Evidence that moxidectin is a greater risk factor than ivermectin in the development of resistance to macrocyclic lactones by ostertagia spp in sheep in South Eastern Australia

New Zealand Veterinary Journal

Volumn 54, Issue 6, 2006, Pages 313-317

  Rendell, D K ^a   Rentsch, T E ^a   Smith, J M ^a   Chandler, D S ^b   Callinan, A P L ^c  

^a David Rendell Associates   (Australia)

^b Argenta Manufacturing Limited   (New Zealand)

^c Bendigo Scientific Data Analysts   (Australia)

Author keywords

Anthelmintic resistance; Ivermectin; Macrocyclic lactone; Moxidectin; Ostertagia; Sheep; Southeast Australia

Indexed keywords

ANTHELMINTIC AGENT; IVERMECTIN; MACROLIDE; MILBEMYCIN;

ANIMAL; ANIMAL DISEASE; ANIMAL HUSBANDRY; ARTICLE; AUSTRALIA; DRUG COMBINATION; DRUG EFFECT; DRUG RESISTANCE; DRUG SENSITIVITY; FECES; FEMALE; MALE; METHODOLOGY; ORAL DRUG ADMINISTRATION; OSTERTAGIA; PARASITE IDENTIFICATION; PARASITOLOGY; PREVALENCE; RANDOMIZATION; RISK FACTOR; SHEEP; SHEEP DISEASE; TREATMENT OUTCOME; TRICHOSTRONGYLOSIS;

ADMINISTRATION, ORAL; ANIMAL HUSBANDRY; ANIMALS; ANTHELMINTICS; AUSTRALIA; DRUG RESISTANCE; DRUG THERAPY, COMBINATION; FECES; FEMALE; IVERMECTIN; MACROLIDES; MALE; OSTERTAGIA; OSTERTAGIASIS; PARASITE EGG COUNT; PARASITIC SENSITIVITY TESTS; PREVALENCE; RANDOM ALLOCATION; RISK FACTORS; SHEEP; SHEEP DISEASES; TREATMENT OUTCOME; VICTORIA;

OSTERTAGIA; OVIS ARIES; TELADORSAGIA;

EID: 33846055348     PISSN: 00480169     EISSN: 11760710     Source Type: Journal    
DOI: 10.1080/00480169.2006.36716     Document Type: Article

References (32)

1. Abbott KA, Cobb RM, Glass MH. Duration of the persistent activity of moxidectin against Haemonchus contortus in sheep. Australian Veterinary Journal 72, 408–10, 1995
2. Anonymous. September 2004 Newsletter. Quarterly Telephone Survey of 2,250 Farmers. Hoyle R, Woods R, and Sloane B, Solutions Marketing and Research Farm Panel, Sydney, NSW, Australia, 2004
3. Craig TM, Hatfield TA, Pankavich JA, Wang GT. Efficacy of moxidectin against an ivermectin-resistant strain of Haemonchus contortus in sheep. Veterinary Parasitology 41, 329–33, 1992
4. Dobson RJ, Besier RB. Modelling the impact on anthelmintic resistance of refugia, drug type and drug combinations. Proceedings of the New Zealand Society of Parasitology 32, 23, 2004
5. Dobson RJ, Le Jambre LF, Gill JH. Management of anthelmintic resistance: Inheritance of resistance and selection with persistent drugs. International Journal for Parasitology 26, 993–1000, 1996
6. Dobson RJ, Besier RB, Barnes EH, Love SC, Vizard A, Bell K, Le Jambre LF. Principles for the use of macrocyclic lactones to minimise selection for resistance. Australian Veterinary Journal 79, 756–61, 2001
7. Eddi C, Caracostantogolo J, Pena M, Schapiro J, Marangunich L, Waller PJ, Hansen JW. The prevalence of drench resistance in nematode parasites of sheep in southern Latin America: Argentina. Veterinary Parasitology 62, 189–97, 1996
8. Edwards JR, Wroth R, de Chaneet GC, Besier RB, Karlsson J, Morcombe PW, Dalton-Morgan G, Roberts D. Survey of drench resistance in Western Australian sheep flocks. Relationship with sheep management and parasite control practices. Australian Veterinary Journal 63, 139–44, 1986
9. Imperiale F, Lifschitz A, Sallovitz J, Virkel G, Lanusse C. Comparative depletion of ivermectin and moxidectin milk residues in dairy sheep after oral and subcutaneous administration. Journal of Dairy Research 71, 427–33, 2004
10. Kao RR, Leathwick DM, Roberts MG, Sutherland IA. Nematode parasites of sheep: a survey of epidemiological parameters and their application in a simple model. Parasitology 121, 85–103, 2000
11. Keiran PJ. Moxidectin against ivermectin-resistant nematodes- a global view. Australian Veterinary Journal 71, 18–20, 1994
12. Kotze AC, Dobson RJ, Tyrrell KL, Stein PA. High-level ivermectin resistance in a field isolate of Haemonchus contortus associated with a low level of resistance in the larval stage: implications for resistance detection. Veterinary Parasitology 108, 255–63, 2002
13. Le Jambre LF, Dobson RJ, Lenane IJ, Barnes EH. Selection for anthelmintic resistance by macrocyclic lactones in Haemonchus contortus. International Journal for Parasitology 29, 1101–11, 1999
14. Macchi C, Pomroy WE, Pfeiffer DU. Drench use in sheep; results of a questionnaire. New Zealand Journal of Zoology 26, 70, 1999
15. Molento MB, Wang GT, Prichard RK. Decreased ivermectin and moxidectin sensitivity in Haemonchus contortus selected with moxidectin over 14 generations. Veterinary Parasitology 86, 77–81, 1999
16. Overend DJ, Phillips ML, Poulton AL, Foster CE. Drench resistance in Australian sheep nematode populations. Australian Veterinary Journal 71, 117–21, 1994
17. Ranjan S, Wang GT, Hirschlein C, Simkins KL. Selection for resistance to macrocyclic lactones by Haemonchus contortus in sheep. Veterinary Parasitology 103, 109–17, 2002
18. Rhodes AP, Leathwick DM, Pomroy WE, West DM, Jackson R, Lawrence K, Moffat J, Waghorn TS. A profile of anthelmintic resistance and parasite control practices in New Zealand- results from a 2005 survey. Proceedings of the New Zealand Society of Animal Production 66, 14–19, 2006
19. Sallovitz J, Lifschitz A, Imperiale F, Pis A, Virkel G, Lanusse C. Breed differences on the plasma availability of moxidectin administered pour-on to calves. Veterinary Journal 164, 47–53, 2002
20. Shoop WL, Haines HW, Michael BF, Eary CH. Mutual resistance to avermectin and milbemycins- oral activity of ivermectin and moxidectin against ivermectin-resistant and susceptible nematodes. Veterinary Record 133, 445–7, 1993
21. Shoop WL, Michael BF, Haines HW, Murphy TP, Faidley TD, Hajdu R, Thompson DR. Moxidectin and ivermectin in lambs: plasma depletion and efficacy against helminths. Journal of Veterinary Pharmacology and Therapeutics (Supplement 1), 10–19, 1997
22. Smith G. A mathematical model for the evolution of anthelmintic resistance in a direct life cycle nematode parasite. International Journal for Parasitology 20, 913–21, 1990
23. Stafford K, Coles GC. Nematode control practices and drench resistance in dairy calves in the south west of England. Veterinary Record 144, 659–61, 1999
24. Suter RJ, Besier RB, Perkins NR, Robertson ID, Chapman HM. Sheep farm risk factors for ivermectin resistance in Ostertagia circumcincta in Western Australia. Preventative Veterinary Medicine 63, 257–69, 2004
25. Suter RJ, McKinnon EJ, Perkins NR, Besier RB. Effective life of ivermectin on Western Australian sheep farms- a survival analysis. Preventative Veterinary Medicine 72, 311–5, 2005
26. Sutherland IA, Leathwick DM, Brown AE. Moxidectin: persistence and efficacy against drug-resistant Ostertagia circumcincta. Journal of Veterinary Pharmacology and Therapeutics 22, 2–5, 1999
27. Sutherland IA, Brown AE, Leathwick DM, Bisset SA. Resistance to prophylactic treatment with macrocyclic lactone anthelmintics in Teladorsagia circumcincta. Veterinary Parasitology 115, 301–9, 2003
28. Trengrove CL. How to determine optimum time for the first summer drench. Australian Veterinary Association Conference of the Sheep Veterinary Society 13, 144–50, 2000
29. Tyrrell KL, Dobson RJ, Stein PA, Walkden-Brown SW. The effects of ivermectin and moxidectin on egg viability and larval development of ivermectin-resistant Haemonchus contortus. Veterinary Parasitology 107, 85–93, 2002
30. Vizard AL, Wallace RJ. A simplified faecal egg count reduction test. Australian Veterinary Journal 64, 109–11, 1987
31. Wolstenholme AJ, Fairweather I, Prichard R, von Samson-Himmelstjerna G, Sangster NC. Drug resistance in veterinary helminths. Trends in Parasitology 20, 469–76, 2004
32. Wooster MJ, Woodgate RG, Chick BF. Reduced efficacy of ivermectin, abamectin and moxidectin against field isolates of Haemonchus contortus. Australian Veterinary Journal 79, 840–2, 2001