine
    • Selhub JL, Mlller JW The pathogenesis of homocysteinemia: interru ption of the coordinate regulation by S-adenosylmethionine of the remethylation and transulfuration of homocysteine. Am J Clin Nutr 1991;55:131-138.
    • (1991) Am J Clin Nutr , vol.55 , pp. 131-138
    • Selhub, J.L.1    Mlller, J.W.2
  • 27
    • 0035412398 scopus 로고    scopus 로고
    • Pharmacogenetics of methothrexate: Toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism
    • Ulrich CM, Yasui Y, Storb R, et al. Pharmacogenetics of methothrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism. Blood 2001;98:231-234.
    • (2001) Blood , vol.98 , pp. 231-234
    • Ulrich, C.M.1    Yasui, Y.2    Storb, R.3
  • 28
    • 0031963298 scopus 로고    scopus 로고
    • Relation of three genetic traits to venous thrombosis in an African-American population
    • Dilley A, Austin H, Hooper WC, et al. Relation of three genetic traits to venous thrombosis in an African-American population. Am J Epidemiol 1998;147:30-35.
    • (1998) Am J Epidemiol , vol.147 , pp. 30-35
    • Dilley, A.1    Austin, H.2    Hooper, W.C.3
  • 29
    • 0032231408 scopus 로고    scopus 로고
    • Heterogeneity in world distribution of the thermolabile C677T mutation in 5-10-methylenetetrahydrofolate reductase
    • Pepe G, Venegas CO, Giusti B, et al. Heterogeneity in world distribution of the thermolabile C677T mutation in 5-10-methylenetetrahydrofolate reductase. Am J Hum Genet 1998;63:917-920.
    • (1998) Am J Hum Genet , vol.63 , pp. 917-920
    • Pepe, G.1    Venegas, C.O.2    Giusti, B.3
  • 30
    • 33846286007 scopus 로고    scopus 로고
    • Fernandez LL, Scheibe RM. Is MTHFR polymorphism a risk factor for Alzhimer's disease like APOE ? Arq Neuropsiquiatr 2005;63:1-6.
    • Fernandez LL, Scheibe RM. Is MTHFR polymorphism a risk factor for Alzhimer's disease like APOE ? Arq Neuropsiquiatr 2005;63:1-6.
  • 31
    • 0034971263 scopus 로고    scopus 로고
    • Lack of replication of association finings in complex disease: An analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease
    • Prince JA, Feuk L, Gottfries J, et al. Lack of replication of association finings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease. Eur J Hum Genet 2001;9:437-444.
    • (2001) Eur J Hum Genet , vol.9 , pp. 437-444
    • Prince, J.A.1    Feuk, L.2    Gottfries, J.3
  • 32
    • 0030942430 scopus 로고    scopus 로고
    • Analysis of alpha-1 antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolate reductase loci as candidates for dementia
    • Tysoe C, Galinsky D, Robinson D, et al. Analysis of alpha-1 antichymotrypsin, presenilin-1, angiotensin-converting enzyme, and methylenetetrahydrofolate reductase loci as candidates for dementia. Am J Med Genet 1997;74:207-212.
    • (1997) Am J Med Genet , vol.74 , pp. 207-212
    • Tysoe, C.1    Galinsky, D.2    Robinson, D.3
  • 33
    • 0030826587 scopus 로고    scopus 로고
    • Thermolabile methylenetetrahydrofolate reductase in coronary artery disease
    • Kluijtmans LA, Kastelein JJ, Lindemans J, et al. Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Circulation 1997;96:2573-2577.
    • (1997) Circulation , vol.96 , pp. 2573-2577
    • Kluijtmans, L.A.1    Kastelein, J.J.2    Lindemans, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.