-
1
-
-
0033592991
-
Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A)
-
Crowder K.M., Gunther J.M., Jones T.A., Hale B.D., Zhang H.Z., Peterson M.R., et al. Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A). Proc Natl Acad Sci 96 (1999) 15268-15273
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 15268-15273
-
-
Crowder, K.M.1
Gunther, J.M.2
Jones, T.A.3
Hale, B.D.4
Zhang, H.Z.5
Peterson, M.R.6
-
2
-
-
3042748137
-
The Synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
-
Lynch B., Lambeng N., Nocka K., et al. The Synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci 101 (2004) 9861-9866
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 9861-9866
-
-
Lynch, B.1
Lambeng, N.2
Nocka, K.3
-
3
-
-
9144238050
-
Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity
-
Kenda B.M., Matagne A.C., Talaga P.E., Pasau P.M., Differding E., Lallemand B.I., et al. Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity. Journal of Medicinal Chemistry 47 (2004) 530-549
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, pp. 530-549
-
-
Kenda, B.M.1
Matagne, A.C.2
Talaga, P.E.3
Pasau, P.M.4
Differding, E.5
Lallemand, B.I.6
-
5
-
-
4644273656
-
ucb 34714, a new pyrrolidone derivative: comparison with levetiracetam in hippocampal slice epilepsy models in vitro
-
Margineanu D.-G., Kenda B.M., Michel P., Matagne A.C., and Klitgaard H. ucb 34714, a new pyrrolidone derivative: comparison with levetiracetam in hippocampal slice epilepsy models in vitro. Epilepsia 44 suppl 9 (2003) 261
-
(2003)
Epilepsia
, vol.44
, Issue.SUPPL. 9
, pp. 261
-
-
Margineanu, D.-G.1
Kenda, B.M.2
Michel, P.3
Matagne, A.C.4
Klitgaard, H.5
-
6
-
-
0033800837
-
Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs
-
Margineanu D.-G., and Klitgaard H. Inhibition of neuronal hypersynchrony in vitro differentiates levetiracetam from classical antiepileptic drugs. Pharmacol Res 42 (2000) 281-285
-
(2000)
Pharmacol Res
, vol.42
, pp. 281-285
-
-
Margineanu, D.-G.1
Klitgaard, H.2
-
7
-
-
4644273656
-
2003. ucb 34714, a new pyrrolidone derivative: comparison with levetiracetam in animal models of chronic epilepsy in vivo
-
Matagne A.C., Kenda B.M., Michel P., and Klitgaard H. 2003. ucb 34714, a new pyrrolidone derivative: comparison with levetiracetam in animal models of chronic epilepsy in vivo. Epilepsia 44 suppl 9 (2003) 260
-
(2003)
Epilepsia
, vol.44
, Issue.SUPPL. 9
, pp. 260
-
-
Matagne, A.C.1
Kenda, B.M.2
Michel, P.3
Klitgaard, H.4
-
8
-
-
0032504637
-
1998. Self-sustaining status epilepticus after brief electrical stimulation of the perforant path
-
Mazarati A.M., Wasterlain C.G., Sankar R., and Shin D. 1998. Self-sustaining status epilepticus after brief electrical stimulation of the perforant path. Brain Res 801 (1998) 251-253
-
(1998)
Brain Res
, vol.801
, pp. 251-253
-
-
Mazarati, A.M.1
Wasterlain, C.G.2
Sankar, R.3
Shin, D.4
-
9
-
-
0032517750
-
Time-dependent decrease in the effectiveness of antiepileptic drugs during the course of self-sustaining status epilepticus
-
Mazarati A.M., Baldwin R.A., Sankar R., and Wasterlain C.G. Time-dependent decrease in the effectiveness of antiepileptic drugs during the course of self-sustaining status epilepticus. Brain Res 14 (1998) 179-185
-
(1998)
Brain Res
, vol.14
, pp. 179-185
-
-
Mazarati, A.M.1
Baldwin, R.A.2
Sankar, R.3
Wasterlain, C.G.4
-
10
-
-
33745288007
-
Brivaracetam is a potent anticonvulsant in experimental status epilepticus
-
Wasterlain C.G., Suchomelova L., Matagne A.C., Klitgaard H., Mazarati A.M., Shinmei S., et al. Brivaracetam is a potent anticonvulsant in experimental status epilepticus. Epilepsia 46 suppl 8 (2005) 219
-
(2005)
Epilepsia
, vol.46
, Issue.SUPPL. 8
, pp. 219
-
-
Wasterlain, C.G.1
Suchomelova, L.2
Matagne, A.C.3
Klitgaard, H.4
Mazarati, A.M.5
Shinmei, S.6
-
11
-
-
21344470757
-
Ucb 34714: single and multiple rising dose safety, tolerability, and pharmacokinetics in healthy subjects
-
Rolan P., Pigeolet E., and Stockis A. Ucb 34714: single and multiple rising dose safety, tolerability, and pharmacokinetics in healthy subjects. Epilepsia 45 suppl 7 (2004) 314-315
-
(2004)
Epilepsia
, vol.45
, Issue.SUPPL. 7
, pp. 314-315
-
-
Rolan, P.1
Pigeolet, E.2
Stockis, A.3
-
12
-
-
33846245406
-
Brivaracetam safety, tolerability, pharmacokinetics and CNS pharmacodynamic effects after 10 to 1400 mg single rising oral doses in healthy males
-
(in press)
-
Sargentini-Maier M.L., Rolan P., Connell J., et al. Brivaracetam safety, tolerability, pharmacokinetics and CNS pharmacodynamic effects after 10 to 1400 mg single rising oral doses in healthy males. Br J Clin Pharmacol (2006) (in press)
-
(2006)
Br J Clin Pharmacol
-
-
Sargentini-Maier, M.L.1
Rolan, P.2
Connell, J.3
-
13
-
-
0031785952
-
Carbamazepine-10,11-Epoxide in Therapeutic Drug Monitoring
-
Potter J.M., and Donnelly A. Carbamazepine-10,11-Epoxide in Therapeutic Drug Monitoring. Ther Drug Monit 20 (1998) 652-657
-
(1998)
Ther Drug Monit
, vol.20
, pp. 652-657
-
-
Potter, J.M.1
Donnelly, A.2
-
14
-
-
14944357363
-
Proof of principle in the new AED ucb 34714: use of the photosensitivity model
-
Kasteleijn-Nolst Trenité D.G.A., Parain D., Masnou P., Genton P., Steinhoff J., and Hirsch E. Proof of principle in the new AED ucb 34714: use of the photosensitivity model. Epilepsia 45 suppl 7 (2004) 309
-
(2004)
Epilepsia
, vol.45
, Issue.SUPPL. 7
, pp. 309
-
-
Kasteleijn-Nolst Trenité, D.G.A.1
Parain, D.2
Masnou, P.3
Genton, P.4
Steinhoff, J.5
Hirsch, E.6
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