Role of endogenous hydrogen peroxide in the development of nitrate tolerance

Vascular Pharmacology

Volumn 46, Issue 4, 2007, Pages 247-252

  Ghatta, Srinivas ^a   Hemmer, Ross B ^a   Uppala, Saritha ^a   O'Rourke, Stephen T ^a  

^a NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

Hydrogen peroxide; Nitrate tolerance; Nitroglycerin; Rat aorta; Superoxide

Indexed keywords

CATALASE; EBSELEN; GLUTATHIONE PEROXIDASE; GLYCERYL TRINITRATE; HYDROGEN PEROXIDE; NITRATE; NORADRENALIN; SUPEROXIDE DISMUTASE; TEMPOL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG TOLERANCE; FLUOROMETRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; VASCULAR RING;

ANIMALS; ANTIOXIDANTS; AORTA, THORACIC; AZOLES; CATALASE; CYCLIC N-OXIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROGEN PEROXIDE; MALE; NITROGLYCERIN; ORGANOSELENIUM COMPOUNDS; RATS; RATS, SPRAGUE-DAWLEY; SPIN LABELS; TACHYPHYLAXIS; TIME FACTORS; VASODILATION; VASODILATOR AGENTS;

EID: 33846280899     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2006.10.007     Document Type: Article

References (23)

1. Abou-Mohamed G., Johnson J.A., Jin L., El-Remessy A.B., Do K., Kaesemeyer W.H., Caldwell R.B., and Caldwell R.W. Roles of superoxide, peroxynitrite, and protein kinase C in the development of tolerance to nitroglycerin. J. Pharmacol. Exp. Ther. 308 (2004) 289-299
2. Bassenge E., Fink N., Skatchkov M., and Fink B. Dietary supplement with vitamin C prevents nitrate tolerance. J. Clin. Invest. 102 (1998) 67-71
3. Chen Z., Foster M.W., Zhang J., Mao L., Rockman H.A., Kawamoto T., Kitagawa K., Nakayama K.I., Hess D.T., and Stamler J.S. An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 12159-12164
4. Chung S.J., and Fung H.L. Identification of the subcellular site for nitroglycerin metabolism to nitric oxide in bovine coronary smooth muscle cells. J. Pharmacol. Exp. Ther. 253 (1990) 614-619
5. Daiber A., Oelze M., Sulyok S., Coldewey M., Schulz E., Treiber N., Hink U., Mulsch A., Scharffetter-Kochanek K., and Munzel T. Heterozygous deficiency of manganese superoxide dismutase in mice (Mn-SOD+/-): a novel approach to assess the role of oxidative stress for the development of nitrate tolerance. Mol. Pharmacol. 68 (2005) 579-588
6. Daniel T.A., and Nawarskas J.J. Vitamin C in the prevention of nitrate tolerance. Ann. Pharmacother. 34 (2000) 1193-1197
7. de la Lande I.S., Stepien J.M., Philpott A.C., Hughes P.A., Stafford I., and Horowitz J.D. Aldehyde dehydrogenase, nitric oxide synthase and superoxide in ex vivo nitrate tolerance in rat aorta. Eur. J. Pharmacol. 496 (2004) 141-149
8. Ellis G.R., Anderson R.A., Chirkov Y.Y., Morris-Thurgood J., Jackson S.K., Lewis M.J., Horowitz J.D., and Frenneaux M.P. Acute effects of vitamin C on platelet responsiveness to nitric oxide donors and endothelial function in patients with chronic heart failure. J. Cardiovasc. Pharmacol. 37 (2001) 564-570
9. Faraci F.M., and Didion S.P. Vascular protection: superoxide dismutase isoforms in the vessel wall. Arterioscler. Thromb. Vasc. Biol. 24 (2004) 1367-1373
10. Fung H.L. Biochemical mechanism of nitroglycerin action and tolerance: is this old mystery solved?. Annu. Rev. Pharmacol. Toxicol. 44 (2004) 67-85
11. Ghatta S., and O'Rourke S.T. Nitroglycerin-induced release of calcitonin gene-related peptide from sensory nerves attenuates the development of nitrate tolerance. J. Cardiovasc. Pharmacol. 47 (2006) 174-180
12. 2 in rat aorta. Vascul. Pharmacol. 43 (2005) 128-138
13. Hink U., Oelze M., Kolb P., Bachschmid M., Zou M.H., Daiber A., Mollnau H., August M., Baldus S., Tsilimingas N., Walter U., Ullrich V., and Munzel T. Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance. J. Am. Coll. Cardiol. 42 (2003) 1826-1834
14. Matoba T., Shimokawa H., Kubota H., Morikawa K., Fujiki T., Kunihiro I., Mukai Y., Hirakawa Y., and Takeshita A. Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries. Biochem. Biophys. Res. Commun. 290 (2002) 909-913
15. McDonald B.J., and Bennett B.M. Cytochrome P-450 mediated biotransformation of organic nitrates. Can. J. Physiol. Pharm. 68 (1990) 1552-1557
16. Munzel T., Sayegh H., Freeman B.A., Tarpey M.M., and Harrison D.G. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. J. Clin. Invest. 95 (1995) 187-194
17. Munzel T., Hink U., Yigit H., Macharzina R., Harrison D.G., and Mulsch A. Role of superoxide dismutase in in vivo and in vitro nitrate tolerance. Br. J. Pharmacol. 127 (1999) 1224-1230
18. Munzel T., Mollnau H., Hartmann M., Geiger C., Oelze M., Warnholtz A., Yehia A.H., Forstermann U., and Meinertz T. Effects of a nitrate-free interval on tolerance, vasoconstrictor sensitivity and vascular superoxide production. J. Am. Coll. Cardiol. 36 (2000) 628-634
19. Munzel T., Daiber A., and Mulsch A. Explaining the phenomenon of nitrate tolerance. Circ. Res. 97 (2005) 618-628
20. O'Rourke S.T., Hammad H., Delagrange P., Scalbert E., and Vanhoutte P.M. Melatonin inhibits nitrate tolerance in isolated coronary arteries. Br. J. Pharmacol. 139 (2003) 1326-1332
21. Parker J.D., and Parker J.O. Nitrate therapy for stable angina pectoris. N. Engl. J. Med. 338 (1998) 520-531
22. Uddin M., Yang H., Shi M., Polley-Mandal M., and Guo Z. Elevation of oxidative stress in the aorta of genetically hypertensive mice. Mech. Ageing Dev. 124 (2003) 811-817
23. Yada T., Shimokawa H., Hiramatsu O., Kajita T., Shigeto F., Goto M., Ogasawara Y., and Kajiya F. Hydrogen peroxide, an endogenous endothelium-derived hyperpolarizing factor, plays an important role in coronary autoregulation in vivo. Circulation 107 (2003) 1040-1045