Stop! In the name of transforming growth factor-β: Keeping estrogen receptor-α-positive mammary epithelial cells from proliferating

Breast Cancer Research

Volumn 8, Issue 4, 2006, Pages

  Grimm, Sandra L ^a   Rosen, Jeffrey M ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA;

ALLELE; ARTICLE; AUTOCRINE EFFECT; BREAST CANCER; BREAST EPITHELIUM; CANCER GROWTH; CELL PROLIFERATION; DISEASE MODEL; EPITHELIUM CELL; HUMAN; MAMMARY GLAND; PARACRINE SIGNALING; PROGNOSIS; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; BOVINAE; BREAST; CYTOLOGY; FEMALE; METABOLISM; MOUSE; PHYSIOLOGY; RAT; UDDER;

ANIMALS; BREAST; CATTLE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; ESTROGEN RECEPTOR ALPHA; FEMALE; HUMANS; MAMMARY GLANDS, ANIMAL; MICE; RATS; TRANSFORMING GROWTH FACTOR BETA;

EID: 33846107166     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr1520     Document Type: Article

References (21)

1. Ewan KB, Oketch-Rabah HA, Ravani SA, Shyamala G, Moses HL, Barcellos-Hoff MH: Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor β1 in adult mice. Am J Pathol 2005, 167: 409-417.
2. Ewan KB, Shyamala G, Revani SA, Tang Y, Akhurat R, Wakefield L, Barcellos-Hoff MH: Latent transforming growth factor-beta activation in mammary gland: Regulation by ovarian hormones affects ductal and alveolar proliferation. Am J Pathol 2002, 160:2081-2093
3. Clarke RB, Howell A, Potten CS, Anderson E: Dissociation between steroid receptor erpression and cell proliferatoin in the human breast. Cancer Res 1997, 57:4987-4991.
4. Russo J, Ao X, Grill C, Russo IH: Pattern of distribution of cells positive for estrogen receptor alpha and progesterone receptor in relation to proliferating cells in the mammary gland. Breast Cancer Res Treat 1999, 53:217-227.
5. Seagroves TN, Lydon JP, Hovey RC, Vonderhaar BK, Rosen JM: C/EBPβ (CCAAT/enhancer binding protein) controls call fate determination during mammary gland development. Mol Endocrinol 2000, 14;359-368.
6. Capuco AV, Ellis S, Wood DL, Akers RM, Garrett W: Postnatal mammary ductal growth: Three-dimensional Imaging of cell proliferation, effects of estrogen treatment and expression of steriod receptors in prepubertal calves. Tissue Cell 2002, 34: 143-154.
7. Brisken C, Park S, Vass T, Lydon JP, O'Malley BW, Weinberg RA: A paracrine role for the epithelial progesterone receptor in mammary gland development. Proc Natl Acad Sci USA 1998, 95:5076-5081.
8. Mallepell S, Krust A, Chambon P, Brisken C: Paracrine, signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in this mammary gland. Proc Natl Acad Sci USA 2006, 103:2196-2201.
9. Medina D, Kittrell FS, Shepard A, Stephens LC, Jiang C, Lu J, Allred DC, McCarthy M, Ullrich RL: Biological and genetic properties of the p53 null prenetroplastic mammary epithelium. FASEB J 2002, 16:881-883.
10. Shoker BS, Jarvis C, Clarke RB, Anderson E, Hewlett J, Davies MP, Sibson DR, Sloane JP: Estrogen receptor-positive proliferating cells in the normal and precancerous breast. Am J Pathol 1999, 10:1811-1815.
11. Bercellosa-Hoff MH: Latency and activation in the control of TGF-β. J Mammary Gland Biol Neoplasia 1998, 1:353-363.
12. Tang B, Bottinger EP, Jakowlew SB, Bagnall KM, Mariano J, Anver MR, Letterio JJ, Wakefield LM: Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency. Nat Med 1998, 4:802-807.
13. Medina D, Sivaraman L, Hilsenbeck SG, Conneely O, Ginger M, Rosen J, Omelle BW: Mechanisms of hormonal prevention of breast cancer. Ann NY Acad Sci 2001, 952:23-35.
14. Boulanger CA, Wagner KU, Smith GH: Parity-Induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-β1 expression. Oncogene 2005, 24:552-560.
15. Boulanger CA, Smith GH: Reducing mammary cancer risk through premature stem cell senescence. Oncogene 2001, 20:2264-2272.
16. Grimm SL, Contreras A, Barcellos-Hoff MH, Rosen JM: Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPβ)-null mice. J Biol Chem 2005, 280:30301-36309.
17. Polyak K. Kato JY, Solomon MJ, Sherr CJ, Massague J, Roberts JM, Koff A: p27Kip1, a cyclin-Cdk Inhibitor, links transforming growth factor-beta and contract inhibition by cell cycle arrest. Genes Dev 1994, 8:9-22.
18. Forster JS, Hanley DC, Bukovsky A, Seth P, Wimalasena J: Multi-faceted regulation of cell cycle, progression by estrogen regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function. Mol Cell Biol 2001, 21:794-810.
19. Lee WR, Chen CC, Liu S, Safe S: 17β-estradiol (E2) induces cdc25A gene expression in breast cancer cells by genomic and non-genomic pathways. J Cell Biochem, in press.
20. Ray D, Terao Y, Nimbalkar D, Chu LH, Donzelli M, Tsutsui T, Zou X, Ghosh AK, Varga J, Draetta GF, et al. Transforming growth factor β facilitates β-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner. Mol Cell Biol 2005, 25:3338-3347.
21. Alkarain A, Jordan R, Slingerland J: P27 deregulation in breast, cancer: prognostic significance and Implications for therapy, J Mammary Gland Biol Neoplasm 2004, 9:67-80