What do we know about alteration in the osteoblast phenotype with microgravity?

Journal of Musculoskeletal Neuronal Interactions

Volumn 6, Issue 4, 2006, Pages 317-318

  Vico, Laurence ^a  

^a UNIVERSITÉ JEAN MONNET   (France)

Author keywords

Cytoskeleton; Extracellular matrix; Focal contacts; Mechanotransduction

Indexed keywords

CYTOKINE; GROWTH FACTOR; INTEGRIN; ION; MYOSIN; MYOSIN II; RAC PROTEIN; RHO FACTOR;

ACTIN FILAMENT; ARTICLE; BIOMECHANICS; BONE MATRIX; CAPILLARY; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL GROWTH; CELL POLARITY; CELL PROLIFERATION; CELL SHAPE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CYTOSKELETON; ENVIRONMENTAL FACTOR; EXTRACELLULAR MATRIX; INTRACELLULAR SPACE; MICROGRAVITY; OSTEOBLAST; OSTEOCYTE; OSTEOLYSIS; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; CELL ADHESION; CELL SHAPE; CELLS, CULTURED; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMANS; MECHANOTRANSDUCTION, CELLULAR; OSTEOBLASTS; PHENOTYPE; SIGNAL TRANSDUCTION; WEIGHTLESSNESS;

EID: 33846198265     PISSN: 11087161     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Cowin SC. On mechanosensation in bone under micro-gravity. Bone 1998; 22(Suppl.5):119S-125S.
2. Hughes-Fulford M. Physiological effects of microgravity on osteoblast morphology and cell biology. Adv Space Biol Med 2002; 8:129-157.
3. Marie PJ, Jones D, Vico L, Zallone A, Hinsenkamp M, Cancedda R. Osteobiology, strain, and microgravity: part I. Studies at the cellular level. Calcif Tissue Int 2000; 67:2-9. Erratum in: Calcif Tissue Int 2001; 68:61-62.
4. Carmeliet G. Bouillon R. The effect of microgravity on morphology and gene expression of osteoblasts in vitro. FASEB J 1999; 13(Suppl.):SI29-34.
5. Burger EH, Klein-Nulend J. Microgravity and bone cell mechanosensitivity. Bone 1998; 22(Suppl.5):127S-130S.