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Volumn 27, Issue 1, 2007, Pages 52-57

Prolactin release in children treated with risperidone: Impact and role of CYP2D6 metabolism

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; PALIPERIDONE; PROLACTIN; RISPERIDONE;

EID: 33846226394     PISSN: 02710749     EISSN: None     Source Type: Journal    
DOI: 10.1097/JCP.0b013e31802e68d5     Document Type: Article
Times cited : (58)

References (38)
  • 1
    • 25144437833 scopus 로고    scopus 로고
    • Use of antipsychotics in children and adolescents
    • Findling RL, Steiner H, Weller EB. Use of antipsychotics in children and adolescents. J Clin Psychiatry. 2005;66(suppl 7):29-40.
    • (2005) J Clin Psychiatry , vol.66 , Issue.SUPPL. 7 , pp. 29-40
    • Findling, R.L.1    Steiner, H.2    Weller, E.B.3
  • 2
    • 25844472161 scopus 로고    scopus 로고
    • Metabolic side effects of atypical antipsychotics in children: A literature review
    • Fedorowicz VJ, Fombonne E. Metabolic side effects of atypical antipsychotics in children: a literature review. J Psychopharmacol. 2005;19:533-550.
    • (2005) J Psychopharmacol , vol.19 , pp. 533-550
    • Fedorowicz, V.J.1    Fombonne, E.2
  • 3
    • 8144221426 scopus 로고    scopus 로고
    • The effect of atypical antipsychotic agents on prolactin levels in children and adolescents
    • Pappagallo M, Silva R. The effect of atypical antipsychotic agents on prolactin levels in children and adolescents. J Child Adolesc Psychopharmacol. 2004;14:359-371.
    • (2004) J Child Adolesc Psychopharmacol , vol.14 , pp. 359-371
    • Pappagallo, M.1    Silva, R.2
  • 4
    • 6344253360 scopus 로고    scopus 로고
    • Antipsychotic-induced hyperprolactinaemia: Mechanisms, clinical features and management
    • Haddad PM, Wieck A. Antipsychotic-induced hyperprolactinaemia: mechanisms, clinical features and management. Drugs. 2004;64:2291-2314.
    • (2004) Drugs , vol.64 , pp. 2291-2314
    • Haddad, P.M.1    Wieck, A.2
  • 5
    • 0033405513 scopus 로고    scopus 로고
    • Elevated prolactin in pediatric patients on typical and atypical antipsychotics
    • Wudarsky M, Nicolson R, Hamburger SD, et al. Elevated prolactin in pediatric patients on typical and atypical antipsychotics. J Child Adolesc Psychopharmacol. 1999;9:239-245.
    • (1999) J Child Adolesc Psychopharmacol , vol.9 , pp. 239-245
    • Wudarsky, M.1    Nicolson, R.2    Hamburger, S.D.3
  • 7
    • 2442623366 scopus 로고    scopus 로고
    • Growth and sexual maturation during long-term treatment with risperidone
    • Dunbar F, Kusumakar V, Daneman D, et al. Growth and sexual maturation during long-term treatment with risperidone. Am J Psychiatry. 2004;161:918-920.
    • (2004) Am J Psychiatry , vol.161 , pp. 918-920
    • Dunbar, F.1    Kusumakar, V.2    Daneman, D.3
  • 8
    • 0344119561 scopus 로고    scopus 로고
    • Prolactin levels during long-term risperidone treatment in children and adolescents
    • Findling RL, Kusumakar V, Daneman D, et al. Prolactin levels during long-term risperidone treatment in children and adolescents. J Clin Psychiatry. 2003;64:1362-1369.
    • (2003) J Clin Psychiatry , vol.64 , pp. 1362-1369
    • Findling, R.L.1    Kusumakar, V.2    Daneman, D.3
  • 9
    • 33846562907 scopus 로고    scopus 로고
    • Effects of short- and long-term risperidone treatment on prolactin levels in children with autism
    • In press
    • Anderson GM, Scahill L, McCracken JT, et al. Effects of short- and long-term risperidone treatment on prolactin levels in children with autism. Biol Psychiatry. In press.
    • Biol Psychiatry
    • Anderson, G.M.1    Scahill, L.2    McCracken, J.T.3
  • 10
    • 29944432379 scopus 로고    scopus 로고
    • Elevated prolactin levels in male youths treated with risperidone and quetiapine
    • Stevens JR, Kymissis PI, Baker AJ. Elevated prolactin levels in male youths treated with risperidone and quetiapine. J Child Adolesc Psychopharmacol. 2005;15:893-900.
    • (2005) J Child Adolesc Psychopharmacol , vol.15 , pp. 893-900
    • Stevens, J.R.1    Kymissis, P.I.2    Baker, A.J.3
  • 11
    • 0038218022 scopus 로고    scopus 로고
    • Risperidone-associated ejaculatory and urinary dysfunction in male adolescents
    • Holtmann M, Gerstner S, Schmidt MH. Risperidone-associated ejaculatory and urinary dysfunction in male adolescents. J Child Adolesc Psychopharmacol. 2003;13:107-109.
    • (2003) J Child Adolesc Psychopharmacol , vol.13 , pp. 107-109
    • Holtmann, M.1    Gerstner, S.2    Schmidt, M.H.3
  • 12
    • 0037355002 scopus 로고    scopus 로고
    • Risperidone-induced galactorrhoea: A case series
    • Gupta SC, Jagadheesan K, Basu S, et al. Risperidone-induced galactorrhoea: a case series. Can J Psychiatry. 2003;48:130-131.
    • (2003) Can J Psychiatry , vol.48 , pp. 130-131
    • Gupta, S.C.1    Jagadheesan, K.2    Basu, S.3
  • 13
    • 3442875587 scopus 로고    scopus 로고
    • The role of cytochrome P450 enzymes in the metabolism of risperidone and its clinical relevance for drug interactions
    • Berecz R, Dorado P, De La RA, et al. The role of cytochrome P450 enzymes in the metabolism of risperidone and its clinical relevance for drug interactions. Curr Drug Targets. 2004;5:573-579.
    • (2004) Curr Drug Targets , vol.5 , pp. 573-579
    • Berecz, R.1    Dorado, P.2    De La, R.A.3
  • 14
    • 0027436269 scopus 로고
    • Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects
    • Huang ML, Van Peer A, Woestenborghs R, et al. Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects. Clin Pharmacol Ther. 1993;54:257-268.
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 257-268
    • Huang, M.L.1    Van Peer, A.2    Woestenborghs, R.3
  • 15
    • 0009404019 scopus 로고    scopus 로고
    • Pharmacokinetics of clozapine and risperidone: A review of recent literature
    • Byerly MJ, DeVane CL. Pharmacokinetics of clozapine and risperidone: a review of recent literature. J Clin Psychopharmacol. 1996;16:177-187.
    • (1996) J Clin Psychopharmacol , vol.16 , pp. 177-187
    • Byerly, M.J.1    DeVane, C.L.2
  • 16
    • 0030863726 scopus 로고    scopus 로고
    • Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in serum from patients comedicated with other psychotropic drugs
    • Olesen OV, Linnet K. Simplified high-performance liquid chromatographic method for determination of risperidone and 9-hydroxyrisperidone in serum from patients comedicated with other psychotropic drugs. J Chromatogr B Biomed Sci Appl. 1997;698:209-216.
    • (1997) J Chromatogr B Biomed Sci Appl , vol.698 , pp. 209-216
    • Olesen, O.V.1    Linnet, K.2
  • 17
    • 0028237637 scopus 로고
    • Risperidone: A novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity
    • Leysen JE, Janssen PM, Megens AA, et al. Risperidone: a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity. J Clin Psychiatry. 1994;55 suppl:5-12.
    • (1994) J Clin Psychiatry , vol.55 , Issue.SUPPL. , pp. 5-12
    • Leysen, J.E.1    Janssen, P.M.2    Megens, A.A.3
  • 18
    • 0028332094 scopus 로고
    • Survey on the pharmacodynamics of the new antipsychotic risperidone
    • Megens AA, Awouters FH, Schotte A, et al. Survey on the pharmacodynamics of the new antipsychotic risperidone. Psychopharmacology (Berl). 1994;114:9-23.
    • (1994) Psychopharmacology (Berl) , vol.114 , pp. 9-23
    • Megens, A.A.1    Awouters, F.H.2    Schotte, A.3
  • 19
    • 0028989238 scopus 로고
    • A PET study of D2 and 5-HT2 receptor occupancy induced by risperidone in poor metabolizers of debrisoquin and risperidone
    • Nyberg S, Dahl ML, Halldin C. A PET study of D2 and 5-HT2 receptor occupancy induced by risperidone in poor metabolizers of debrisoquin and risperidone. Psychopharmacology (Berl). 1995;119:345-348.
    • (1995) Psychopharmacology (Berl) , vol.119 , pp. 345-348
    • Nyberg, S.1    Dahl, M.L.2    Halldin, C.3
  • 20
    • 0033987060 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone
    • Scordo MG, Spina E, Facciola G, et al. Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone. Psychopharmacology (Berl). 1999;147:300-305.
    • (1999) Psychopharmacology (Berl) , vol.147 , pp. 300-305
    • Scordo, M.G.1    Spina, E.2    Facciola, G.3
  • 21
    • 0038103561 scopus 로고    scopus 로고
    • Effects of various CYP2D6 genotypes on the steady-state plasma concentrations of risperidone and its active metabolite, 9-hydroxyrisperidone, in Japanese patients with schizophrenia
    • Mihara K, Kondo T, Yasui-Furukori N, et al. Effects of various CYP2D6 genotypes on the steady-state plasma concentrations of risperidone and its active metabolite, 9-hydroxyrisperidone, in Japanese patients with schizophrenia. Ther Drug Monit. 2003;25:287-293.
    • (2003) Ther Drug Monit , vol.25 , pp. 287-293
    • Mihara, K.1    Kondo, T.2    Yasui-Furukori, N.3
  • 22
    • 13844320650 scopus 로고    scopus 로고
    • The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation
    • de Leon J, Susce MT, Pan RM, et al. The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation. J Clin Psychiatry. 2005;66:15-27.
    • (2005) J Clin Psychiatry , vol.66 , pp. 15-27
    • de Leon, J.1    Susce, M.T.2    Pan, R.M.3
  • 23
    • 18744408824 scopus 로고    scopus 로고
    • Predominant role of the 9-hydroxy metabolite of risperidone in elevating blood prolactin levels
    • Knegtering R, Baselmans P, Castelein S, et al. Predominant role of the 9-hydroxy metabolite of risperidone in elevating blood prolactin levels. Am J Psychiatry. 2005;162:1010-1012.
    • (2005) Am J Psychiatry , vol.162 , pp. 1010-1012
    • Knegtering, R.1    Baselmans, P.2    Castelein, S.3
  • 24
    • 27144532065 scopus 로고    scopus 로고
    • Long-term effects of risperidone in children with autism spectrum disorders: A placebo discontinuation study
    • Troost PW, Lahuis BE, Steenhuis MP, et al. Long-term effects of risperidone in children with autism spectrum disorders: a placebo discontinuation study. J Am Acad Child Adolesc Psychiatry. 2005;44:1137-1144.
    • (2005) J Am Acad Child Adolesc Psychiatry , vol.44 , pp. 1137-1144
    • Troost, P.W.1    Lahuis, B.E.2    Steenhuis, M.P.3
  • 25
    • 0029102348 scopus 로고
    • Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology
    • Steen VM, Andreassen OA, Daly AK, et al. Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology. Pharmacogenetics. 1995;5:215-223.
    • (1995) Pharmacogenetics , vol.5 , pp. 215-223
    • Steen, V.M.1    Andreassen, O.A.2    Daly, A.K.3
  • 26
    • 0007293059 scopus 로고    scopus 로고
    • Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene
    • Lovlie R, Daly AK, Molven A, et al. Ultrarapid metabolizers of debrisoquine: characterization and PCR-based detection of alleles with duplication of the CYP2D6 gene. FEBS Lett. 1996;392:30-34.
    • (1996) FEBS Lett , vol.392 , pp. 30-34
    • Lovlie, R.1    Daly, A.K.2    Molven, A.3
  • 27
    • 0036682267 scopus 로고    scopus 로고
    • Risperidone in children with autism for serious behavioral problems
    • RUPP, Research Units on Pediatric Psychopharmacology Autism Network
    • RUPP, Research Units on Pediatric Psychopharmacology Autism Network. Risperidone in children with autism for serious behavioral problems. N Engl J Med. 2002;347:314-321.
    • (2002) N Engl J Med , vol.347 , pp. 314-321
  • 28
    • 0003021979 scopus 로고
    • Jonckheere test for ordered alternatives
    • Kotz S, Johnson NL, eds, New York: John Wiley & Sons, Inc;
    • Pirie W. Jonckheere test for ordered alternatives. In: Kotz S, Johnson NL, eds. Encyclopedia of Statistical Sciences, vol 4. New York: John Wiley & Sons, Inc; 1983:315-318.
    • (1983) Encyclopedia of Statistical Sciences , vol.4 , pp. 315-318
    • Pirie, W.1
  • 29
    • 0028804854 scopus 로고    scopus 로고
    • Soldin SJ, Morales A, Albalos F, et al. Pediatric reference ranges on the Abbott IMx for FSH, LH, prolactin, TSH, T4, T3, free T4, free T3, T-uptake, IgE, and ferritin. Clin Biochem. 1995;28:603-606.
    • Soldin SJ, Morales A, Albalos F, et al. Pediatric reference ranges on the Abbott IMx for FSH, LH, prolactin, TSH, T4, T3, free T4, free T3, T-uptake, IgE, and ferritin. Clin Biochem. 1995;28:603-606.
  • 30
    • 0032952480 scopus 로고    scopus 로고
    • Prolactin levels and adverse events in patients treated with risperidone
    • Kleinberg DL, Davis JM, De Coster R, et al. Prolactin levels and adverse events in patients treated with risperidone. J Clin Psychopharmacol. 1999;19:57-61.
    • (1999) J Clin Psychopharmacol , vol.19 , pp. 57-61
    • Kleinberg, D.L.1    Davis, J.M.2    De Coster, R.3
  • 31
    • 0036218484 scopus 로고    scopus 로고
    • The effects of antipsychotic- induced hyperprolactinaemia on the hypothalamic-pituitary-gonadal axis
    • Smith S, Wheeler MJ, Murray R, et al. The effects of antipsychotic- induced hyperprolactinaemia on the hypothalamic-pituitary-gonadal axis. J Clin Psychopharmacol. 2002;22:109-114.
    • (2002) J Clin Psychopharmacol , vol.22 , pp. 109-114
    • Smith, S.1    Wheeler, M.J.2    Murray, R.3
  • 32
    • 0037376682 scopus 로고    scopus 로고
    • Prevalence of hyperprolactinemia in schizophrenic patients treated with conventional antipsychotic medications or risperidone
    • Kinon BJ, Gilmore JA, Liu H, et al. Prevalence of hyperprolactinemia in schizophrenic patients treated with conventional antipsychotic medications or risperidone. Psychoneuroendocrinology. 2003;28(suppl 2):55-68.
    • (2003) Psychoneuroendocrinology , vol.28 , Issue.SUPPL. 2 , pp. 55-68
    • Kinon, B.J.1    Gilmore, J.A.2    Liu, H.3
  • 33
    • 29944441899 scopus 로고    scopus 로고
    • Risperidone-induced prolactin elevation in a prospective study of children, adolescents, and adults with mental retardation and pervasive developmental disorders
    • Hellings JA, Zarcone JR, Valdovinos MG, et al. Risperidone-induced prolactin elevation in a prospective study of children, adolescents, and adults with mental retardation and pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2005;15:885-892.
    • (2005) J Child Adolesc Psychopharmacol , vol.15 , pp. 885-892
    • Hellings, J.A.1    Zarcone, J.R.2    Valdovinos, M.G.3
  • 34
    • 0036718143 scopus 로고    scopus 로고
    • Long-term safety and efficacy of risperidone for the treatment of disruptive behavior disorders in children with subaverage IQs
    • Turgay A, Binder C, Snyder R, et al. Long-term safety and efficacy of risperidone for the treatment of disruptive behavior disorders in children with subaverage IQs. Pediatrics. 2002;110:e34.
    • (2002) Pediatrics , vol.110
    • Turgay, A.1    Binder, C.2    Snyder, R.3
  • 35
    • 0036768952 scopus 로고    scopus 로고
    • The effects of atypical antipsychotics on serum prolactin levels
    • Hamner M. The effects of atypical antipsychotics on serum prolactin levels. Ann Clin Psychiatry. 2002;14:163-173.
    • (2002) Ann Clin Psychiatry , vol.14 , pp. 163-173
    • Hamner, M.1
  • 36
    • 11144221180 scopus 로고    scopus 로고
    • Codeine intoxication associated with ultrarapid CYP2D6 metabolism
    • Gasche Y, Daali Y, Fathi M, et al. Codeine intoxication associated with ultrarapid CYP2D6 metabolism. N Engl J Med. 2004;351:2827-2831.
    • (2004) N Engl J Med , vol.351 , pp. 2827-2831
    • Gasche, Y.1    Daali, Y.2    Fathi, M.3
  • 37
    • 0032776927 scopus 로고    scopus 로고
    • A pilot study on risperidone metabolism: The role of cytochromes P450 2D6 and 3A
    • Bork JA, Rogers T, Wedlund PJ, et al. A pilot study on risperidone metabolism: the role of cytochromes P450 2D6 and 3A. J Clin Psychiatry. 1999;60:469-476.
    • (1999) J Clin Psychiatry , vol.60 , pp. 469-476
    • Bork, J.A.1    Rogers, T.2    Wedlund, P.J.3
  • 38
    • 33748624897 scopus 로고    scopus 로고
    • Characterization of variant alleles of cytochrome CYP2D6 in a Spanish population
    • Menoyo A, Del Rio E, Baiget M. Characterization of variant alleles of cytochrome CYP2D6 in a Spanish population. Cell Biochem Funct. 2006;24:381-385.
    • (2006) Cell Biochem Funct , vol.24 , pp. 381-385
    • Menoyo, A.1    Del Rio, E.2    Baiget, M.3


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