HPLC Determination and Pharmacokinetics of Chlorogenic Acid in Rabbit Plasma after An Oral Dose of Flos Lonicerae Extract

Journal of Chromatographic Science

Volumn 42, Issue 4, 2004, Pages 173-176

  Yang, Hongjuan ^a   Yuan, Bo ^a   Li, Lei ^a   Chen, Huashan ^a   Li, Famei ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONITRILE; CHLOROGENIC ACID; FLOS LONICERAE EXTRACT; METHANOL; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PLASMA; QUANTITATIVE ANALYSIS; RABBIT; REVERSED PHASE LIQUID CHROMATOGRAPHY; STANDARD; ULTRAVIOLET RADIATION;

ANIMALIA; FLOS; ORYCTOLAGUS CUNICULUS;

EID: 1842852950     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chromsci/42.4.173     Document Type: Article

References (10)

1. Y. Shi, R.B. Shi, and Y.R. Lu. Advance in research of botanical resources, chemical ingredients and pharmacological effects for Lonicera japonica. J. Chin. Pharm. 34(11): 724-27 (1999).
2. The Pharmacopoeia Commission of PRC. The Pharmacopoeia of the People's Republic of China. Part I. Chemical Industry Publishing House, Beijing, China, 2000, p. 177.
3. Y. Kono, H. Shibata, Y. Kodama, and Y. Sawa. The suppression of the N-nitrosating reaction by chlorogenic acid. J. Biochem. 312: 947-53 (1995).
4. M. Ohnishi, H. Morishita, H. Iwahashi, S. Toda, Y. Shirataki, M. Kimura, and R. Kido. Inhibitory effects of chlorogenic acid on linoleic acid peroxidation and haemolysis. Phytochemistry 36: 579-83 (1994).
5. T. Ishii, H. Iwahashi, R. Sugata, R. Kido, and I. Fridovich. Superoxide dismutases enhance the rate of autoxidation of 3-hydroxy anthranilic acid. Arch. Biochem. Biophys. 276(1): 248-50 (1990).
6. X. He, T.M. Zhao, X.D. Jun, and S.S. Gongqi. Pharmacokinetic study on chlorogenic acid. Chin. Trad. Patent. Med. 21(4): 161-62 (1999).
7. T.H. Tsai, Y.F. Chen, A.Y.C. Shum, and C.F. Chen. Determination of chlorogenic acid in rat blood by microdialysis coupled with microbore liquid chromatography and its application to pharmacokinetic studies. J. Chromatogr. A 870: 443-48 (2000).
8. K. Azuma, K. Ippoushi, M.N. Akayama, H. Ito, H. Higashio, and J. Terao. Absorption of chlorogenic acid and caffeic acid in rats after oral administration. J. Agric. Food Chem. 48: 5496-5500 (2000).
9. F. Bressolle, M. Bromet-Petit, and M. Audran. Validation of liquid chromatographic and gas chromatographic methods. Applications to pharmacokinetics. J. Chromatogr. B 686: 3-10 (1996).
10. H.Q. Zhao, J.W. Wu, and J.Q. Gao. Study on the bioavailability of Yinhuang injection, oral solution and tablet. Chin. Trad. Patent. Med. 12(6): 2-4 (1990).