-
1
-
-
0033619244
-
A chain initiation factor common to both modular and aromatic polyketide synthases
-
7 other authors
-
Bisang, C., Long, P. F., Cortes, J. & 7 other authors (1999). A chain initiation factor common to both modular and aromatic polyketide synthases. Nature 401, 502-505.
-
(1999)
Nature
, vol.401
, pp. 502-505
-
-
Bisang, C.1
Long, P.F.2
Cortes, J.3
-
2
-
-
0029592773
-
A new DNA sequence assembly program
-
Bonfield, J. K., Smith, K. F. & Staden, R. (1995). A new DNA sequence assembly program. Nucleic Acids Res 23, 4992-4999.
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 4992-4999
-
-
Bonfield, J.K.1
Smith, K.F.2
Staden, R.3
-
3
-
-
0042307438
-
Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases
-
Caffrey, P. (2003). Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases. Chembiochem 4, 654-657.
-
(2003)
Chembiochem
, vol.4
, pp. 654-657
-
-
Caffrey, P.1
-
4
-
-
0141706445
-
Active-site residue, domain and module swaps in modular polyketide synthases
-
7 other authors
-
Del Vecchio, F., Petkovic, H., Kendrew, S. G. & 7 other authors (2003). Active-site residue, domain and module swaps in modular polyketide synthases. J Ind Microbiol Biotechnol 30, 489-494.
-
(2003)
J Ind Microbiol Biotechnol
, vol.30
, pp. 489-494
-
-
Del Vecchio, F.1
Petkovic, H.2
Kendrew, S.G.3
-
5
-
-
33845974544
-
Rapamycin-like macrolide, and a new strain of streptomycete which produces it
-
International patent publication number WO 94/18207
-
Fehr, T., Sanglier, J.-J. & Schuler, W. (1994). Rapamycin-like macrolide, and a new strain of streptomycete which produces it. International patent publication number WO 94/18207.
-
(1994)
-
-
Fehr, T.1
Sanglier, J.-J.2
Schuler, W.3
-
6
-
-
0033034203
-
Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506
-
Gold, B. G., Densmore, V., Shou, W., Matzuk, M. M. & Gordon, H. S. (1999). Immunophilin FK506-binding protein 52 (not FK506-binding protein 12) mediates the neurotrophic action of FK506. J Pharmacol Exp Ther 289, 1202-1210.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 1202-1210
-
-
Gold, B.G.1
Densmore, V.2
Shou, W.3
Matzuk, M.M.4
Gordon, H.S.5
-
7
-
-
17744386191
-
Non-FK506-binding protein-12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration
-
Gold, B. G., Armistead, D. M. & Wang, M. S. (2005). Non-FK506-binding protein-12 neuroimmunophilin ligands increase neurite elongation and accelerate nerve regeneration. J Neurosci Res 80, 56-65.
-
(2005)
J Neurosci Res
, vol.80
, pp. 56-65
-
-
Gold, B.G.1
Armistead, D.M.2
Wang, M.S.3
-
8
-
-
0034998137
-
Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons
-
Guo, X., Dawson, V. L. & Dawson, T. M. (2001). Neuroimmunophilin ligands exert neuroregeneration and neuroprotection in midbrain dopaminergic neurons. Eur J Neurosci 13, 1683-1693.
-
(2001)
Eur J Neurosci
, vol.13
, pp. 1683-1693
-
-
Guo, X.1
Dawson, V.L.2
Dawson, T.M.3
-
9
-
-
0028947904
-
An oligonucleotide-directed dual amber method for site-directed mutagenesis
-
Hashimoto-Gotoh, T., Mizuno, T., Ogasahara, Y. & Nakagawa, M. (1995). An oligonucleotide-directed dual amber method for site-directed mutagenesis. Gene 23, 271-275.
-
(1995)
Gene
, vol.23
, pp. 271-275
-
-
Hashimoto-Gotoh, T.1
Mizuno, T.2
Ogasahara, Y.3
Nakagawa, M.4
-
10
-
-
0028841535
-
Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA: Acyl carrier protein transacylase domains in modular polyketide synthases
-
7 other authors
-
Haydock S. F., Aparicio, J. F., Molnar, I. & 7 other authors (1995). Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA: acyl carrier protein transacylase domains in modular polyketide synthases. FEBS Lett 374, 246-248.
-
(1995)
FEBS Lett
, vol.374
, pp. 246-248
-
-
Haydock, S.F.1
Aparicio, J.F.2
Molnar, I.3
-
11
-
-
4544282309
-
The putative elaiophylin biosynthetic gene cluster in Streptomyces sp. DSM4137 is adjacent to genes encoding adenosylcobalamin-dependent methylmalonyl CoA mutase and to genes for synthesis of cobalamin
-
Haydock, S. F., Mironenko, T., Ghoorahoo, H. I. & Leadlay, P. F. (2004). The putative elaiophylin biosynthetic gene cluster in Streptomyces sp. DSM4137 is adjacent to genes encoding adenosylcobalamin-dependent methylmalonyl CoA mutase and to genes for synthesis of cobalamin. J Biotechnol 113, 55-68.
-
(2004)
J Biotechnol
, vol.113
, pp. 55-68
-
-
Haydock, S.F.1
Mironenko, T.2
Ghoorahoo, H.I.3
Leadlay, P.F.4
-
12
-
-
33745949592
-
Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748
-
He, M., Halti, B., Summers, M., Feng, X. & Hucul, J. (2006). Isolation and characterization of meridamycin biosynthetic gene cluster from Streptomyces sp. NRRL 30748. Gene 377, 109-118.
-
(2006)
Gene
, vol.377
, pp. 109-118
-
-
He, M.1
Halti, B.2
Summers, M.3
Feng, X.4
Hucul, J.5
-
13
-
-
0003869903
-
-
Norwich: John Innes Foundation
-
Kieser, T., Bibb, M. J., Buttner, M. J., Chater, K. F. & Hopwood, D. A. (2000). Practical Streptomyces Genetics. Norwich: John Innes Foundation.
-
(2000)
Practical Streptomyces Genetics
-
-
Kieser, T.1
Bibb, M.J.2
Buttner, M.J.3
Chater, K.F.4
Hopwood, D.A.5
-
14
-
-
0033514424
-
Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units
-
Lau, J., Fu, H., Cane, D. E. & Khosia, C. (1999). Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units. Biochemistry 38, 1643-1651.
-
(1999)
Biochemistry
, vol.38
, pp. 1643-1651
-
-
Lau, J.1
Fu, H.2
Cane, D.E.3
Khosia, C.4
-
15
-
-
20444463024
-
Promoting repair in multiple sclerosis: Problems and prospects
-
Lubetski, C., Williams, A. & Stankoff, B. (2005). Promoting repair in multiple sclerosis: problems and prospects. Curr Opin Neurol 18, 237-244.
-
(2005)
Curr Opin Neurol
, vol.18
, pp. 237-244
-
-
Lubetski, C.1
Williams, A.2
Stankoff, B.3
-
16
-
-
0026575735
-
Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector
-
MacNeil, D. J., Gewain, K. M., Ruby, C. L., Dezeny, G., Gibbons, P. H. & MacNeil, T. (1992). Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector. Gene 111, 61-68.
-
(1992)
Gene
, vol.111
, pp. 61-68
-
-
MacNeil, D.J.1
Gewain, K.M.2
Ruby, C.L.3
Dezeny, G.4
Gibbons, P.H.5
MacNeil, T.6
-
17
-
-
0032530781
-
The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506
-
Motamedi, H. & Shafiee, A. (1998). The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. Eur J Biochem 256, 528-534.
-
(1998)
Eur J Biochem
, vol.256
, pp. 528-534
-
-
Motamedi, H.1
Shafiee, A.2
-
19
-
-
0037088657
-
A new substrate specificity for acyl transferase domains of the ascomycin polyketide synthase in S. hygroscopicus
-
Reeves, C. D., Chung, L. M., Liu, Y., Xue, Q., Carney, J. R., Revill, W. P. & Katz, L. (2002). A new substrate specificity for acyl transferase domains of the ascomycin polyketide synthase in S. hygroscopicus. J Biol Chem 277, 9155-9160.
-
(2002)
J Biol Chem
, vol.277
, pp. 9155-9160
-
-
Reeves, C.D.1
Chung, L.M.2
Liu, Y.3
Xue, Q.4
Carney, J.R.5
Revill, W.P.6
Katz, L.7
-
20
-
-
0028869649
-
Meridamycin: A novel nonimmunosuppressive FKB12 ligand from Streptomyces hygroscopicus
-
Salituro, G. M., Zink D. L., Dahl, A., Nielson, J., Wu, E., Huang, L., Kastner, C. & Dumont, F. J. (1995). Meridamycin: a novel nonimmunosuppressive FKB12 ligand from Streptomyces hygroscopicus. Tetrahedron Lett 36, 997-1000.
-
(1995)
Tetrahedron Lett
, vol.36
, pp. 997-1000
-
-
Salituro, G.M.1
Zink, D.L.2
Dahl, A.3
Nielson, J.4
Wu, E.5
Huang, L.6
Kastner, C.7
Dumont, F.J.8
-
21
-
-
0004136246
-
-
2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory
-
Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989). Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
-
(1989)
Molecular Cloning: A Laboratory Manual
-
-
Sambrook, J.1
Fritsch, E.F.2
Maniatis, T.3
-
22
-
-
0029098323
-
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin
-
10 other authors
-
Schwecke, T., Aparicio, J. F., Molnar, I. & 10 other authors (1995). The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin. Proc Natl Acad Sci U S A 92, 7839-7843.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 7839-7843
-
-
Schwecke, T.1
Aparicio, J.F.2
Molnar, I.3
-
23
-
-
23644461186
-
Immunosuppressants: Neuroprotection and promoting neurological recovery following peripheral nerve and spinal cord lesions
-
Sosa, I., Reyes, O. & Kuffler, D. P. (2005). Immunosuppressants: neuroprotection and promoting neurological recovery following peripheral nerve and spinal cord lesions. Exp Neurol 195, 7-15.
-
(2005)
Exp Neurol
, vol.195
, pp. 7-15
-
-
Sosa, I.1
Reyes, O.2
Kuffler, D.P.3
-
24
-
-
0034887171
-
Polyketide synthases: A millennium review
-
Staunton, J. & Weissman, K. J. (2001). Polyketide synthases: a millennium review. Nat Prod Rep 18, 380-416.
-
(2001)
Nat Prod Rep
, vol.18
, pp. 380-416
-
-
Staunton, J.1
Weissman, K.J.2
-
25
-
-
0030975605
-
Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A
-
Steiner, J. P., Connolly, M. A., Valentine, H. L., Hamilton, G. S., Dawson, T. M., Hester, L. & Snyder, L. (1997). Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. Nat Med 3, 421-428.
-
(1997)
Nat Med
, vol.3
, pp. 421-428
-
-
Steiner, J.P.1
Connolly, M.A.2
Valentine, H.L.3
Hamilton, G.S.4
Dawson, T.M.5
Hester, L.6
Snyder, L.7
-
26
-
-
0036175076
-
'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters
-
Sun, Y., Zhou, X., Liu, J., Bao, K., Zhang, G., Tu, G., Kieser, T. & Deng, Z. (2002). 'Streptomyces nanchangensis', a producer of the insecticidal polyether antibiotic nanchangmycin and the antiparasitic macrolide meilingmycin, contains multiple polyketide gene clusters. Microbiology 148, 361-371.
-
(2002)
Microbiology
, vol.148
, pp. 361-371
-
-
Sun, Y.1
Zhou, X.2
Liu, J.3
Bao, K.4
Zhang, G.5
Tu, G.6
Kieser, T.7
Deng, Z.8
-
27
-
-
1442350420
-
Possibility of non-immunosuppressive immunophilin ligands as potential therapeutic agents for Parkinson's disease
-
Tanaka, K. & Ogawa, N. (2004). Possibility of non-immunosuppressive immunophilin ligands as potential therapeutic agents for Parkinson's disease. Curr Pharm Des 10, 669-677.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 669-677
-
-
Tanaka, K.1
Ogawa, N.2
-
28
-
-
0025826967
-
Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex
-
Van Duyne, G. D., Standaert, R. F., Karplus, P. A., Schreiber, S. L. & Clardy, J. (1991). Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex. Science 252, 839-842.
-
(1991)
Science
, vol.252
, pp. 839-842
-
-
Van Duyne, G.D.1
Standaert, R.F.2
Karplus, P.A.3
Schreiber, S.L.4
Clardy, J.5
-
29
-
-
0027439390
-
Atomic structures of the human immunophilin FKB-12 complexes with FK506 and rapamycin
-
Van Duyne, G. D., Standaert, R. F., Karplus, P. A., Schreiber, S. L. & Clardy, J. (1993). Atomic structures of the human immunophilin FKB-12 complexes with FK506 and rapamycin. J Mol Biol 229, 105-124.
-
(1993)
J Mol Biol
, vol.229
, pp. 105-124
-
-
Van Duyne, G.D.1
Standaert, R.F.2
Karplus, P.A.3
Schreiber, S.L.4
Clardy, J.5
-
30
-
-
0034643859
-
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units
-
Wu, K., Chung, L., Revill, W. P., Katz, L. & Reeves, C. D. (2000). The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units. Gene 251, 81-90.
-
(2000)
Gene
, vol.251
, pp. 81-90
-
-
Wu, K.1
Chung, L.2
Revill, W.P.3
Katz, L.4
Reeves, C.D.5
|