Moxidectin: Persistence and efficacy against drug-resistant Ostertagia circumcincta

Journal of Veterinary Pharmacology and Therapeutics

Volumn 22, Issue 1, 1999, Pages 2-5

  Sutherland, I A ^a   Leathwick, D M ^a   Brown, A E ^a  

^a AGRESEARCH GRASSLANDS   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

IVERMECTIN; MOXIDECTIN;

ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FECES ANALYSIS; NEMATODIASIS; NONHUMAN; OOCYTE; OSTERTAGIA; PRIORITY JOURNAL; SHEEP DISEASE;

ANIMALS; ANTHELMINTICS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE; FECES; IVERMECTIN; MACROLIDES; OSTERTAGIA; OSTERTAGIASIS; PARASITE EGG COUNT; SHEEP; SHEEP DISEASES;

EID: 0033030755     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.1999.00188.x     Document Type: Article

References (24)

1. Afzal, J., Stout, S.J., DaCunha, R. & Miller, P. (1994) Moxidectin: absorption, tissue distribution, excretion and biotransformation of 14C-labelled moxidectin in sheep. Journal of Agriculture and Food Chemistry, 42, 1767-1773.
2. Alvinerie, M., Sutra, J.F., Lanusse, C. & Galtier, P. (1996) Plasma profile study of moxidectin in a cow and its suckling calf. Veterinary Research, 27, 545-549.
3. Arena, J., Liu, K.K., Paress, P.S., Frazier, E.G., Cully, D.F., Mrozik, H. & Schaeffer, J. (1995) The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity. Journal of Parasitology, 81, 286-294.
4. Conder, G.A., Thompson, D.P. & Johnson, S.S. (1993) Demonstration of co-resistance of Haemonchus contortus to ivermectin and moxidectin. Veterinary Record, 132, 651-652.
5. Craig, T.M., Hatfield, T.A., Pankavich, J.A. & Wang, G.T. (1992) Efficacy of moxidectin against an ivermectin-resistant strain of Haemonchus contortus in sheep. Veterinary Parasitology, 41, 329-333.
6. Cully, D.F., Wilkinson, H., Vassilatis, D.K., Etter, A. & Arena, J.P. (1996) Molecular biology and electrophysiology of glutamate-gated chloride channels of invertebrates. Parasitology, 113, S191-S200.
7. Dobson, R.J., Le Jambre, L., Gill, J.H. & Gill, H.S. (1996) Management of anthelmintic resistance: inheritance of resistance and selection with persistent drugs. International Journal for Parasitology, 26, 993-1000.
8. Hennessy, D.R. & Prichard, R.K. (1981) The role of absorbed drugs in the efficacy of oxfendazole against gastrointestinal parasites. Veterinary Research Communications, 5, 45-49.
9. Kieran, P.J. (1994) Moxidectin against ivermectin-resistant nematodes - a global view. Australian Veterinary Journal, 71, 18-20.
10. Lanusse, C., Lifschitz, A., Virkel, G., Alvarez, L., Sanchez, S., Sutra, J.F., Galtier, P. & Alvinerie, M. (1997) Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle. Journal of Veterinary Pharmacology and Therapeutics, 20, 91-99.
11. Leathwick, D.M. (1995) A case of moxidectin failing to control ivermectin resistant Ostertagia species in goats. The Veterinary Record, 136, 443-144.
12. Martin, P.J. & Pennington, A.J. (1989) A patch clamp study of effects of dihydroavermectin on Ascaris muscle. British Journal of Pharmacology, 98, 747-756.
13. Overend, D.J., Philips, M.L., Poulton, A.L. & Foster, C.E.D. (1994) Anthelmintic resistance in Australian sheep nematode populations. Australian Veterinary Journal, 71, 117-121.
14. Pankavich, J.A., Berger, H. & Simkins, K.L. (1992) Efficacy of moxidectin, nemadectin and ivermectin against an ivermectin-resistant strain of Haemonchus contortus in sheep. Veterinary Record, 130, 241-243.
15. Rendell, D. & Callinan, L. (1996) The duration of anthelmintic effects of moxidectin and ivermectin in grazing sheep. Australian Veterinary Journal, 73, 35.
16. Sangster, N. (1996) Pharmacology of anthelmintic resistance. Parasitology, 113, S201-S216.
17. Sangster, N.C., Richard, J.M., Hennessy, D.R., Steel, J.W. & Collins, G.H. (1991) Disposition of oxfendazole in goats and efficacy compared with sheep. Research in Veterinary Science, 51, 258-263.
18. Shoop, W.L., Haines, H.W., Michael, B.F. & Eary, C.H. (1993) Mutual resistance to avermectins and milbemycins: oral activity of ivermectin and moxidectin against ivermectin-resistant and susceptible nematodes. The Veterinary Record, 133, 445-447.
19. Shoop, W.L., Mrozik, H. & Fisher, M.H. (1995) Structure and activity of avermectins and milbemycins in animal health. Veterinary Parasitology, 59, 139-156.
20. Steel, J.W. (1993) Pharmacokinetics and metabolism of avermectins in livestock. Veterinary Parasitology, 48, 45-57.
21. Sutherland, I.A., Leathwick, D.M., Brown, A.E. & Miller, C.M. (1997) Prophylactic efficacy of persistent anthelmintics against challenge with drug-resistant and susceptible Ostertagia circumcincta. Veterinary Record, 141, 120-123.
22. Tranquilli, W.J., Paul, A.J. & Todd, K.S. (1991) Assessment of toxicosis induced by high-dose administration of milbemycin oxime in collies. American Journal of Veterinary Research, 52, 1170-1172.
23. Varady, M., Praslicka, J. & Corba, J. (1995) Efficacy of moxidectin against multiple-resistant Ostertagia spp. in lambs. New Zealand Veterinary Journal, 43, 89-90.
24. Vieira, L.S., Berne, M.E., Cavalcante, A.C. & Costa, C.A. (1992) Haemonchus contortus resistance to ivermectin and netobimin in Brazilian sheep. Veterinary Parasitology, 45, 111-116.