Alterations in Purinoceptor Expression in Human Long Saphenous Vein during Varicose Disease

European Journal of Vascular and Endovascular Surgery

Volumn 33, Issue 2, 2007, Pages 239-250

  Metcalfe, M J ^a,b   Baker, D M ^b   Turmaine, M ^c   Burnstock, G ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b ROYAL FREE HOSPITAL   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Human; P2X receptor; P2Y receptor; Phenotype; Saphenous vein

Indexed keywords

PURINE P2X1 RECEPTOR; PURINE P2Y1 RECEPTOR; PURINE P2Y2 RECEPTOR; PURINE P2Y4 RECEPTOR; PURINE P2Y6 RECEPTOR;

ADULT; AGED; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEG VARICOSIS; MALE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; SAPHENOUS VEIN; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE FIBER; VEIN WALL;

ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, ELECTRON; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, PURINERGIC; SAPHENOUS VEIN; VARICOSE VEINS; VASOCONSTRICTION;

EID: 33846145058     PISSN: 10785884     EISSN: 15322165     Source Type: Journal    
DOI: 10.1016/j.ejvs.2006.09.007     Document Type: Article

References (46)

1. Lees T.A., and Redwood N.F.W. Chronic venous insufficiency and lymphoedema. In: Beard J.D., and Gaines P.A. (Eds). Vascular and Endovascular Surgery (2001), W.B. Saunders, Philadelphia 451-482
2. Burnstock G. Integration of factors controlling vascular tone. Overview. Anesthesiology 79 (1993) 1368-1380
3. Badier-Commander C., Couvelard A., Henin D., Verbeuren T., Michel J.-B., and Jacob M.-P. Smooth muscle cell modulation and cytokine overproduction in varicose veins. An in situ study. J Pathol 193 (2001) 398-407
4. Wali M.A., and Eid R.A. Smooth muscle changes in varicose veins: an ultrastructural study. J Smooth Muscle Res 37 (2001) 123-135
5. Rose S.S., and Ahmed A. Some thoughts on the aetiology of varicose veins. J Cardiovasc Surg (Torino) 27 (1986) 534-543
6. Lowell R.C., Gloviczki P., and Miller V.M. In vitro evaluation of endothelial and smooth muscle function of primary varicose veins. J Vasc Surg 16 (1992) 679-686
7. Ralevic V., and Burnstock G. Involvement of purinergic signaling in cardiovascular diseases. Drug News Perspect 16 (2003) 133-140
8. Burnstock G. Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol 22 (2002) 364-373
9. Ralevic V., and Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev 50 (1998) 413-492
10. 14 receptor) adds diversity to the P2Y receptor family. Trends Pharmacol Sci 24 (2003) 52-55
11. Burnstock G. Introduction: P2 receptors. Curr Top Med Chem 4 (2004) 793-803
12. 12 receptor as a therapeutic target in cardiovascular disease. Platelets 12 (2001) 197-209
13. Rankin A.C., Brooks R., Ruskin J.N., and McGovern B.A. Adenosine and the treatment of supraventricular tachycardia. Am J Med 92 (1992) 655-664
14. Racchi H., Irarrázabal M.J., Howard M., Morán S., Zalaquett R., and Huidobro-Toro P. Adenosine 5′-triphosphate and neuropeptide Y are co-transmitters in conjunction with noradrenaline in the human saphenous vein. Br J Pharmacol 126 (1999) 1175-1185
15. Rump L.C., and von Kügelgen I. A study of ATP as a sympathetic cotransmitter in human saphenous vein. Br J Pharmacol 111 (1994) 65-72
16. Ziganshin A.U., Khaziakhmetov D.F., Ziganshina L.E., Khaziakhmetova V.N., Jourjikiya R.K., Ziganshin B.A., et al. Varicose disease affects the P2 receptor-mediated responses of human greater saphenous vein. Vascul Pharmacol 42 (2005) 17-21
17. Marin M.L., Gordon R.E., Veith F.J., Panetta T.F., Sales C.M., and Wengerter K.R. Human greater saphenous vein: histologic and ultrastructural variation. Cardiovasc Surg 2 (1994) 56-62
18. Ciardullo A.V., Panico S., Bellati C., Rubba P., Rinaldi S., and Iannuzzi A. High endogenous estradiol is associated with increased venous distensibility and clinical evidence of varicose veins in menopausal women. J Vasc Surg 32 (2000) 544-549
19. Mashiah A., Berman V., Thole H.H., Rose S.S., Pasik S., Schwarz H., et al. Estrogen and progesterone receptors in normal and varicose saphenous veins. Cardiovasc Surg 7 (1999) 327-331
20. Haynes J.M., Pennefather J.N., and Sikorski B. Purinoceptor-mediated contractility of the perfused uterine vasculature of the guinea-pig: influence of oestradiol and pregnancy. Clin Exp Pharmacol Physiol 30 (2003) 329-335
21. Khan A.A., Eid R.A., and Hamdi A. Structural changes in the tunica intima of varicose veins: a histopathological and ultrastructural study. Pathology 32 (2000) 253-257
22. Uvelius B., Arner A., and Johansson B. Structural and mechanical alterations in hypertrophic venous smooth muscle. Acta Physiol Scand 112 (1981) 463-471
23. Arnould T., Michiels C., Janssens D., Berna N., and Remacle J. Effect of Ginkor Fort on hypoxia-induced neutrophil adherence to human saphenous vein endothelium. J Cardiovasc Pharmacol 31 (1998) 456-463
24. Kohler T.R., Kirkman T.R., Kraiss L.W., Zierler B.K., and Clowes A.W. Increased blood flow inhibits neointimal hyperplasia in endothelialized vascular grafts. Circ Res 69 (1991) 1557-1565
25. Lee K.M., Tsai K.Y., Wang N., and Ingber D.E. Extracellular matrix and pulmonary hypertension: control of vascular smooth muscle cell contractility. Am J Physiol 274 (1998) H76-H82
26. Travers J.P., Brookes C.E., Evans J., Baker D.M., Kent C., and Makin G.S.A. Assessment of wall structure and composition of varicose veins with reference to collagen, elastin and smooth muscle content. Eur J Vasc Endovasc Surg 11 (1996) 230-237
27. Buján J., Gimeno M.J., Jiménez J.A., Kielty C.M., Mecham R.P., and Bellón J.M. Expression of elastic components in healthy and varicose veins. World J Surg 27 (2003) 901-905
28. Rizzi A., Quaglio D., Vasquez G., Mascoli F., Amadesi S., and Calo G. Effects of vasoactive agents in healthy and diseased human saphenous veins. J Vasc Surg 28 (1998) 855-861
29. 2 receptors on cultured human saphenous vein endothelial cells. J Vasc Res 37 (2000) 548-555
30. Borna C., Wang L., Gudbjartsson T., Karlsson L., Jern S., and Malmsjö M. Contractions in human coronary bypass vessels stimulated by extracellular nucleotides. Ann Thorac Surg 76 (2003) 50-57
31. Kawasaki K., Iino T., Hasegawa H., Miyazawa I., and Hosoda S. The function of intimal longitudinal smooth muscles of the human coronary artery. Experientia 42 (1986) 1222-1224
32. Kennedy C., and Burnstock G. Evidence for two types of P2-purinoceptor in longitudinal muscle of the rabbit portal vein. Eur J Pharmacol 111 (1985) 49-56
33. Gibbons G.H. Autocrine-paracrine factors and vascular remodeling in hypertension. Curr Opin Nephrol Hypertens 2 (1993) 291-298
34. Schachter M. Endothelium and smooth muscle: trophic interactions and potential for therapeutic intervention. J Hum Hypertens 4 Suppl. 4 (1990) 17-20
35. Erlinge D. Extracellular ATP: a growth factor for vascular smooth muscle cells. Gen Pharmacol 31 (1998) 1-8
36. Ralevic V., and Burnstock G. Roles of P2-purinoceptors in the cardiovascular system. Circulation 84 (1991) 1-14
37. Thyberg J. Differentiated properties and proliferation of arterial smooth muscle cells in culture. Int Rev Cytol 169 (1996) 183-265
38. Erlinge D., Hou M., Webb T.E., Barnard E.A., and Moller S. Phenotype changes of the vascular smooth muscle cell regulate P2 receptor expression as measured by quantitative RT-PCR. Biochem Biophys Res Commun 248 (1998) 864-870
39. 6 receptors. Am J Physiol Heart Circ Physiol 282 (2002) H784-H792
40. 4 nucleotide receptors are involved in the regulation of rat aortic smooth muscle cells by UTP and ATP. Br J Pharmacol 124 (1998) 703-710
41. Schuller-Petrovic S., Siedler S., Kern T., Meinhart J., Schmidt K., and Brunner F. Imbalance between the endothelial cell-derived contracting factors prostacyclin and angiotensin II and nitric oxide/cyclic GMP in human primary varicosis. Br J Pharmacol 122 (1997) 772-778
42. Dubey R.K., Gillespie D.G., and Jackson E.K. Adenosine inhibits collagen and total protein synthesis in vascular smooth muscle cells. Hypertension 33 (1999) 190-194
43. Wang D.J., Huang N.N., and Heppel L.A. Extracellular ATP and ADP stimulate proliferation of porcine aortic smooth muscle cells. J Cell Physiol 153 (1992) 221-233
44. Sarjeant J.M., and Rabinovitch M. Understanding and treating vein graft atherosclerosis. Cardiovasc Pathol 11 (2002) 263-271
45. Burnstock G. Noradrenaline and ATP as cotransmitters in sympathetic nerves. Neurochem Int 17 (1990) 357-368
46. Burnstock G. Release of vasoactive substances from endothelial cells by shear stress and purinergic mechanosensory transduction. J Anat 194 (1999) 335-342