Determination and pharmacokinetic study of syringin and chlorogenic acid in rat plasma after administration of Aidi lyophilizer

Biomedical Chromatography

Volumn 20, Issue 12, 2006, Pages 1315-1320

  Li, Qing ^a   Sun, Li Xin ^a   Jia, Ying ^a,b   Wang, Zhi Wei ^a   Shen, Zhen Duo ^a   Bi, Kai Shun ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b INNER MONGOLIA UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

Aidi lyophilizer; Chloregenic acid; High performance liquid chromatography; Pharmacokinetic study; Syringin; Wavelength transfer technology

Indexed keywords

BODY FLUIDS; PARTICLE SIZE; PARTICLE SIZE ANALYSIS; PHARMACOKINETICS; RATS;

AIDI LYOPHILIZER; CHLOREGENIC ACID; CHLOROGENIC ACIDS; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC METHODS; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; PHARMACOKINETIC STUDIES; RAT PLASMA; SYRINGIN; TRANSFER TECHNOLOGIES; WAVELENGTH-TRANSFER TECHNOLOGY;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ACETONITRILE; AIDI LYOPHILIZER; CHINESE DRUG; CHLOROGENIC ACID; PHOSPHORIC ACID; SYRINGIN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CALIBRATION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STRUCTURE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; RAT; RELIABILITY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STRUCTURE ANALYSIS; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION PROCESS;

RATTUS;

EID: 33846250303     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.698     Document Type: Article

References (13)

1. Bandyopadhyay G, Biswas T, Roy KC, Mandal S, Mandal C, Pal BC, Bhattacharya S, Rakshit S, Bhattacharya DK, Chaudhuri U, Konar A and Bandyopadhyay S. Chlorogenic acid inhibits Bcr-Abl tyrosine kinase and triggers p38 mitogen-activated protein kinase-dependent apoptosis in chronic myelogenous leukemic cells. Blood 2004;104:2514-2522.
2. Cho JY, Nam KH, Kim AR, Park J, Yoo ES, Baik KU, Yu YH and Park MH. In-vitro and in-vivo immunomodulatory effects of syringin. Journal of Pharmacy and Pharmacology 2001; 53:1287-1294.
3. Choi J, Shin KM, Park HJ, Jung HJ, Kim HJ, Lee YS, Rew JH and Lee KT. Anti-inflammatory and antinociceptive effects of sinapyl alcohol and its glucoside syringin. Planta Medica 2004; 70: 1027-1032.
4. Duan YL, Fan XH and Hou JQ. Clinical observation on effect of Aidi injection in treating radiation injury of lung. Zhongguo Zhong Xi Yi Jie He Za Zhi 2004; 24: 256-257.
5. Feng R, Lu Y, Bowman LL, Qian Y, Castranova V and Ding M. Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid. Journal of Biological Chemistry 2005; 280: 27888-27895.
6. Li XP, Yu J, Luo JY, Li HS, Han FJ, Chen XG and Hu ZD. Determination and pharmacokinetic study of chlorogenic acid in rat dosed with Yin-Huang granules by RP-HPLC. Biomedical Chromatography 2006; 20: 206-210.
7. Liao Q-F, Jia J, Gao Q-T, Chen X-H, Tan X-J and Bi K-S. High-performance liquid chromatographic method for determination and pharmacokinetic study of chlorogenic acid in the plasma of rats after administration of the Chinese medicinal preparation luying decoction. Chromatographia 2005; 62: 103-107.
8. Min BS, Na MK, Oh SR, Ahn KS, Jeong GS, Li G, Lee SK, Joung H and Lee HK. New furofuran and butyrolactone lignans with antioxidant activity from the stem bark of Styrax japonica. Journal of Natural Products 2004; 67: 1980-1984.
9. Petzke KJ, Schuppe S, Rohn S, Rawel HM and Kroll J. Chlorogenic acid moderately decreases the quality of whey proteins in rats. Journal of Agriculture and Food Chemistry 2005; 53: 3714-3720.
10. Pyo MK, Lee Y and Yun-Choi HS. Anti-platelet effect of the constituents isolated from the barks and fruits of Magnolia obovata. Archives of Pharmacal Research 2002; 25: 325-328.
11. Shinomiya K, Omichi J, Ohnishi R, Ito H, Yoshida T and Kamei C. Effects of chlorogenic acid and its metabolites on the sleep-wakefulness cycle in rats. European Journal of Pharmacology 2004; 504: 185-189.
12. Xu K, Luo HY and Li LN. Clinical study on comprehensive treatment of primary liver cancer mainly with chinese medicinal perfusion/ embolization. Zhongguo Zhong Xi Yi Jie He Za Zhi 2005; 25: 299-302.
13. Yang H, Yuan B, Li L, Chen H and Li F. HPLC determination and pharmacokinetics; of chlorogenic acid in rabbit plasma after an oral dose of Flos Lonicerae extract. Journal of Chromatographic Science 2004; 42: 173-176.