Disease subsets, antinuclear antibody profile, and clinical features in 127 French and 247 US adult patients with systemic sclerosis

Journal of Rheumatology

Volumn 34, Issue 1, 2007, Pages 104-109

  Meyer, Olivier C ^a,d   Fertig, Noreen ^c   Lucas, Mary ^c   Somogyi, Nathalie ^b   Medsger Jr , Thomas A ^c  

^a Department of Rheumatology ^*  (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^d BICHAT HOSPITAL   (France)

Author keywords

Anti RNA polymerase III; Anti topo I isomerase; Anticentromere; Epidemiology; Systemic sclerosis

Indexed keywords

AUTOANTIBODY; CENTROMERE ANTIBODY; DNA DIRECTED RNA POLYMERASE III; DNA TOPOISOMERASE;

ADULT; ARTHRALGIA; ARTHRITIS; ARTICLE; CALCINOSIS; CLINICAL FEATURE; COHORT ANALYSIS; DISEASE CLASSIFICATION; DISEASE DURATION; DYSPHAGIA; ELECTROCARDIOGRAM; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; FRANCE; HEART ARRHYTHMIA; HEMOGLOBIN DETERMINATION; HUMAN; IMMUNODIFFUSION; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; KIDNEY DISEASE; LUNG FIBROSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RACE DIFFERENCE; RAYNAUD PHENOMENON; SKIN MANIFESTATION; SYSTEMIC SCLEROSIS; THORAX RADIOGRAPHY; UNITED STATES;

ADULT; ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; COHORT STUDIES; DNA TOPOISOMERASES, TYPE I; FEMALE; FIBROSIS; FRANCE; HUMANS; MALE; MIDDLE AGED; PULMONARY FIBROSIS; RNA POLYMERASE III; SCLERODERMA, SYSTEMIC; SKIN DISEASES; UNITED STATES;

EID: 33846232327     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Tan EM, Rodnan GP, Gardia I, Moroi Y, Fritzler MJ, Peebles C. Diversity of antinuclear antibodies in progressive systemic sclerosis. Arthritis Rheum 1980;23:617-25.
2. Okano Y, Steen VD, Medsger TA Jr. Autoantibody reactive with RNA polymerase III in systemic sclerosis. Ann Intern Med 1993;119:1005-13.
3. Steen VD, Powell DL, Medsger TA Jr. Clinical correlations and prognosis based on serum autoantibodies in patients with systemic sclerosis. Arthritis Rheum 1988;31:196-203.
4. Harvey GR, Butts S, Rands AL, Patel Y, McHugh NJ. Clinical and serological associations with anti-RNA polymerase antibodies in systemic sclerosis. Clin Exp Immunol 1999;117:395-402.
5. Mitri GM, Lucas M, Fertig N, Steen VD, Medsger TA Jr. A comparison between anti-Th/To and anticentromere antibody-positive systemic sclerosis patients with limited cutaneous involvement. Arthritis Rheum 2003;48:203-9.
6. Cepeda EJ, Reveille JD. Autoantibodies in systemic sclerosis and fibrosing syndromes: clinical indications and relevance. Curr Opin Rheumatol 2004;16:723-32.
7. McNeilage L, Youngchaiyud U, Whittingham S. Racial differences in antinuclear antibody patterns and clinical manifestations of scleroderma. Arthritis Rheum 1989;32:54-60.
8. Kuwana M, Okano Y, Kaburaki J, Tojo T, Medsger TA Jr. Racial differences in the distribution of systemic sclerosis-related serum antinuclear antibodies. Arthritis Rheum 1994;37:902-6.
9. Reveille JD, Fischbach M, McNearney T, et al, for the GENISOS Study Group. Systemic sclerosis in 3 US ethnic groups: a comparison of clinical, sociodemographic, serologic, and immunogenetic determinants. Semin Arthritis Rheum 2001;30:332-46.
10. Poormoghim H, Lucas M, Fertig N, Medsger TA Jr. Systemic sclerosis sine scleroderma. Arthritis Rheum 2000;43:444-51.
11. Gunduz OH, Fertig N, Lucas M, Medsger TA Jr. Systemic sclerosis with renal crisis and pulmonary hypertension. Arthritis Rheum 2001;44;1663-6.
12. Masi AT, Rodnan GP, Medsger TA Jr, and the Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581-90.
13. Steen VD, Oddis CV, Conte CG, Janosky J, Casterline GZ, Medsger TA Jr. Incidence of systemic sclerosis: a twenty year study of hospital diagnosed cases in Allegheny County, PA, 1963-1982. Arthritis Rheum 1997;40:441-5.
14. Hesselstrand R, Scheja A, Shen GQ, Wiik A, Akesson A. The association of antinuclear antibodies with organ involvement and survival in systemic sclerosis. Rheumatology Oxford 2003;42:534-40.
15. Bunn CC, Demon CP, Shi-Wen X, Knight C, Black CM. Anti-RNA polymerases and other autoantibody specificities in systemic sclerosis. Br J Rheumatol 1998;37:15-20.
16. Bardoni A, Rossi P, Salvini R, Bobbio-Pallavicini F, Caporali R, Montecucco C. Autoantibodies to RNA-polymerase in Italian patients with systemic sclerosis. Clin Exp Rheumatol 2003;21:301-6.
17. Picillo U, Migliaresi S, Vatti S, Marcialis MR, Ferruzzi AM, Tirri G. Demographic differences in the frequencies of scleroderma related autoantibodies. Arthritis Rheum 1993;36:1332-3.