Optimized linkage and quenching strategies for quantum dot molecular beacons

Molecular and Cellular Probes

Volumn 21, Issue 2, 2007, Pages 116-124

  Cady, Nathaniel C ^a   Strickland, Aaron D ^a   Batt, Carl A ^a  

^a Department of Obstetrics Gynecology   (United States)

Author keywords

Biosensor; Detection; DNA; Molecular beacon; Quantum dots

Indexed keywords

AMIDE; BIOTIN; COMPLEMENTARY DNA; DNA; QUANTUM DOT; STREPTAVIDIN;

ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; DNA DETERMINATION; DNA SEQUENCE; FLUORESCENCE; HYBRIDIZATION; HYDRODYNAMICS; MEASUREMENT; MOLECULAR BEACON; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SEMICONDUCTOR;

BASE SEQUENCE; DNA; FLUORESCENCE RESONANCE ENERGY TRANSFER; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDE PROBES; QUANTUM THEORY; SPECTROPHOTOMETRY;

EID: 33846033425     PISSN: 08908508     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcp.2006.09.001     Document Type: Article

References (23)

1. Hohng S., and Ha T. Single-molecule quantum-dot fluorescence resonance energy transfer. Chem Phys Chem 6 (2005) 956-960
2. Willard D.M., and Van Orden A. Quantum dots: resonant energy-transfer sensor. Nat Mater 2 (2003) 575-576
3. Han M., Gao X., Su J.Z., and Nie S. Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules. Nat Biotechnol 19 (2001) 631-635
4. Medintz I.L., Clapp A.R., Mattoussi H., Goldman E.R., Fisher B., and Mauro J.M. Self-assembled nanoscale biosensors based on quantum dot FRET donors. Nat Mater 2 (2003) 630-638
5. Medintz I.L., Uyeda H.T., Goldman E.R., and Mattoussi H. Quantum dot bioconjugates for imaging, labelling and sensing. Nat Mater 4 (2005) 435-446
6. Liu X., Farmerie W., Schuster S., and Tan W. Molecular beacons for DNA biosensors with micrometer to submicrometer dimensions. Anal Biochem 283 (2000) 56-63
7. Robelek R., Niu L., Schmid E.L., and Knoll W. Multiplexed hybridization detection of quantum dot-conjugated DNA sequences using surface plasmon enhanced fluorescence microscopy and spectrometry. Anal Chem 76 (2004) 6160-6165
8. Epstein J., Biran I., and Walt D.R. Fluorescence-based nucleic acid detection and microarrays. Anal Chim Acta 469 (2002) 3-36
9. Kim J.H., Morikis D., and Ozkan M. Adaptation of inorganic quantum dots for stable molecular beacons. Sensors Actuators B 102 (2004) 315-319
10. Tyagi S., and Kramer F.R. Molecular beacons: probes that fluoresce upon hybridization. Nat Biotechnol 14 (1996) 303-308
11. Tan L., Li Y., Drake T.J., Moroz L., Wang K., Li J., et al. Molecular beacons for bioanalytical applications. Analyst 130 (2005) 1002-1005
12. Vet J.A., and Marras S.A. Design and optimization of molecular beacon real-time polymerase chain reaction assays. Methods Mol Biol 288 (2005) 273-290
13. Tsourkas A., Behlke M.A., Rose S.D., and Bao G. Hybridization kinetics and thermodynamics of molecular beacons. Nucleic Acids Res 31 (2003) 1319-1330
14. Altschul S.F., Gish W., Miller W., Myers E.W., and Lipman D.J. Basic local alignment search tool. J Mol Biol 215 (1990) 403-410
15. Hermanson G.T. Bioconjugate techniques (1996), Academic Press, New York
16. Clapp A.R., Medintz I.L., Mauro J.M., Fisher B.R., Bawendi M.G., and Mattoussi H. Fluorescence resonance energy transfer between quantum dot donors and dye-labeled protein acceptors. J Am Chem Soc 126 (2004) 301-310
17. Du H., Strohsahl C.M., Camera J., Miller B.L., and Krauss T.D. Sensitivity and specificity of metal surface-immobilized "molecular beacon" biosensors. J Am Chem Soc 127 (2005) 7932-7940
18. Gueroui Z., and Libchaber A. Single-molecule measurements of gold-quenched quantum dots. Phys Rev Lett 93 (2004) 166108
19. Dubertret B., Calame M., and Libchaber A.J. Single-mismatch detection using gold-quenched fluorescent oligonucleotides. Nat Biotechnol 19 (2001) 365-370
20. Venkateswarlu V., and Manjunath K. Preparation, characterization and in vitro release kinetics of clozapine solid lipid nanoparticles. J Control Rel 95 (2004) 627-638
21. O'Neal D., Harrip P., Dragicevic G., Rae D., and Best J.D. A comparison of LDL size determination using gradient gel electrophoresis and light-scattering methods. J Lipid Res 39 (1998) 2086-2090
22. Pazy Y., Laitinen O.H., Ravoy B., Kulomaa M.S., Wilchek M., Bayer E.A., et al. Crystallization and preliminary X-ray analysis of W120 K mutant of streptavidin. Acta Crystallogr D Biol Crystallogr 57 (2001) 1885-1886
23. Dyadyusha L., Yin H., Jaiswal S., Brown T., Baumberg J.J., Booy F.P., et al. Quenching of CdSe quantum dot emission, a new approach for biosensing. Chem Commun (Cambridge) (2005) 3201-3203