Sex differences in the familial transmission of mood disorders

Journal of Affective Disorders

Volumn 95, Issue 1-3, 2006, Pages 51-60

  Currier, Dianne ^a   Mann, Mark J ^a   Oquendo, Maria A ^a   Galfalvy, Hanga ^a   Mann, John J ^a  

^a New York State Psychiatric Institute/Columbia University College of Physicians and Surgeons New York ^*  (United States)

Author keywords

Heritability; Mood disorders; Sex differences

Indexed keywords

ADULT; AGGRESSION; ANAMNESIS; ARTICLE; CHILD ABUSE; COMORBIDITY; DISEASE TRANSMISSION; FAMILIAL DISEASE; FEMALE; GENETIC DISORDER; GENETIC RISK; HUMAN; IMPULSIVENESS; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MOOD DISORDER; MULTIVARIATE ANALYSIS; PREVALENCE; PRIORITY JOURNAL; PROGENY; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE;

ADULT; BIPOLAR DISORDER; BORDERLINE PERSONALITY DISORDER; COMORBIDITY; CROSS-SECTIONAL STUDIES; DEPRESSIVE DISORDER, MAJOR; FATHERS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MODELS, STATISTICAL; MOTHERS; MULTIVARIATE ANALYSIS; SEX FACTORS; STATISTICS, NONPARAMETRIC;

EID: 33846206947     PISSN: 01650327     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jad.2006.04.014     Document Type: Article

References (79)

1. Akiskal H.S., and Benazzi F. The DSM-IV and ICD-10 categories of recurrent [major] depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum. J. Affect. Disord. 92 1 (2006) 45-54
2. Akiskal H.S., Maser J.D., Zeller P.J., Endicott J., Coryell W., Keller M., Warshaw M., Clayton P., and Goodwin F. Switching from 'unipolar' to bipolar II. An 11-year prospective study of clinical and temperamental predictors in 559 patients. Arch. Gen. Psychiatry 52 (1995) 114-123
3. Andreasen N.C., Endicott J., Spitzer R.L., and Winokur G. The family history method using diagnostic criteria: reliability and validity. Arch. Gen. Psychiatry 34 (1977) 1229-1235
4. Andreasen N., Rice J., Endicott J., Reich T., and Coryell W. The family history approach to diagnosis: how useful is it?. Arch. Gen. Psychiatry 43 (1986) 421-429
5. Angst J., Sellaro R., Stassen H.H., and Gamma A. Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissions. J. Affect. Disord. 84 (2005) 149-157
6. Barratt E.S. Factor analysis of some psychometric measures of impulsiveness and anxiety. Psychol. Rep. 16 (1965) 547-554
7. Beardslee W.R., Keller M.B., Lavori P.W., Staley J., and Sacks N. The impact of parental affective disorder on depression in offspring: a longitudinal follow-up in a nonreferred sample. J. Am. Acad. Child Adolesc. Psych. 32 (1993) 723-730
8. Beardslee W.R., Versage E.M., and Gladstone T.R. Children of affectively ill parents: a review of the past 10 years. J. Am. Acad. Child Adolesc. Psych. 37 (1998) 1134-1141
9. Beck A.T., Ward C.H., Mendelson M., Mock J., and Erbaugh J. An inventory for measuring depression. Arch. Gen. Psychiatry 4 (1961) 53-63
10. Bierut L.J., Heath A.C., Bucholz K.K., Dinwiddie S.H., Madden P.A., Statham D.J., Dunne M.P., and Martin N.G. Major depressive disorder in a community-based twin sample: are there different genetic and environmental contributions for men and women?. Arch. Gen. Psychiatry 56 (1999) 557-563
11. Bifulco A., Moran P.M., Ball C., Jacobs C., Baines R., Bunn A., and Cavagin J. Childhood adversity, parental vulnerability and disorder: examining inter-generational transmission of risk. J. Child Psychol. Psychiatry 43 (2002) 1075-1086
12. Brennan P.A., Hammen C., Katz A.R., and Le Brocque R.M. Maternal depression, paternal psychopathology, and adolescent diagnostic outcomes. J. Consult. Clin. Psychol. 70 (2002) 1075-1085
13. Brent D.A., Oquendo M., Birmaher B., Greenhill L., Kolko D., Stanley B., Zelazny J., Brodsky B., Bridge J., Ellis S., Salazar J.O., and Mann J.J. Familial pathways to early-onset suicide attempt: risk for suicidal behavior in offspring of mood-disordered suicide attempters. Arch. Gen. Psychiatry 59 (2002) 801-807
14. Brent D.A., Oquendo M., Birmaher B., Greenhill L., Kolko D., Stanley B., Zelazny J., Brodsky B., Melhem N., Ellis S.P., and Mann J.J. Familial transmission of mood disorders: convergence and divergence with transmission of suicidal behavior. J. Am. Acad. Child Adolesc. Psych. 43 (2004) 1259-1266
15. Brown G.L., and Goodwin F.K. Human aggression and suicide. Suicide Life-Threat. Behav. 16 (1986) 223-243
16. Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., McClay J., Mill J., Martin J., Braithwaite A., and Poulton R. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301 (2003) 386-389
17. Connell A.M., and Goodman S.H. The association between psychopathology in fathers versus mothers and children's internalizing and externalizing behavior problems: a meta-analysis. Psychol. Bull. 128 (2002) 746-773
18. Coohey C., and Braun N. Toward an integrated framework for understanding child physical abuse. Child Abuse Negl. 21 (1997) 1081-1094
19. Coryell W., Endicott J., Maser J.D., Keller M.B., Leon A.C., and Akiskal H.S. Long-term stability of polarity distinctions in the affective disorders. Am. J. Psychiatry 152 (1995) 385-390
20. Dixon L., Browne K., and Hamilton-Giachritsis C. Risk factors of parents abused as children: a mediational analysis of the intergenerational continuity of child maltreatment (Part I). J. Child Psychol. Psychiatry 46 (2005) 47-57
21. Downey G., and Coyne J.C. Children of depressed parents: an integrative review. Psychol. Bull. 108 (1990) 50-76
22. Fergusson D.M., Horwood L.J., and Lynskey M.T. Maternal depressive symptoms and depressive symptoms in adolescents. J. Child Psychol. Psychiatry 36 (1995) 1161-1178
23. First M.B., Spitzer R.L., Gibbon M., Williams J.M.G., and Benjamin L. Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II), (Version 2.0) (1996), Biometrics Research Department, New York State Psychiatric Institute, New York
24. Foley D.L., Pickles A., Simonoff E., Maes H.H., Silberg J.L., Hewitt J.K., and Eaves L.J. Parental concordance and comorbidity for psychiatric disorder and associate risks for current psychiatric symptoms and disorders in a community sample of juvenile twins. J. Child Psychol. Psychiatry 42 (2001) 381-394
25. Gershon E.S., Hamovit J., Guroff J.J., Dibble E., Leckman J.F., Sceery W., Targum S.D., Nurnberger Jr. J.I., Goldin L.R., and Bunney Jr. W.E. A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. Arch. Gen. Psychiatry 39 (1982) 1157-1167
26. Goldberg J.F., Harrow M., and Whiteside J.E. Risk for bipolar illness in patients initially hospitalized for unipolar depression. Am. J. Psychiatry 158 (2001) 1265-1270
27. Grigoroiu-Serbanescu M., Martinez M., Nöthen M.M., Propping P., Milea S., Mihailescu R., and Marinescu E. Patterns of parental transmission and familial aggregation models in bipolar affective disorder. Am. J. Med. Genet. 81 (1998) 397-404
28. Hamilton M. A rating scale for depression. J. Neurol. Neurosurg. Psychiatry 23 (1960) 56-62
29. Hammen C., and Brennan P.A. Severity, chronicity, and timing of maternal depression and risk for adolescent offspring diagnoses in a community sample. Arch. Gen. Psychiatry 60 (2003) 253-258
30. Hammen C., Burge D., Burney E., and Adrian C. Longitudinal study of diagnoses in children of women with unipolar and bipolar affective disorder. Arch. Gen. Psychiatry 47 (1990) 1112-1117
31. Hammen C., Brennan P.A., and Shih J.H. Family discord and stress predictors of depression and other disorders in adolescent children of depressed and nondepressed women. J. Am. Acad. Child Adolesc. Psych. 43 (2004) 994-1002
32. Johnson J.G., Cohen P., Kasen S., Smailes E., and Brook J.S. Association of maladaptive parental behavior with psychiatric disorder among parents and their offspring. Arch. Gen. Psychiatry 58 (2001) 453-460
33. Kane P., and Garber J. The relations among depression in fathers, children's psychopathology, and father-child conflict: a meta-analysis. Clin. Psychol. Rev. 24 (2004) 339-360
34. Kaufman J., Yang B.Z., Douglas-Palumberi H., Houshyar S., Lipschitz D., Krystal J.H., and Gelernter J. Social supports and serotonin transporter gene moderate depression in maltreated children. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 17316-17321
35. Keller M.B., Beardslee W.R., Dorer D.J., Lavori P.W., Samuelson H., and Klerman G.R. Impact of severity and chronicity of parental affective illness on adaptive functioning and psychopathology in children. Arch. Gen. Psychiatry 43 (1986) 930-937
36. Kendler K.S. Twin studies of psychiatric illness: an update. Arch. Gen. Psychiatry 58 (2001) 1005-1014
37. Kendler K.S., and Davis C. The familial aggregation of common psychiatric and substance use disorders in the National Comorbidity Survey: a family history study. Br. J. Psychiatry 170 (1997) 541-548
38. Kendler K.S., Gardner C.O., Neale M.C., and Prescott C.A. Genetic risk factors for major depression in men and women: similar or different heritabilities and same or partly distinct genes?. Psychol. Med. 31 (2001) 605-616
39. Kessler R.C., Chiu W.T., Demler O., Merikangas K.R., and Walters E.E. Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry 62 (2005) 617-627
40. Klein D.N., Lewinsohn P.M., Seeley J.R., and Rohde P.A. family study of major depressive disorder in a community sample of adolescents. Arch. Gen. Psychiatry 58 (2001) 13-20
41. Klein D.N., Lewinsohn P.M., Rohde P., Seeley J.R., and Olino T.M. Psychopathology in the adolescent and young adult offspring of a community sample of mothers and fathers with major depression. Psychol. Med. 35 (2005) 353-365
42. Kovacs M., Devlin B., Pollock M., Richards C., and Mukerji P. A controlled family history study of childhood-onset depressive disorder. Arch. Gen. Psychiatry 54 (1997) 613-623
43. Lieb R., Isensee B., Hofler M., Pfister H., and Wittchen H.U. Parental major depression and the risk of depression and other mental disorders in offspring: a prospective-longitudinal community study. Arch. Gen. Psychiatry 59 (2002) 365-374
44. Lyons M.J., Eisen S.A., Goldberg J., True W., Lin N., Meyer J.M., Toomey R., Faraone S.V., Merla-Ramos M., and Tsuang M.T. A registry-based twin study of depression in men. Arch. Gen. Psychiatry 55 (1998) 468-472
45. Mann J.J., Bortinger J., Oquendo M.A., Currier D., Li S., and Brent D.A. Family history of suicidal behavior and mood disorders in probands with mood disorders. Am. J. Psychiatry 162 (2005) 1672-1679
46. McGue M., and Christensen K. Genetic and environmental contributions to depression symptomatology: evidence from Danish twins 75 years of age and older. J. Abnorm. Psychology 106 (1997) 439-448
47. McGuffin P., Katz R., Watkins S., and Rutherford J. A hospital-based twin register of the heritability of DSM-IV unipolar depression. Arch. Gen. Psychiatry 53 (1996) 129-136
48. McGuffin P., Rijsdijk F., Andrew M., Sham P., Katz R., and Cardno A. The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch. Gen. Psychiatry 60 (2003) 497-502
49. McMahon F.J., Stine O.C., Chase G.A., Meyers D.A., Simpson S.G., and De Paulo Jr. J.R. Influence of clinical subtype, sex, and linearity on age at onset of major affective disorder in a family sample. Am. J. Psychiatry 151 (1994) 210-215
50. Mendlewicz J., and Baron M. Morbidity risks in subtypes of unipolar depressive illness: differences between early and late onset forms. Br. J. Psychiatry 139 (1981) 463-466
51. Mitchell J., McCauley E., Burke P., Calderon R., and Schloredt K. Psychopathology in parents of depressed children and adolescents. J. Am. Acad. Child Adolesc. Psych. 28 (1989) 352-357
52. Nelson E.C., Heath A.C., Madden P.A., Cooper M.L., Dinwiddie S.H., Bucholz K.K., Glowinski A., McLaughlin T., Dunne M.P., Statham D.J., and Martin N.G. Association between self-reported childhood sexual abuse and adverse psychosocial outcomes: results from a twin study. Arch. Gen. Psychiatry 59 (2002) 139-145
53. Newcomb M.D., and Locke T.F. Intergenerational cycle of maltreatment: a popular concept obscured by methodological limitations. Child Abuse Negl. 25 (2001) 1219-1240
54. Nomura Y., Warner V., and Wickramaratne P. Parents concordant for major depressive disorder and the effect of psychopathology in offspring. Psychol. Med. 31 (2001) 1211-1222
55. Nomura Y., Wickramaratne P.J., Warner V., Mufson L., and Weissman M.M. Family discord, parental depression, and psychopathology in offspring: ten-year follow-up. J. Am. Acad. Child Adolesc. Psych. 41 (2002) 402-409
56. Oquendo M.A., Galfalvy H., Russo S., Ellis S.P., Grunebaum M.F., Burke A., and Mann J.J. Prospective study of clinical predictors of suicidal acts after a major depressive episode in patients with major depressive disorder or bipolar disorder. Am. J. Psychiatry 161 (2004)
57. Orvaschel H., Walsh-Allis G., and Ye W.J. Psychopathology in children of parents with recurrent depression. J. Abnorm. Child Psychol. 16 (1988) 17-28
58. Pears K.C., and Capaldi D.M. Intergenerational transmission of abuse: a two-generational prospective study of an at-risk sample. Child Abuse Negl. 25 (2001) 1439-1461
59. Phares V., and Compas B.E. The role of fathers in child and adolescent psychopathology: make room for daddy. Psychol. Bull. 111 (1992) 387-412
60. Reich T., Van Eerdewegh P., Rice J., Mullaney J., Endicott J., and Klerman G.L. The familial transmission of primary major depressive disorder. J. Psychiatr. Res. 21 (1987) 613-624
61. Rice J., Reich T., Andreasen N.C., Lavori P.W., Endicott J., Clayton P.J., Keller M.B., Hirschfeld R.M., and Klerman G.L. Sex-related differences in depression. Familial evidence. J. Affect. Disord. 7 (1984) 199-210
62. Shiner R.L., and Marmorstein N.R. Family environments of adolescents with lifetime depression: associations with maternal depression history. J. Am. Acad. Child Adolesc. Psych. 37 (1998) 1152-1160
63. Smoller J.W., and Finn C.T. Family, twin, and adoption studies of bipolar disorder. Am. J. Med. Genet. 123C (2003) 48-58
64. Spitzer R.L., Williams J.B.W., Gibbon M., and First M.B. Structured Clinical Interview for DSM-III-R. Patient Edition (SCID-P) (1990), American Psychiatric Press, Washington, DC
65. Sullivan P.F., Neale M.C., and Kendler S. Genetic epidemiology of major depression: review and meta-analysis. Am. J. Psychiatry 157 (2000) 1552-1562
66. Tisher M., Tonge B.J., and Horne D.J. Childhood depression, stressors and parental depression. Aust. N. Z. J. Psychiatry 28 (1994) 635-641
67. Weissman M.M., Leckman J.F., Merikangas K.R., Gammon G.D., and Prusoff B.A. Depression and anxiety disorders in parents and children. Results from the Yale family study. Arch. Gen. Psychiatry 41 (1984) 845-852
68. Weissman M.M., Prusoff B.A., Gammon G.D., Merikangas K.R., Leckman J.F., and Kidd K.K. Psychopathology in the children (ages 6-18) of depressed and normal parents. J. Am. Acad. Child Psych. 23 (1984) 78-84
69. Weissman M.M., Wickramaratne P., Merikangas K.R., Leckman J.F., Prusoff B.A., Caruso K.A., Kidd K.K., and Gammon G.D. Onset of major depression in early adulthood. Increased familial loading and specificity. Arch. Gen. Psychiatry 41 (1984) 1136-1143
70. Weissman M.M., Merikangas K.R., Wickramaratne P., Kidd K.K., Prusoff B.A., Leckman J.F., and Pauls D.L. Understanding the clinical heterogeneity of major depression using family data. Arch. Gen. Psychiatry 43 (1986) 430-434
71. Weissman M.M., Warner V., Wickramaratne P., and Prusoff B.A. Early-onset major depression in parents and their children. J. Affect. Disord. 15 (1988) 269-277
72. Weissman M.M., Warner V., Wickramaratne P., Moreau D., and Olfson M. Offspring of depressed parents. 10 years later. Arch. Gen. Psychiatry 54 (1997) 932-940
73. Wickramaratne P.J., and Weissman M.M. Onset of psychopathology in offspring by developmental phase and parental depression. J. Am. Acad. Child Adolesc. Psych. 37 (1998) 933-942
74. Wickramaratne P.J., Warner V., and Weissman M.M. Selecting early onset MDD probands for genetic studies: results from a longitudinal high-risk study. Am. J. Med. Genet. 96 (2000) 93-101
75. Winokur G., and Clayton P. Family history studies: II. Sex differences and alcoholism in primary affective illness. Br. J. Psychiatry 113 (1967) 973-979
76. Young E.A., Abelson J.L., Curtis G.C., and Nesse R.M. Childhood adversity and vulnerability to mood and anxiety disorders. Depress. Anxiety 5 (1997) 66-72
77. Zeger S.L., and Liang K.Y. Longitudinal data analysis for discrete and continuous outcomes. Biometrics 42 (1986) 121-130
78. Zubenko G.S., Hughes III H.B., Stiffler J.S., Zubenko W.N., and Kaplan B.B. D2S2944 identifies a likely susceptibility locus for recurrent, early-onset, major depression in women. Mol. Psychiatry 7 (2002) 460-467
79. Zubenko G.S., Hughes III H.B., Maher B.S., Stiffler J.S., Zubenko W.N., and Marazita M.L. Genetic linkage of region containing the CREB1 gene to depressive disorders in women from families with recurrent, early-onset, major depression. Am. J. Med. Genet. 114 (2002) 980-987