Which screening strategy using BMD measurements would be most cost effective for hip fracture prevention in elderly women? A decision analysis based on a Markov model

Osteoporosis International

Volumn 18, Issue 2, 2007, Pages 143-151

  Schott, A M ^a,b   Ganne, C ^a   Hans, D ^c   Monnier, G ^a   Gauchoux, R ^a   Krieg, M A ^d   Delmas, P D ^b   Meunier, P J ^b   Colin, C ^a  

^a HOSPICES CIVILS DE LYON   (France)

^b EDOUARD HERRIOT HOSPITAL   (France)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

BMD; Cost effectiveness analysis; Markov model; Osteoporosis; Screening

Indexed keywords

AGING; ARTICLE; BONE DENSITOMETRY; BONE DENSITY; COHORT ANALYSIS; COST EFFECTIVENESS ANALYSIS; DECISION MAKING; DECISION TREE; DUAL ENERGY X RAY ABSORPTIOMETRY; HEALTH CARE COST; HIP FRACTURE; PRIORITY JOURNAL; PROBABILITY; PROBABILITY SAMPLE; RISK ASSESSMENT; RISK FACTOR; SCREENING; SCREENING TEST; STATISTICAL MODEL; WOMEN'S HEALTH;

AGED; AGED, 80 AND OVER; BONE DENSITY; COST-BENEFIT ANALYSIS; DECISION TREES; DENSITOMETRY, X-RAY; FEMALE; HIP FRACTURES; HUMANS; MARKOV CHAINS; MONITORING, PHYSIOLOGIC; POSTMENOPAUSE; RISK FACTORS;

EID: 33846247824     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-006-0227-6     Document Type: Article

References (56)

1. WHO (1994) World Health Organization, Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. In. WHO, Geneva
2. Melton LJI, Atkinson EJ, O'Fallon WM, Wahner HW, Riggs BL (1993) Long-term fracture prediction by bone mineral assessed at different skeletal sites. J Bone Miner Res 8:1227-1233
3. Marshall D, Johnell O, Wedel H (1996) Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ 312:1254-1259
4. Schott AM, Cormier C, Hans D, Favier F, Hausherr E, Dargent-Molina P, Delmas PD, Ribot C, Sebert JL, Breart G, Meunier PJ (1998) How hip and whole-body bone mineral density predict hip fracture in elderly women: the EPIDOS Prospective Study. Osteoporos Int 8:247-254
5. Cummings SR, Black DM, Nevitt MC, Browner W, Cauley J, Ensrud K, Genant HK, Palermo L, Scott J, Vogt TM (1993) Bone density at various sites for prediction of hip fractures. The Study of Osteoporotic Fractures Research Group. Lancet 341:72-75
6. Robbins JA, Schott AM, Garnero P, Delmas PD, Hans D, Meunier PJ (2004) Risk factors for hip fracture in women with high BMD: EPIDOS study. Osteoporos Int 8:8
7. Schott AM, Kassai Koupai B, Hans D, Dargent-Molina P, Ecochard R, Bauer DC, Breart G, Meunier PJ (2004) Should age influence the choice of quantitative bone assessment technique in elderly women? The EPIDOS study. Osteoporos Int 15:196-203
8. European-Commission (1998) Report on osteoporosis in the European Community. In: Office for Official Publications of the European Communities, Luxembourg
9. Kanis JA (1997) Diagnosis of osteoporosis. Osteoporos Int 7:S108-116
10. Kanis JA, Black D, Cooper C, Dargent P, Dawson-Hughes B, De Laet C, Delmas P, Eisman J, Johnell O, Jonsson B, Melton L, Oden A, Papapoulos S, Pols H, Rizzoli R, Silman A, Tenenhouse A (2002) A new approach to the development of assessment guidelines for osteoporosis. Osteoporos Int 13:527-536
11. Chapuy MC, Meunier PJ (1998) Pathophysiology and prevention of hip fractures in elderly people. In: Meunier PJ (ed) Osteoporosis: diagnosis and management. Martin Dunitz Ltd, London, pp 191-209
12. Meyer HE, Tverdal A, Falch JA, Pedersen JI (2000) Factors associated with mortality after hip fracture. Osteoporos Int 11:228-232
13. Arden N, Cooper C (1998) Present and future of osteoporosis: epidemiology. In: Meunier PJ (ed) Osteoporosis: diagnosis and management. Martin Dunitz Ltd, London, pp 1-16
14. Jensen JS, Bagger J (1982) Long-term social prognosis after hip fractures. Acta Orthop Scand 53:97-101
15. McClung MR, Geusens P, Miller PD, Zippel H, Bensen WG, Roux C, Adami S, Fogelman I, Diamond T, Eastell R, Meunier PJ, Reginster JY (2001) Effect of risedronate on the risk of hip fracture in elderly women. Hip Intervention Program Study Group. N Engl J Med 344:333-340
16. Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, Bauer DC, Genant HK, Haskell WL, Marcus R, Ott SM, Torner JC, Quandt SA, Reiss TF, Ensrud KE (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet 348:1535-1541
17. Chapuy MC, Arlot ME, Delmas PD, Meunier PJ, Duboeuf F, Brun J, Crouzet B, Arnaud S (1994) Effect of calcium and cholecalciferol treatment for three years on hip fractures in elderly women. BMJ 308:1081-1082
18. Caulin F, Kanis JA, Johnell O, Oden A (2002) Optimal age for preventing osteoporosis after menopause depends on effects of stopping treatment. Bone 30:754-758
19. Kanis JA, Torgerson D, Cooper C (2000) Comparison of the European and USA practice guidelines for Osteoporosis. Trends Endocrinol Metab 11:28-32
20. Weinstein MC, Stason WB (1977) Foundations of cost-effectiveness analysis for health and medical practices. N Engl J Med 296:716-721
21. Drummond MF, O'Brien B, Stoddart GL et al (1997) Methods for the economic evaluation of health care programmes. In Oxford Medical Publications, Oxford
22. Tosteson AN, Gabriel SE, Grove MR, Moncur MM, Kneeland TS, Melton LJ 3rd (2001) Impact of hip and vertebral fractures on quality-adjusted life years. Osteoporos Int 12:1042-1049
23. Sonnenberg FA, Beck JR (1993)Markov models in medical decision making: a practical guide. Med Decis Making 13:322-338
24. Kanis JA, Borgstrom F, Johnell O, Jonsson B (2004) Cost-effectiveness of risedronate for the treatment of osteoporosis and prevention of fractures in postmenopausal women. Osteoporos Int 3:3
25. Baudoin C (1997) [Fractures of the proximal femur. Epidemiology and economic impact]. Presse Med 26:1451-1456
26. Baudoin C, Fardellone P, Bean K, Ostertag-Ezembe A, Hervy F (1996) Clinical outcomes and mortality after hip fracture: a 2-year follow-up study. Bone 18:149S-157S
27. Baudoin C, Fardellone P, Potard V, Sebert JL (1993) Fractures of the proximal femur in Picardy, France, in 1987. Osteoporos Int 3:43-49
28. Jonsson B, Kanis J, Dawson A, Oden A, Johnell O (1999) Effect and offset of effect of treatments for hip fracture on health outcomes. Osteoporos Int 10:193-199
29. Kanis JA, Dawson A, Oden A, Johnell O, de Laet C, Jonsson B (2001) Cost-effectiveness of preventing hip fracture in the general female population. Osteoporos Int 12:356-361
30. Kanis JA, Johnell O, Oden A, De Laet C, Oglesby A, Jonsson B (2002) Intervention thresholds for osteoporosis. Bone 31:26-31
31. Kanis JA, Johnell O, Oden A, De Laet C, Jonsson B, Dawson A (2002) Ten-year risk of osteoporotic fracture and the effect of risk factors on screening strategies. Bone 30:251-258
32. Kanis JA, Johnell O, Oden A, Dawson A, De Laet C, Jonsson B (2001) Ten year probabilities of osteoporotic fractures according to BMD and diagnostic thresholds. Osteoporos Int 12:989-995
33. Watt S (2003) [The cost of screening for breast and cervical cancer in France]. Bull Cancer 90:997-1004
34. Kanis JA, Jonsson B (2002) Economic evaluation of interventions for osteoporosis. Osteoporos Int 13:765-767
35. Maurel FLE, Le Pen C (1998) Le coût hospitalier des fractures ostéoporotiques en France. Journal d'Economie Médicale T.16:99-108
36. Treves R, Arnaud M, Bertin P, Desproges-Gotteron R, Arnaud JP, Pecout D, Dunoyer J (1989) [Evaluation of the hospital cost of femoral neck fractures]. Rev Rhum Mal Osteoartic 56:569
37. Levy E (1989) Cost analysis of osteoporosis related to untreated menopause. Clin Rheumatol 8:76-82
38. Sox HC, Blatt MA, Higgins MC, Marton KI (1988) Medical decision making. Boston
39. Zethraeus N, Johannesson M, Jonsson B, Lothgren M, Tambour M (2003) Advantages of using the net-benefit approach for analysing uncertainty in economic evaluation studies. Pharmacoeconomics 21:39-48
40. Lilliu H, Pamphile R, Chapuy MC, Schulten J, Arlot M, Meunier PJ (2003) Calcium-vitamin D3 supplementation is cost-effective in hip fractures prevention. Maturitas 44:299-305
41. Schousboe JT, Ensrud KE, Nyman JA, Melton LJ 3rd, Kane RL (2005) Universal bone densitometry screening combined with alendronate therapy for those diagnosed with osteoporosis is highly cost-effective for elderly women. J Am Geriatr Soc 53:1697-1704
42. Lips P, van Schoor NM, Melton LJ 3rd, Atkinson EJ, Khosla S, Oberg AL, Riggs BL (2005) Quality of life in patients with osteoporosis evaluation of a prediction model for long-term fracture risk. Osteoporos Int 16:447-455 Epub 2004 Dec 2018
43. Gabriel SE, Kneeland TS, Melton LJ 3rd, Moncur MM, Ettinger B, Tosteson AN (1999) Health-related quality of life in economic evaluations for osteoporosis: whose values should we use? Med Decis Making 19:141-148
44. Abrahamsen B, Stilgren LS, Hermann AP, Tofteng CL, Barenholdt O, Vestergaard P, Brot C, Nielsen SP (2001) Discordance between changes in bone mineral density measured at different skeletal sites in perimenopausal women-implications for assessment of bone loss and response to therapy: The Danish Osteoporosis Prevention Study. J Bone Miner Res 16:1212-1219
45. Nevitt MC, Johnell O, Black DM, Ensrud K, Genant HK, Cummings SR (1994) Bone mineral density predicts non-spine fractures in very elderly women. Study of Osteoporotic Fractures Research Group. Osteoporos Int 4:325-331
46. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ (1992) Vitamin D3 and calcium to prevent hip fractures in the elderly women. N Engl J Med 3271:637-642
47. Meunier PJ, Delmas PD, Eastell R, McClung MR, Papapoulos S, Rizzoli R, Seeman E, Wasnich RD (1999) Diagnosis and management of osteoporosis in postmenopausal women: clinical guidelines. International Committee for Osteoporosis Clinical Guidelines. Clin Ther 21:1025-1044
48. Pols HA, Felsenberg D, Hanley DA, Stepan J, Munoz-Torres M, Wilkin TJ, Qin-sheng G, Galich AM, Vandormael K, Yates AJ, Stych B (1999) Multinational, placebo-controlled, randomized trial of the effects of alendronate on bone density and fracture risk in postmenopausal women with low bone mass: results of the FOSIT study. Fosamax International Trial Study Group. Osteoporos Int 9:461-468
49. Cadarette SM, Jaglal SB, Kreiger N, McIsaac WJ, Darlington GA, Tu JV (2000) Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of women for bone densitometry. CMAJ 162:1289-1294
50. Cadarette SM, Jaglal SB, Murray TM, McIsaac WJ, Joseph L, Brown JP (2001) Evaluation of decision rules for referring women for bone densitometry by dual-energy X-ray absorptiometry. JAMA 286:57-63
51. Ungar WJ, Josse R, Lee S, Ryan N, Adachi R, Hanley D, Brown J, Breton MC (2000) The Canadian SCORE questionnaire: optimizing the use of technology for low bone density assessment. Simple Calculated Osteoporosis Risk Estimate. J Clin Densitom 3:269-280
52. Goemaere S, Zegels B, Toye K, Cremer S, Demuynck R, Daems M, Dobbelaere K, Sedrine WB, Albert A, Dewe W, Kaufman JM, Reginster JY (1999) Limited clinical utility of a self-evaluating risk assessment scale for postmenopausal osteoporosis: lack of predictive value of lifestyle-related factors. Calcif Tissue Int 65:354-358
53. van der Voort DJ, Brandon S, Dinant GJ, van Wersch JW (2000) Screening for osteoporosis using easily obtainable biometrical data: diagnostic accuracy of measured, self-reported and recalled BMI, and related costs of bone mineral density measurements. Osteoporos Int 11:233-239
54. Ben Sedrine W, Devogelaer JP, Kaufman JM, Goemaere S, Depresseux G, Zegels B, Deroisy R, Reginster JY (2001) Evaluation of the simple calculated osteoporosis risk estimation (SCORE) in a sample of white women from Belgium. Bone 29:374-380
55. Amamra N, Berr C, Clavel-Chapelon F, Delcourt C, Delmas P, Derriennic F, Ducimetiere P, Goldberg M, Letenneur L, Rabilloud M, Meunier PJ, Schott AM (2004) Estimated number of women likely to benefit from bone mineral density measurements in France. Joint Bone Spine 75(5):409-418
56. Melton LJ 3rd, Atkinson EJ, Khosla S, Oberg AL, Riggs BL (2005) Evaluation of a prediction model for long-term fracture risk. J Bone Miner Res 20:551-556 Epub 2004 Dec 2006