Pharmacokintics of the Ginkgo Bfollowing intravenous administration of Ginkgo B emulsion in rats

Biological and Pharmaceutical Bulletin

Volumn 30, Issue 1, 2007, Pages 1-5

  Chen, Wei Dong ^a,b   Liang, Yan ^a   Xie, Lin ^a   Lu, Tong ^a   Liu, Xiao Dong ^a   Wang, Guang Ji ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b Hospital of the Seventeenth Metallurgical Construction Company   (China)

Author keywords

Ginkgolide B; HPLC ESI MS; Metabolism; Pharmacokinetics

Indexed keywords

DRUG METABOLITE; GINKGO BILOBA EXTRACT; GINKGOLIDE B; PLASMA PROTEIN; GINKGOLIDE; HERBACEOUS AGENT; LACTONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; COMPARTMENT MODEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DOSE COMPARISON; DRUG EXCRETION; DRUG HALF LIFE; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG TISSUE LEVEL; ELECTROSPRAY MASS SPECTROMETRY; EMULSION; EXPERIMENTAL RAT; FEMALE; GINKGO BILOBA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MULTIPLE DRUG DOSE; NONHUMAN; RAT; SINGLE DRUG DOSE; ANIMAL; BILE; BIOLOGICAL MODEL; BIOTRANSFORMATION; BLOOD; CHEMISTRY; DRUG ADMINISTRATION; FECES; HALF LIFE TIME; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; METABOLIC CLEARANCE RATE; METABOLISM; METHODOLOGY; PLANT LEAF; PROTEIN BINDING; SPRAGUE DAWLEY RAT; STATISTICAL MODEL; TISSUE DISTRIBUTION; URINE;

ANIMALS; AREA UNDER CURVE; BILE; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG ADMINISTRATION SCHEDULE; DRUGS, CHINESE HERBAL; EMULSIONS; FECES; GINKGO BILOBA; GINKGOLIDES; HALF-LIFE; HUMANS; INJECTIONS, INTRAVENOUS; LACTONES; LINEAR MODELS; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; PLANT LEAVES; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TISSUE DISTRIBUTION;

EID: 33846046086     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.30.1     Document Type: Article

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