Susceptibility of aging human bone to mixed-mode fracture increases bone fragility

Bone

Volumn 38, Issue 1, 2006, Pages 105-111

  George, W T ^a   Vashishth, D ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Aging; Bone quality; Damage; Fatigue; Multiaxial; Torsion

Indexed keywords

ADULT; AGED; AGING; BONE; BONE FRAGILITY; CONFERENCE PAPER; CONTROLLED STUDY; CORTICAL BONE; DISEASE PREDISPOSITION; FATIGUE; FRAGILITY FRACTURE; HUMAN; HUMAN TISSUE; INCIDENCE; LOADING TEST; MALE; PHYSIOLOGY; QUALITY CONTROL; SCREENING TEST; SHEAR STRESS; STATISTICAL SIGNIFICANCE;

ADULT; AGED; AGED, 80 AND OVER; AGING; DISEASE SUSCEPTIBILITY; FRACTURES, STRESS; HUMANS; MALE; MICROSCOPY, ELECTRON, SCANNING; MIDDLE AGED; STRESS, MECHANICAL; TENSILE STRENGTH; TIBIA; TIBIAL FRACTURES; TORSION; WEIGHT-BEARING;

EID: 29344456121     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2005.08.002     Document Type: Conference Paper

References (48)

1. P. Augat, H. Iida, Y. Jiang, E. Diao, and H.K. Genant Distal radius fractures: mechanics of injury and strength prediction by bone mineral assessment J. Orthop. Res. 16 5 1998 629 635
2. A.J. Bailey, T.J. Sims, E.N. Ebbesen, J.P. Mansell, J.S. Thomsen, and L. Mosekilde Age-related changes in the biochemical properties of human cancellous bone collagen: relationship to bone strength Calcif. Tissue Int. 65 1999 203 210
3. T.M. Boyce, and R.D. Bloebaum Cortical aging differences and fracture implications for the human femoral neck Bone 14 5 1993 769 778
4. D.B. Burr, M.R. Forwood, D.P. Fyhrie, R.B. Martin, M.B. Schaffler, and C.H. Turner Bone microdamage and skeletal fragility in osteoporosis and stress fracture J. Bone Miner. Res. 12 1997 6 15
5. D.B. Burr, and M. Hooser Alterations to the en bloc basic fuchsin staining protocol for the demonstration of microdamage produced in-vivo Bone 17 1995 431 433
6. D.B. Burr, C. Milgrom, D.P. Fyhrie, M. Forwood, M. Nyska, and A. Finestone In vivo measurement of human tibial strains during vigorous activity Bone 18 1996 405 410
7. K.D. Cao, M.J. Grimm, and K.H. Yang Load sharing within a human lumbar vertebral body using the finite element method Spine 26 12 2001 E253 E260
8. D.R. Carter Anisotropic analysis of strain rosette information from cortical bone J. Biomech. 11 1978 199 202
9. J. Catanese, R.A. Bank, J.M. Tekoppele, and T.M. Keaveny Increased cross-linking by non-enzymatic glycation reduces the ductility of bone and bone collagen Proceedings of the ASME 1999 Bioengineering Conference BED-vol. 42 1999 267 268
10. S. Chatterji, J.C. Wall, and J.W. Jeffery Age-related changes in the orientation and particle size of the mineral phase in human femoral cortical bone Calcif. Tissue Int. 33 1981 567 574
11. A.M. Courtney, W.C. Hayes, and L.J. Gibson Age-related differences in post-yield damage in human cortical bone. Experiment and model J. Biomech. 29 1996 1463 1471
12. J.D. Currey Some effects of ageing in human Haversian systems J. Antat. 98 1964 69 75
13. J. Devlukia, and J. Davies Fatigue analysis of a vehicle structural component under biaxial loading Biaxial Fatigue Conference 1985 Sheffield University Press
14. F.G. Evans Mechanical properties and histology of cortical bone from younger and older men Anat. Rec. 185 1975 1 11
15. D.P. Fyhrie, C. Milgrom, S.J. Hoshaw, S. Dar, D. Drumb, and D.B. Burr Effect of fatiguing exercise on longitudinal bone strain as related to stress fracture in humans Ann. Biomed. Eng. 26 1998 660 665
16. W.T. George, and D. Vashishth Damage mechanisms and failure modes of cortical bone under components of physiological loading J. Orthop. Res. 23 2005 1047 1053
17. R.P. Heaney Is there a role for bone quality in fragility fractures? Calcif Tissue Int. 53 1993 S3 S6 [Suppl.]
18. A. Hoiseth, A. Alho, and T. Husby Femoral cortical/cancellous bone related to age Acta Radiol. 31 6 1990 626 627
19. B.H. Jones, J.M. Harris, T.N. Vinh, and C. Rubin Exercise-induced stress fractures and stress reactions of bone: epidemiology, etiology, and classification Exerc. Sport Sci. Rev. 17 1989 379 422
20. G.R. Jordan, N. Loveridge, K.L. Bell, J. Power, N. Rushton, and J. Reeve Spatial clustering of remodeling osteons in the femoral neck cortex: a cause of weakness in hip fracture? Bone 26 3 2000 305 313
21. K. Kendall Control of crack interface in composites Proc. R. Soc. London 341 1975 409 428
22. E.R. Kerley The microscopic determination of age in human bone Am. J. Phys. Anthropol. 23 1965 149 164
23. D.F. Knott, K.J. Jepsen, and D.T. Davy Age-related changes in tensile damage accumulation behavior of human cortical bone Trans. Orthop. Res. Soc. 46th Annual Meeting 2000 Orthopedic Research Society 10
24. R. Lakes, and S. Saha Cement line motion in bone Science 204 4392 1979 (May 4) 501 503
25. K.B. Lease, R.I. Stephens, Y.Y. Jiang, and P. Kurath Fatigue of particulate reinforced aluminum metal matrix composite subjected to axial, torsional and combined axial/torsional loading conditions Fatigue Fract. Eng. Mater. Struct. 19 1996 1031 1043
26. K. Liao, E.R. George, and K.L. Reifsnider Characterization of ceramic matrix composite tubes under uniaxial/biaxial monotonic and cyclic loading. Multiaxial fatigue and deformation testing techniques ASTM STP 1280 1997 224 240
27. J.C. Lotz, E.J. Cheal, and W.C. Hayes Fracture prediction for the proximal femur using finite element models: part II-nonlinear analysis J. Biomech. 113 4 1991 361 365
28. R.B. Martin, D.B. Burr, and N.A. Sharkey Skeletal Tissue Mechanics 1998 Springer New York
29. J.L. Melton Epidemiology of fractures B. Lawernce Riggs L. Joseph Melton Osteoporosis: Etiology, Diagnosis and Management 1988 Raven Press New York 133 154
30. J. Muller, D. Vashishth, and C.M. Milgrom Anisotropic analysis of in-vivo strain gauge date yields clues about fatigue fracture Translations of the 50th Annual Meeting of the Orthopaedic Research Society 2004
31. C. Milgrom, A. Finestone, A. Simkin, I. Ekenman, S. Mendelson, and M. Millgram In vivo strain measurements to evaluate the strengthening potential of exercises on the tibial bone J. Bone Joint Surg. 82-B4 2000 591 594
32. T.L. Norman, Y.N. Yeni, C.U. Brown, and Z. Wang Influence of microdamage on fracture toughness of human femur and tibia Bone 23 1998 303 306
33. C. Nyssen-Behets, P.Y. Duchesne, and A. Dhem Structural changes with aging in cortical bone of the human tibia Gerontology 43 6 1997 316 325
34. D.J. Ortner Aging effects on osteon remodeling Calcif. Tissue Res. 18 1975 27 36
35. S.M. Ott When bone mass fails to predict bone failure Calcif Tissue Int. 53 1993 S7 S13 [Suppl.]
36. D.L. Peterson, J.S. Skraba, J.M. Moran, and A.S. Greenwald Fracture of long bones: rate effects under singular and combined loading states J. Orthop. Res. 1 1984 244 250
37. N.F. Ray, J.K. Chan, M. Thamer, and L.J. Melton Medical expenditures for the treatment of osteoporotic fractures in the United States in 1995: report from the National Osteoporosis Foundation J. Bone Miner. Res. 12 1997 24 35
38. M.B. Schaffler, E.L. Radin, and D.B. Burr Long-term fatigue behavior of compact bone at low strain magnitude and rate Bone 11 1990 321 326
39. M.B. Schaffler, K. Choi, and C. Milgrom Aging and matrix microdamage accumulation in human compact bone Bone 17 1995 521 525
40. B.R. Singer, G.J. McLauchlan, C.M. Robinson, and J. Christe Epidemiology of fractures in 15000 adults: the influence of age and gender J. Bone Joint. Surg. 80-B 1998 243 248
41. D.F. Socie Critical plane approaches for multiaxial damage assessment D.L. McDowell R. Ellis Advances in Multiaxial Fatigue ASTM STP vol. 1191 1993 7 36
42. D.F. Socie, and G.B. Marquis Multiaxial Fatigue 2000 Publisher: Society of Automotive Engineers, Inc. Warrendale, PA
43. D. Vashishth, T.L. Norman, S. Nivargikar, J.C. Behiri, and W. Bonfield Microstructural response of cortical bone subjected to tensile and shear loads The Proceedings of the Second World Congress of Biomechanics vol. II, 237b 1994 Stitching World Biomechanics Nijmegen
44. D. Vashishth, J.C. Behiri, and W. Bonfield Crack growth resistance in cortical bone: concept of microcrack toughening J. Biomech. 30 1997 763 769
45. D. Vashishth, K.E. Tanner, and W. Bonfield Contribution, development and morphology of microcracking in cortical bone during crack propagation J. Biomech. 33 2000 1168 1174
46. D. Vashishth, K.E. Tanner, and W. Bonfield Fatigue of cortical bone under combined axial-torsional loading J. Orthop. Res. 19 2001 414 420
47. X. Wang, X. Shen, X. Li, and C.M. Agrawal Age-related changes in the collagen network and toughness of bone Bone 31 1 2002 1 7
48. P. Zioupos, and J.D. Currey Changes in stiffness, strength, and toughness of human cortical bone with age Bone 22 1998 57 66