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Volumn 37, Issue 3, 2006, Pages 405-413

The hormone replacement therapy drug tibolone acts very similar to medroxyprogesterone acetate in an estrogen- and progesterone-responsive endometrial cancer cell line

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; ESTROGEN RECEPTOR; MEDROXYPROGESTERONE ACETATE; MINICHROMOSOME MAINTENANCE PROTEIN; PROGESTERONE RECEPTOR; TIBOLONE;

EID: 33846142848     PISSN: 09525041     EISSN: None     Source Type: Journal    
DOI: 10.1677/jme.1.02057     Document Type: Article
Times cited : (8)

References (22)
  • 3
    • 18144421167 scopus 로고    scopus 로고
    • Endometrial cancer and hormone-replacement therapy in the million women studx
    • Beral V, Bull D & Reeves G 2005 Endometrial cancer and hormone-replacement therapy in the million women studx. Lancet 365 1543-1551.
    • (2005) Lancet , vol.365 , pp. 1543-1551
    • Beral, V.1    Bull, D.2    Reeves, G.3
  • 4
    • 0028812689 scopus 로고
    • Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation
    • Blok LJ, Grossmann ME, Perry JE & Tindall DJ 1995 Characterization of an early growth response gene, which encodes a zinc finger transcription factor, potentially involved in cell cycle regulation. Molecular Endocrinology 9 1610-1620.
    • (1995) Molecular Endocrinology , vol.9 , pp. 1610-1620
    • Blok, L.J.1    Grossmann, M.E.2    Perry, J.E.3    Tindall, D.J.4
  • 5
    • 0037316303 scopus 로고    scopus 로고
    • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
    • Bolstad BM, Irizarry RA, Astrand M & Speed TP 2003 A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19 185-193.
    • (2003) Bioinformatics , vol.19 , pp. 185-193
    • Bolstad, B.M.1    Irizarry, R.A.2    Astrand, M.3    Speed, T.P.4
  • 6
    • 0037333156 scopus 로고    scopus 로고
    • Tibolone is not converted by human aromatase to 7alpha-nethyl-17alpha-ethynylestradiol (7alpha-MEE): Analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS
    • de Gooyer ME, Oppers-Tiemissen HM, Leysen D, Verheul HA & Kloosterbper HJ 2003 Tibolone is not converted by human aromatase to 7alpha-nethyl-17alpha-ethynylestradiol (7alpha-MEE): analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS. Steroids 68 235-243.
    • (2003) Steroids , vol.68 , pp. 235-243
    • de Gooyer, M.E.1    Oppers-Tiemissen, H.M.2    Leysen, D.3    Verheul, H.A.4    Kloosterbper, H.J.5
  • 10
    • 0141792846 scopus 로고    scopus 로고
    • Expression of replication-licensing factors MCM2 and MCM3 in normal, hyperplastic, and carcinomatous endometrium: Correlation with expression of Ki-67 and estrogen and progesterone receptors
    • Kato K, Toki T, Shimizu M, Shiozawa T, Fujii S, Nikaido T & Konishi I 2003 Expression of replication-licensing factors MCM2 and MCM3 in normal, hyperplastic, and carcinomatous endometrium: correlation with expression of Ki-67 and estrogen and progesterone receptors. International Journal of Gynecological Pathology 22 334-340.
    • (2003) International Journal of Gynecological Pathology , vol.22 , pp. 334-340
    • Kato, K.1    Toki, T.2    Shimizu, M.3    Shiozawa, T.4    Fujii, S.5    Nikaido, T.6    Konishi, I.7
  • 13
    • 0025359604 scopus 로고
    • In vitro evaluation of estrogenic, estrogen antagonistic and progestagenic effects of a steroidal drug (Org OD-14) and its metabolites on human endometrium
    • Markiewicz L & Gurpide E 1990 In vitro evaluation of estrogenic, estrogen antagonistic and progestagenic effects of a steroidal drug (Org OD-14) and its metabolites on human endometrium. Journal of Steroid Biochemistry and Molecular Biology 35 535-541.
    • (1990) Journal of Steroid Biochemistry and Molecular Biology , vol.35 , pp. 535-541
    • Markiewicz, L.1    Gurpide, E.2
  • 14
    • 0020658509 scopus 로고
    • Human endometrial adenocarcinoma transplanted into nude mice: Growth regulation by estradiol
    • Satvaswaroop PG, Zaino RJ & Mortel R 1983 Human endometrial adenocarcinoma transplanted into nude mice: growth regulation by estradiol. Science 219 58-60.
    • (1983) Science , vol.219 , pp. 58-60
    • Satvaswaroop, P.G.1    Zaino, R.J.2    Mortel, R.3
  • 15
    • 24944522450 scopus 로고    scopus 로고
    • Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: Evidence of progestagenic effects
    • Schatz F, Kuczynski E, Kloosterboer HJ, Buchwalder L, Tang C, Krikun G & Lockwood CJ 2005 Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: evidence of progestagenic effects. Steroids 70 840-845.
    • (2005) Steroids , vol.70 , pp. 840-845
    • Schatz, F.1    Kuczynski, E.2    Kloosterboer, H.J.3    Buchwalder, L.4    Tang, C.5    Krikun, G.6    Lockwood, C.J.7
  • 17
    • 9644287713 scopus 로고    scopus 로고
    • Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: Inversion of stereospecificity with a delta5(10)-3-ketosteroid
    • Steckelbroeck S, Jin Y, Oyesanmi B, Kloosterboer HJ & Penning TM 2004 Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: inversion of stereospecificity with a delta5(10)-3-ketosteroid. Molecular Pharmacology 66 1702-1711.
    • (2004) Molecular Pharmacology , vol.66 , pp. 1702-1711
    • Steckelbroeck, S.1    Jin, Y.2    Oyesanmi, B.3    Kloosterboer, H.J.4    Penning, T.M.5
  • 18
    • 0027216228 scopus 로고
    • Human endometrial 3 beta-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic/progestagenic activity ratios of a steroidal drug (Org OD 14)
    • Tang B, Markiewicz L, Kloosterboer HJ & Gurpide E 1993 Human endometrial 3 beta-hydroxysteroid dehydrogenase/isomerase can locally reduce intrinsic estrogenic/progestagenic activity ratios of a steroidal drug (Org OD 14). Journal of Steroid Biochemistry and Molecular Biology 45 345-351.
    • (1993) Journal of Steroid Biochemistry and Molecular Biology , vol.45 , pp. 345-351
    • Tang, B.1    Markiewicz, L.2    Kloosterboer, H.J.3    Gurpide, E.4
  • 19
    • 0034002645 scopus 로고    scopus 로고
    • Immunolocalisation of oestrogen receptor beta in human tissues
    • Taylor AH & Al-Azzawi F 2000 Immunolocalisation of oestrogen receptor beta in human tissues. Journal of Molecular Endocrinology 24 145-155.
    • (2000) Journal of Molecular Endocrinology , vol.24 , pp. 145-155
    • Taylor, A.H.1    Al-Azzawi, F.2
  • 20
    • 0036140161 scopus 로고    scopus 로고
    • Dose proportionality of three different doses of tibolone
    • Timmer CJ & Houwing NS 2002 Dose proportionality of three different doses of tibolone. Pharmacotherapy 22 6.
    • (2002) Pharmacotherapy , vol.22 , pp. 6
    • Timmer, C.J.1    Houwing, N.S.2
  • 21
    • 0016786289 scopus 로고
    • Induction of human endometrial estradiol dehydrogenase by progestins
    • Tseng L & Gurpide E 1975 Induction of human endometrial estradiol dehydrogenase by progestins. Endocrinology 97 825-833.
    • (1975) Endocrinology , vol.97 , pp. 825-833
    • Tseng, L.1    Gurpide, E.2
  • 22
    • 0037452888 scopus 로고    scopus 로고
    • Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci
    • Zhang H, Pan KH & Cohen SN 2003 Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci. PNAS 100 3251-3256.
    • (2003) PNAS , vol.100 , pp. 3251-3256
    • Zhang, H.1    Pan, K.H.2    Cohen, S.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.