Expression of haematopoietic stem cell markers, CD133 and CD34 on human corneal keratocytes

British Journal of Ophthalmology

Volumn 91, Issue 1, 2007, Pages 94-99

  Perrella, G ^a   Brusini, P ^b   Spelat, R ^a   Hossain, P ^c   Hopkinson, A ^d   Dua, H S ^d  

^a UNIVERSITY OF UDINE   (Italy)

^b UNIVERSITY HOSPITAL OF UDINE   (Italy)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD34 ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CADAVER DONOR; CELL CULTURE; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; CELL SELECTION; CORNEA CELL; CORNEA STROMA; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; HUMAN; PRIORITY JOURNAL; WESTERN BLOTTING;

ANTIBODIES; ANTIGENS, CD; ANTIGENS, CD34; BIOLOGICAL MARKERS; CADAVER; CELL PROLIFERATION; CELLS, CULTURED; CORNEA; FLOW CYTOMETRY; GLYCOPROTEINS; HEMATOPOIETIC STEM CELLS; HUMANS; PEPTIDES; STROMAL CELLS;

EID: 33846187554     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2006.097352     Document Type: Article

References (26)

1. Ueda A, Nishida T, Otori T, et al. Electron-microscopic studies on the presence of gap junctions between corneal fibroblasts in rabbits. Cell Tissue Res 1987;249:473-5.
2. Jester JV, Barry PA, Lind GJ, et al. Corneal keratocytes: in situ and in vitro organization of cytoskeletal contractile proteins. Invest Ophthalmol Vis Sci 1994;35:730-43.
3. Muller U, Pels L, Vrensen GF. Novel aspects of the ultrastructural organization of human corneal keratocytes. Invest Ophthalmol Vis Sci 1995;36:2557-67.
4. Hossain PN, Jham S, Joseph A, et al. Human keratocytes express high levels of CD34 in situ (ARVO abstract). Invest Ophthalmol Vis Sc 2001;42(S1-945):B230 (abstract 3088).
5. Joseph A, Hossain P, Seema J, et al. Expression of CD34 and L-selectin on human corneal keratocytes. Invest Ophthalmol Vis Sci 2003;44:4689-92.
6. Toti P, Tosi GM, Traversi C, et al. CD-34 stromal expression pattern in normal and altered human corneas. Ophthalmology 2002;109:1167-71.
7. Krause DS, Fackler MJ, Civin CI, et al. CD34: structure, biology, and clinical utility. Blood 1996;87:1-13.
8. Bhatia M. AC133 expression in human stem cells. Leukemia 2001;15:1685-8.
9. Corbeil D, Roper K, Hellwig A, et al. The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J Biol Chem 2000;275: 5512-20.
10. Yin AH, Miraglia S, Zanjani ED, et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997;90:5002-12.
11. Yu Y, Flint A, Dvorin EL, et al. AC133-2, a novel isoform of human AC133 stem cell antigen. J Biol Chem 2002;277:20711-16.
12. Greaves MF, Brown J, Molgoard HV, et al. Molecular features of CD34: a hemopoielic progenitor cell-associated molecule. Leukemia 1992;6(Suppl 1):31-6.
13. Ambesi-Impiombato FS, Parks AAM, Coon HG. Culture of hormone-dependent functional epithelia cell a from rat thyroid. Proc Natl Acad Sci USA 1980;77:3455-59.
14. Coon HG. Clonal stability and phenotypic expression of chick cartilage cells in vitro. Proc Natl Acad Sci USA 1966;55:66-73.
15. Curcio F, Ambesi-Impiombato FS, Perrella G, et al. Long-term culture and functional characterization of follicular cells from adult normal human thyroids. Proc Natl Acad Sci USA 1994;91:9004-8.
16. Gallacher L, Murdoch B, Wu DM, et al. Isolation and characterization of human CD34Lin and CD34+Lin hematopoietic stem cells using cell surface markers AC133 and CD7. Blood 2000;95:2813-20.
17. Gehling UM, Ergün S, Schumacher U, et al. In vitro differentiation of endothelial cells from AC133-positive progenitor cells. Blood 2000;95:3106-12.
18. Horn PA, Tesch H, Staib P, et al. Expression of AC133, a novel hematopoietic precursor antigen, on acute myeloid leukemia cells. Blood 1999;93:1435-7.
19. Bühring H, Seiffert M, Marxer A, et al. AC133 antigen expression is not restricted to acute myeloid leukemia blasts but is also found on acute lymphoid leukemia blasts and on a subset of CD34+ B-cell precursors. Blood 1999;94:832-3.
20. de Wynter EA, Buck D, Hart C, et al. CD34+AC133+ cells isolated from cord blood are highly enriched in long-term culture-initiating cells, NOD/SCID-repopulating cells and dendritic cell progenitors. Stem Cells 1998;16:387-96.
21. Rodrigo B, Rainer F, Blundell PA, et al. Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ. Nature 1987;326:515- 17.
22. Silverman JS, Tamsen A. Fibrohistiocytic differentiation in subcutaneous fatty tumours. Study of spindle cell, pleomorphic, myxoid, and atypical lipoma and differentiated liposarcoma cases composed in part of CD34+ firbroblasts and FXIIIa+ histocytes. J Cutan Pathol 1997;24:484- 93.
23. Jester JV, Rodrigues MM, Herman IM. Characterization of avascular corneal wound healing ribroblasts. New insights into the myofibroblast. Am J Pathol 1987;127:140-8.
24. Maltseva O, Folger P, Zekaria D, et al. Fibroblast growth factor reversal of the corneal myofibroblast phenotype. Invest Ophthalmol Vis Sci 2001;42:2490-5.
25. Jester JV, Huang J, Barry-Lane PA, et al. Transforming growth factor(beta)-mediated corneal myofibroblast differentiation requires actin and fibronecfin assembly. Invest Ophthalmol Vis Sci 1999;40:1959-67.
26. Sosnova M, Bradl M, Forrester JV. CD34+ corneal stromal cells are bone marrow-derived and express hemopoietic stem cell markers. Stem Cells 2005;23:507-15.